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Topic:Warmblood Horses

Warmblood horses are a group of middle-weight horse breeds known for their versatility and performance in equestrian sports such as dressage, show jumping, and eventing. They are characterized by a combination of athleticism, temperament, and conformation, which make them suitable for competitive disciplines. Breeds within this group include the Hanoverian, Dutch Warmblood, and Holsteiner, among others. The breeding and selection processes for Warmbloods focus on traits such as movement, trainability, and soundness. This page compiles peer-reviewed research studies and scholarly articles that investigate the genetics, breeding practices, performance traits, and health considerations specific to Warmblood horses.
Performance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects.
Genetics, selection, evolution : GSE    January 21, 2022   Volume 54, Issue 1 4 doi: 10.1186/s12711-021-00693-4
Ablondi M, Johnsson M, Eriksson S, Sabbioni A, Viklund ÅG, Mikko S.Warmblood fragile foal syndrome (WFFS) is a monogenetic defect caused by a recessive lethal missense point mutation in the procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 gene (PLOD1, c.2032G>A). The majority of homozygous WFFS horses are aborted during gestation. Clinical signs of affected horses include fragile skin, skin and mucosa lacerations, hyperextension of the articulations, and hematomas. In spite of its harmful effect, a relatively high frequency of WFFS carriers has been found in Warmblood horses, suggesting a heterozygote advantage. Thus, in this study our aims were to: (1) est...
Equine Proliferative Enteropathy in Weanling Foals on A German Breeding Farm: Clinical Course, Treatment and Long-Term Outcome.
Journal of equine veterinary science    January 21, 2022   Volume 111 103873 doi: 10.1016/j.jevs.2022.103873
Dohrmann J, Hildebrand F, Straub J, Wadephul R, Pusterla N, Freise F, Venner M.The goal of the current report was to describe the clinical signs, therapy and outcome of foals with suspected equine proliferative enteropathy (EPE) due to an infection with Lawsonia intracellularis. Forty foals, born on the same breeding farm, were diagnosed with suspected clinical EPE between September 2019 and January 2020. Data of these cases were analyzed retrospectively regarding the course of the disease, treatment, outcome and long-term prognosis. All horses, including randomly selected control horses, were reassessed about nine months after the suspicion of EPE. The horses affected w...
Dynamic three-dimensional computed tomographic imaging facilitates evaluation of the equine cervical articular process joint in motion.
Equine veterinary journal    January 21, 2022   Volume 55, Issue 1 83-91 doi: 10.1111/evj.13560
Schulze N, Werpy N, Gernhardt J, Fritsch G, Hildebrandt T, Vanderperren K, Klopfleisch R, Ben Romdhane R, Lischer C, Ehrle A.Dynamic computed tomography (CT) imaging has been introduced in human orthopaedics and is continuing to gain popularity. With dynamic CT, video sequences of anatomical structures can be evaluated in motion. Objective: To investigate the feasibility of dynamic CT for diagnostic imaging of the equine cervical articular process joints (APJs) and to give a detailed description of the APJ movement pattern. Methods: Descriptive cadaver imaging. Methods: Cervical specimens of twelve Warmblood horses were included. A custom-made motorised testing device was used to position and manipulate the neck spe...
Genome-Wide Association Analyses of Osteochondrosis in Belgian Warmbloods Reveal Candidate Genes Associated With Chondrocyte Development.
Journal of equine veterinary science    January 21, 2022   Volume 111 103870 doi: 10.1016/j.jevs.2022.103870
Drabbe A, Janssens S, Blott S, Ducro BJ, Fontanel M, Francois L, Schurink A, Stinckens A, Lindgren G, Van Mol B, Pille F, Buys N, Velie BD.Osteochondrosis (OC) is an important skeletal disease causing profound welfare concerns in horses. Although numerous studies have explored the genetics underlying OC in various breeds, the Belgian Warmblood (BW) remains unstudied despite having a concerning prevalence of 32.0%. As a result, this study aimed to conduct genome-wide association (GWA) analyses to identify candidate variants associated with OC in BWs. To achieve this, blood samples and radiographs were collected from 407 Belgian Warmbloods registered to one of two BW studbooks (Belgisch Warmbloedpaard and Zangersheide), and genotyp...
Histological tissue healing following high-power laser treatment in a model of suspensory ligament branch injury.
Equine veterinary journal    January 20, 2022   Volume 54, Issue 6 1114-1122 doi: 10.1111/evj.13556
Pluim M, Heier A, Plomp S, Boshuizen B, Gröne A, van Weeren R, Vanderperren K, Martens A, Dewulf J, Chantziaras I, Koene M, Luciani A, Oosterlinck M....High-power laser therapy gained popularity recently as a regenerative treatment for tendinitis and desmitis in the horse. However, studies evaluating the effects of laser therapy on tissue repair at the histological level in large mammals are lacking. Objective: To evaluate the effects of high-power laser therapy on suspensory desmitis healing, using a model of suspensory ligament branch injury. Methods: In vivo experiments. Methods: Standardised lesions were surgically induced in all four lateral suspensory branches of 12 healthy Warmblood horses. Laser therapy (class 4, 15W) was applied dail...
Genetic and genomic characterization followed by single-step genomic evaluation of withers height in German Warmblood horses.
Journal of applied genetics    January 14, 2022   Volume 63, Issue 2 369-378 doi: 10.1007/s13353-021-00681-w
Vosgerau S, Krattenmacher N, Falker-Gieske C, Seidel A, Tetens J, Stock KF, Nolte W, Wobbe M, Blaj I, Reents R, Kühn C, von Depka Prondzinski M....Reliability of genomic predictions is influenced by the size and genetic composition of the reference population. For German Warmblood horses, compilation of a reference population has been enabled through the cooperation of five German breeding associations. In this study, preliminary data from this joint reference population were used to genetically and genomically characterize withers height and to apply single-step methodology for estimating genomic breeding values for withers height. Using data on 2113 mares and their genomic information considering about 62,000 single nucleotide polymorp...
CT is a feasible imaging technique for detecting lesions in horses with elbow lameness: A study of 139 elbows in 99 horses. Zimmerman M, Schramme M, Barthélemy A, Mariën T, Thomas-Cancian A, Ségard-Weisse E.Computed tomography (CT)is increasingly available in veterinary referral practices; however, published studies describing CT lesions of the equine elbow are currently lacking. In this single-center, retrospective, observational study, horses undergoing elbow CT at Equitom between July 2015 and October 2018 were reviewed. Subchondral bone sclerosis; resorption of the radius, ulna, and humerus; osteophyte; and enthesophyte lesions were graded. One hundred thirty-nine elbows of 99 horses (16 with elbow pain and 123 control elbows) were included (median age, 9 years). Osseous cyst-like lesions (n...
Intervertebral disc degeneration in warmblood horses: Histological and biochemical characterization.
Veterinary pathology    January 4, 2022   Volume 59, Issue 2 284-298 doi: 10.1177/03009858211067463
Bergmann W, de Lest CV, Plomp S, Vernooij JCM, Wijnberg ID, Back W, Gröne A, Delany MW, Caliskan N, Tryfonidou MA, Grinwis GCM.Gross morphology of healthy and degenerated intervertebral discs (IVDs) is largely similar in horses as in dogs and humans. For further comparison, the biochemical composition and the histological and biochemical changes with age and degeneration were analyzed in 41 warmblood horses. From 33 horses, 139 discs and 2 fetal vertebral columns were evaluated and scored histologically. From 13 horses, 73 IVDs were assessed for hydration, DNA, glycosaminoglycans, total collagen, hydroxyl-lysyl-pyridinoline, hydroxylysine, and advanced glycation end-product (AGE) content. From 7 horses, 20 discs were ...
Association between Cardiac Auscultation and Echocardiographic Findings in Warmblood Horses.
Animals : an open access journal from MDPI    December 5, 2021   Volume 11, Issue 12 doi: 10.3390/ani11123463
Hövener J, Pokar J, Merle R, Gehlen H.Heart murmurs are detected frequently when auscultating horses and certain murmurs can usually be linked to specific valvular regurgitations. Limited information exists about the accuracy of these broad rules in warmblood horses and the influence of grade of the regurgitation and dimensional changes on murmur intensity. This study aims to clarify the accuracy of cardiac auscultation in warmblood horses and the influence of the grade of regurgitation and dimensional changes on the loudness of the murmur. In this retrospective study, 822 warmblood horses presented for cardiac examination in a la...
Prevalences of lumbosacral articulation anatomic variants identified on nuclear scintigraphy and transrectal ultrasonography of Selle Français Warmbloods, French Standardbred Trotters, and Thoroughbreds and agreement between results from the imaging modalities.
Journal of the American Veterinary Medical Association    November 26, 2021   Volume 260, Issue 1 115-123 doi: 10.2460/javma.20.08.0428
Vautravers G, Audigié F, Denoix JM.To describe scintigraphic and transrectal ultrasonographic anatomic variants of the lumbosacral (LS) articulation in horses and to determine the agreement between results obtained with each imaging modality. 243 horses (81 Selle Français Warmbloods, 81 French Standardbred Trotters, and 81 Thoroughbreds). A retrospective search of clinical records was conducted to identify horses that had undergone nuclear scintigraphy and transrectal ultrasonography of the LS region of the vertebral column between January 2016 and December 2019. Scintigraphic images were evaluated by 2 observers blinded to th...
Retinal detachment secondary to vitreoretinopathy in two closely related warmblood horses.
Open veterinary journal    November 19, 2021   Volume 11, Issue 4 672-679 doi: 10.5455/OVJ.2021.v11.i4.18
Vercruysse E, Naranjo C, Sauvage A, Vandersmissen M, Grauwels M, Monclin S.To describe the clinical, diagnostic imaging, and histopathological findings of two visually impaired closely related horses and to identify a possible cause. Methods: Two warmblood horses, with a common dam and sire, were presented to the ophthalmology department of Liège for investigation of impaired vision. Information collected included physical and ophthalmic examination findings, results of ocular ultrasound, electroretinogram, magnetic resonance imaging (MRI), and histopathology. Ophthalmic examination, ocular ultrasound and MRI revealed a complete retinal detachment (RD) in the left e...
Computed tomographic myelography for assessment of the cervical spinal cord in ataxic warmblood horses: 26 cases (2015-2017).
Journal of the American Veterinary Medical Association    November 3, 2021   Volume 259, Issue 10 1188-1195 doi: 10.2460/javma.20.11.0614
Rovel T, Zimmerman M, Duchateau L, Adriaensen E, Mariën T, Saunders JH, Vanderperren K.To quantify the degree of dural compression and assess the association between site and direction of compression and articular process (AP) size and degree of dural compression with CT myelography. 26 client-oriented horses with ataxia. Spinal cord-to-dura and AP-to-cross-sectional area of the C6 body ratios (APBRs) were calculated for each noncompressive site and site that had > 50% compression of the subarachnoid space. Site of maximum compression had the largest spinal cord-to-dura ratio. Fisher exact test and linear regression analyses were used to assess the association between site an...
Computed tomographic examination of the articular process joints of the cervical spine in warmblood horses: 86 cases (2015-2017).
Journal of the American Veterinary Medical Association    November 3, 2021   Volume 259, Issue 10 1178-1187 doi: 10.2460/javma.20.03.0105
Rovel T, Zimmerman M, Duchateau L, Delesalle C, Adriaensen E, Mariën T, Saunders JH, Vanderperren K.To describe articular process joints (APJs) of the cervical spine in horses on the basis of CT and to determine whether abnormalities were associated with clinical signs. 86 client-owned warmblood horses. Horses that underwent CT of the cervical spine between January 2015 and January 2017 were eligible for study inclusion. Medical records were reviewed for age, body weight, breed, sex, history, clinical signs, and CT findings. Horses were divided into 3 case groups and 1 control group on the basis of clinical signs. 70 warmblood horses were cases, and 16 were controls. Abnormalities were more ...
Warmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland.
Irish veterinary journal    October 18, 2021   Volume 74, Issue 1 27 doi: 10.1186/s13620-021-00206-1
Rowe Á, Flanagan S, Barry G, Katz LM, Lane EA, Duggan V.Warmblood Fragile Foal Syndrome (WFFS) is an autosomal recessive disorder caused by a mutation in the procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1) gene. Homozygosity for the mutation results in defective collagen synthesis which clinically manifests as the birth of non viable or still born foals with abnormally fragile skin. While the mutation has been identified in non Warmblood breeds including the Thoroughbred, to date all homozygous clinically affected cases reported in the scientific literature are Warmblood foals. The objective of this study was to investigate the carrier f...
[Manganese concentrations in whole blood, plasma and serum of adult warmblood horses from 3 locations in Germany].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    August 23, 2021   Volume 49, Issue 4 234-246 doi: 10.1055/a-1525-0868
Theiner E, Weber C, Müller E, Venner M, Vervuert I.This study aimed to establish reference intervals for Mn in whole blood, plasma and serum of healthy, adult warmblood horses with known dietary Mn intake and to compare 2 methods of analysis. Methods: Between May 2018 and November 2019 a single blood sample was taken from a total of 270 clinically healthy horses (age: 3-25 years) in 3 stud farms. In lithium-heparin (LH) whole blood, LH plasma and serum Mn concentrations were analyzed by means of atomic absorption spectrometry (AAS) and inductively coupled plasma mass spectrometry (ICP-MS). The reference intervals were calculated according to t...
Investigations on the Effects of Different Calcium Supply Exceeding the Requirements on Mineral Serum Concentrations and Bone Metabolism in Young Warmblood Stallions.
Animals : an open access journal from MDPI    August 19, 2021   Volume 11, Issue 8 2439 doi: 10.3390/ani11082439
Schubert DC, Neustädter LT, Coenen M, Visscher C, Kamphues J.Since mineral supplements for horses commonly contain macro minerals, although the requirement for such is usually covered by roughage-based diets, the aim of this study was to investigate the effects of different dietary calcium levels on mineral serum concentrations and bone metabolism. The trial was conducted in 30 young warmblood stallions (2-3 years) that were divided into two groups for a five-month feeding trial. The groups were fed a hay- and oat-based diet and were either supplied with high (Ca-High) or moderate (Ca-Moderate) calcium excess. While in Ca-High calcium supply was about 2...
Magnetic Resonance Imaging Findings of the Proximal Metacarpal Region in Warmblood Horses: 36 Lame and 26 Control Limbs (2015-2021).
Frontiers in veterinary science    August 12, 2021   Volume 8 714423 doi: 10.3389/fvets.2021.714423
van Veggel E, Selberg K, van der Velde-Hoogelander B, Bolas N, Vanderperren K, Bergman HJ. This study aims to evaluate the distribution and severity of bone and soft tissue lesions in the proximal metacarpal region of warmblood horses in lame and control groups. Correlation between lesions and ability to return to work was evaluated in the lame group. This restrospective analysis evaluated 62 horses with MRI examination of the proximal metacarpal region between Sept 2015 and Feb 2021. There were 36 lame limbs and 26 control limbs. The control group included seven contralateral limbs. Proximal suspensory ligament (PSL) size was not different between the lame and control groups. Hy...
Arthroscopic removal of osteochondral fragments of the cervical articular process joints in three horses.
Veterinary surgery : VS    July 20, 2021   Volume 52, Issue 6 801-809 doi: 10.1111/vsu.13681
Schulze N, Ehrle A, Beckmann I, Lischer C.To report arthroscopic osteochondral fragment removal from the equine cervical spine articular process joints (APJs) including long-term follow-up. Methods: Case series. Methods: Three Warmblood horses with forelimb lameness and/or reduced range of motion of the cervical spine with osteochondral fragments between the cervical vertebrae C5 /C6 or C6 /C7 . Methods: Arthroscopy of the APJs of C5 /C6 and C6 /C7 was performed under general anesthesia. Following endoscopic evaluation of the joints, osteochondral fragments were removed using a rongeur. Results: All horses recovered from anesthesia wi...
Influence of Stretching Exercises, Warm-Up, or Cool-Down on the Physical Performance of Mangalarga Marchador Horses.
Journal of equine veterinary science    July 16, 2021   Volume 106 103714 doi: 10.1016/j.jevs.2021.103714
Farinelli F, de Rezende ASC, Fonseca MG, Lana ÂMQ, Leme FOP, Klein BON, Silva RHP, de Abreu AP, Damazio MJ, Melo MM.The Horse Agribusiness Complex is an important activity in the Brazilian agricultural sector. Mangalarga Marchador (MM) is the most numerous breed of horses in Brazil and its temperament and gait characteristics (4-beat stepping gait) allow for the constant growth of the breed and the performance of vs. equestrian activities. The training management currently adopted with MM horses is based on empiricism, and scientific support is necessary to improve the well-being of horses in competitions and maintain the physical integrity of these athletes. Therefore, this study aimed to verify the effect...
Corrigendum: Standing MRI lesions of the distal interphalangeal joint and podotrochlear apparatus occurs with a high frequency in Warmblood horses. The research paper involves a study targeting lesions in the foot joints of Warmblood horses, which was found to be common. However, the authors acknowledge that the initial paper contained […]
Histological and biomechanical properties of systemic arteries in young and old Warmblood horses.
PloS one    July 12, 2021   Volume 16, Issue 7 e0253730 doi: 10.1371/journal.pone.0253730
Vera L, Muylle S, Van Steenkiste G, Segers P, Decloedt A, Chiers K, van Loon G.Arterial rupture is a well-recognized cause of sudden death in horses, which mainly affects older horses. The arterial wall is known to stiffen with age, although the underlying age-related histological and biomechanical changes remain unclear. The purpose of this study was to investigate the effect of aging by histological analysis of the arterial wall and examination of the arterial wall biomechanical properties using an inflation-extension test. Entire circular samples of the proximal and distal aorta, cranial and caudal common carotid, external iliac, femoral and median artery were collect...
Sabulous cystitis in the horse: 13 cases (2013-2020).
The Canadian veterinary journal = La revue veterinaire canadienne    July 6, 2021   Volume 62, Issue 7 743-750 
Zakia LS, Gomez DE, Kenney DG, Arroyo LG.The objective of this study was to describe the clinical findings, medical management, and outcomes of horses with sabulous cystitis, and to describe a high flow bladder lavage procedure in horses that are standing or under general anesthesia. The medical records of 13 horses diagnosed with sabulous cystitis via cystoscopy between 2013 and 2020 were reviewed. Geldings (92%) and Warmbloods (46%) were overrepresented. The most common presenting complaint was urinary incontinence (69%). Complete blood cell count, serum biochemistry profile and urine cytology results were non-specific. Six (46%) h...
Integrated proteomic and transcriptomic profiling identifies aberrant gene and protein expression in the sarcomere, mitochondrial complex I, and the extracellular matrix in Warmblood horses with myofibrillar myopathy.
BMC genomics    June 11, 2021   Volume 22, Issue 1 438 doi: 10.1186/s12864-021-07758-0
Williams ZJ, Velez-Irizarry D, Gardner K, Valberg SJ.Myofibrillar myopathy in humans causes protein aggregation, degeneration, and weakness of skeletal muscle. In horses, myofibrillar myopathy is a late-onset disease of unknown origin characterized by poor performance, atrophy, myofibrillar disarray, and desmin aggregation in skeletal muscle. This study evaluated molecular and ultrastructural signatures of myofibrillar myopathy in Warmblood horses through gluteal muscle tandem-mass-tag quantitative proteomics (5 affected, 4 control), mRNA-sequencing (8 affected, 8 control), amalgamated gene ontology analyses, and immunofluorescent and electron m...
Postmortem diagnoses of spinal ataxia in 316 horses in California.
Journal of the American Veterinary Medical Association    June 2, 2021   Volume 258, Issue 12 1386-1393 doi: 10.2460/javma.258.12.1386
Hales EN, Aleman M, Marquardt SA, Katzman SA, Woolard KD, Miller AD, Finno CJ.To determine period prevalences of postmortem diagnoses for spinal cord or vertebral column lesions as underlying causes of ataxia (spinal ataxia) in horses. Methods: 2,861 client-owned horses (316 with ataxia [ataxic group] and 2,545 without ataxia [control group]). Methods: The medical records database of the University of California-Davis Veterinary Medical Teaching Hospital was searched to identify horses necropsied between January 1, 2005, and December 31, 2017. Results were compared between the ataxic and control groups and between various groups of horses in the ataxic group. Period pre...
Behavioral and cardiac responses in mature horses exposed to a novel object.
Journal of animal science and technology    May 31, 2021   Volume 63, Issue 3 651-661 doi: 10.5187/jast.2021.e51
Lee KE, Kim JG, Lee H, Kim BS.This study aimed to investigate whether breed, sex, and age affected temperament differently (more or less neophobic) in mature horses during a novel object test. The study included Jeju crossbred (n = 12, age = 9.42 ± 4.57 y), Thoroughbred (n = 15, age = 10.73 ± 3.09 y), and Warmblood horses (n = 12, age = 13.08 ± 3.55 y) with the females (n = 22, age = 11.36 ± 4.24 y) and geldings (n = 17, age = 10.65 ± 3.66 y). Jeju crossbreds (Jeju horse × Thoroughbred) are valuable considering their popular usage in Korea, but limited studies have explored temperament of Jeju crossbred horses. A tra...
A comparative study of breed differences in the anatomical configuration of the equine vertebral column.
Journal of anatomy    May 15, 2021   Volume 239, Issue 4 829-838 doi: 10.1111/joa.13456
Spoormakers TJP, Veraa S, Graat EAM, van Weeren PR, Brommer H.The importance of the equine thoracolumbar vertebral column in orthopaedic disorders is well recognized and diagnostic imaging becomes more feasible, but little is known about variations in the anatomical configuration within breeds. In this descriptive post-mortem study, anatomical variations in three widely differing breeds: Warmblood horses, Shetland ponies and semi-feral Konik horses are described. The caudal cervical (C), thoracic (T), lumbar (L) and sacral (S) regions of the vertebral column of 30 Warmblood horses, 29 Shetland ponies and 18 Konik horses were examined using computed tomog...
Rein Tension Signals Elicit Different Behavioral Responses When Comparing Bitted Bridle and Halter.
Frontiers in veterinary science    May 7, 2021   Volume 8 652015 doi: 10.3389/fvets.2021.652015
Eisersiö M, Byström A, Yngvesson J, Baragli P, Lanata A, Egenvall A.When a rider maintains contact on the reins, rein tension will vary continuously in synchronicity with the horse's gait and stride. This continuous variation makes it difficult to isolate the rein tension variations that represent a rein tension signal, complicating interpretation of rein tension data from the perspective of horse-rider interaction. This study investigated (1) the characteristics of a rein tension signal and (2) horse response to a rein tension signal for backing, comparing pressure applied by a bit (bridle), or by a noseband (halter). Twenty Warmblood horses (10 young, 10 adu...
[Prevalence of health problems in midlife Swiss warm-blooded horses].
Schweizer Archiv fur Tierheilkunde    May 5, 2021   Volume 163, Issue 5 339-350 doi: 10.17236/sat00301
Altermatt N, Dolf G, Ramseyer A, Burger D, Gerber V.The breeding of a healthy horse is the basic requirement for optimal performance. This is also specifically stated in the breeding goal of the Swiss warmblood horse and should be achieved through a strict selection of the stallions. The aim of this retrospective study was to assess the current state of the population to optimize breeding. Data on the health status of Swiss warmblood horses in the age between 6 and 16 years (midlife) were collected by a telephone survey and analyzed descriptively. Following the heritability of the most common health problems were estimated. Data on 1,861 horses...
Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd.
Pathogens (Basel, Switzerland)    April 29, 2021   Volume 10, Issue 5 537 doi: 10.3390/pathogens10050537
Klouth E, Zablotski Y, Goehring LS.Equid herpesvirus type 1 (EHV-1) causes several outbreaks of abortion and/or equid herpesvirus-associated myeloencephalopathy (EHM) worldwide each year. EHM is of great concern, as permanent neurological gait anomalies can leave a horse unfit for future use. The study assesses the risk factors associated with the occurrence of EHM. During an unmitigated outbreak, 141 adult horses/ponies of several distinct breeds were evaluated-using multiple Bayesian logistic regression calculating the odds ratios for breed, age, and sex. In total, 33 of the 141 horses showed signs of EHM. Fjord horses and wa...
[Therapy of bullous pemphigoid in a Warmblood gelding].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    April 26, 2021   Volume 49, Issue 2 139-144 doi: 10.1055/a-1395-6307
Ehrmann C, Hartung S, Hirz M, Fey K.A 15-year-old Warmblood gelding was presented with multiple large, ulcerative, and crusty dermal lesions that had been existing for 4 years. Histopathology of a skin biopsy revealed cleft formation at the dermal-epidermal junction beneath the basal cells and above the basement membrane leading to the diagnosis of bullous pemphigoid. Immunosuppressive therapy with dexamethasone and azathioprine was initiated and after 14 weeks full remission of the ulcers was achieved. Scar tissue formation was evident in the areas of the formerly affected lesions. Following medication tapering over a perio...