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Cerebral arterial mapping in the equine brain: a detailed anatomical study.
Frontiers in veterinary science    June 2, 2026   Volume 13 1828754 doi: 10.3389/fvets.2026.1828754
Al Aiyan A, Abu Hayah S, Alnahdi AF, Alshamsi A, Alshebli H, Aleissaee S, Balan R.Detailed knowledge of the cerebral arterial system in equine brain is required for advancing neuroanatomical understanding and supporting the interpretation of neurological disorders. The equine cerebrum, characterized by extensive cortical organization and functional specialization, requires a continuous arterial blood supply; however, detailed information on its arterial anatomy remains limited. This study aimed to describe the arterial supply to the equine cerebrum, including the origin, branching patterns, and distribution of the major cerebral arteries. Unassigned: Ten adult horse heads w...
Research Trends and Emerging Frontiers in Racehorse Genetics: A Bibliometric Analysis.
Animals : an open access journal from MDPI    June 2, 2026   Volume 16, Issue 11 1705 doi: 10.3390/ani16111705
Huang Q, Yao X, Yang X, Wang T, Li X, Shan D, Su Y, Wang J.The global horse racing industry relies heavily on elite breeding. Therefore, a molecular understanding of athletic traits is crucial for the industry's advancement. This study utilized Bibliometrix, VOSviewer, and CiteSpace to conduct a comprehensive bibliometric analysis of 869 publications in the Web of Science Core Collection (2011-2025), decoding the academic landscape and evolutionary trajectory of equine genetics. The results indicate a significant upward trend in academic output since 2019, with the United States, South Korea, and the United Kingdom emerging as the primary contributors...
Ovum pick-up in mares: Evidence review and best practice recommendations using a modified GRADE approach.
Theriogenology    June 2, 2026   Volume 264 118021 doi: 10.1016/j.theriogenology.2026.118021
Lewis N, Dini P, Spanner J, Claes A, De Grauw J, Morganti M, Daels P, Cuervo-Arango J.Ovum pick-up (OPU) is a procedure that is now performed in mares worldwide to harvest oocytes for in vitro embryo production. There is a lack of consensus surrounding best practices for various procedural elements of the technique and recently there has been an increasing focus on the welfare aspects of the procedure. Our objective was to summarize current practice and to develop guidelines for OPU in the mare, using a modified GRADE approach to optimize efficiency and mare welfare. Published evidence on various aspects of the procedure was compiled, and to supplement the relative lack of publ...
Genetic variability and associations of Trakehner and other horse populations in Lithuania.
Archives animal breeding    June 2, 2026   Volume 69, Issue 2 323-336 doi: 10.5194/aab-69-323-2026
Račkauskaitė A, Šveistienė R, Razmaitė V, Jatkauskienė V, Marašinskienė Š.To obtain genetic parameters relevant for the management of animal genetic resources, this study provides a comparative characterization of the Trakehner (TRAK) horse population in relation to four other horse populations maintained in Lithuania - Arabian (ARAB), Baltic Warmblood (BW), Lithuanian Warmblood (LW), and Zemaitukai (ZEM). These populations represent diverse histories, selection goals, and breeding practices. Pedigree data ( 22 666) and parentage verification genetic data based on blood group markers ( 1293) were used to evaluate genetic diversity, population structure, and inter-...
Cross-protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies.
Equine veterinary journal    June 2, 2026   doi: 10.1002/evj.70200
Paillot R, Newton JR, Gonzalez Medina S, Frosth S, Frykberg L, Flock M, Guss B, Flock JI, Waller AS.Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objective: To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with Strangvac®, a vaccine against Streptococcus equi subspecies equi, conferred cross-protection. Methods: Retrospective analysis of a double-blinded placebo-controlled study involving 32 ponies (16 vaccinates and 16 placebo controls) that experienced a natural episode of respiratory...
Molecular prevalence of equine herpesvirus type 1 and equine herpesvirus type 4 in thoroughbred and Arabian horse facilities in Türkiye.
Acta veterinaria Hungarica    June 2, 2026   004.2026.01202 doi: 10.1556/004.2026.01202
Ekİncİ G, Tİmur MC, Mete A, Altınbay K, Denİz Ö, Derellİ FM, Çeşme GS, Tüfekçİ E, Onmaz AC, Güneş V, Çİtİl M, Keleş İ....Equine herpesvirus-1 and -4 are contagious viruses causing respiratory disease and reproductive losses in horses. This study aimed to determine the prevalence of EHV-1 and EHV-4 in eight Turkish stud farms using RT-PCR analysis of nasal secretions, uterine fluids and aborted foal tissues. Deep nasal swabs were collected from 443 horses showing acute-onset fever and/or clinical signs of respiratory disease. Additionally, uterine swabs and tissue samples (lung, liver, spleen, thymus, kidney, heart) were obtained from 152 abortion cases. Among symptomatic horses, EHV-1 DNA was found in 2 cases (0...
Infection by Strongylus edentatus and Strongylus vulgaris in a warmblood crossbred foal in Ontario.
The Canadian veterinary journal = La revue veterinaire canadienne    June 1, 2026   Volume 67, Issue 6 663-669 
Trokoz A, Sjolin E, Lejeune M, Peregrine AS, Borkowski E.A 6-month-old warmblood-cross filly was presented to the Ontario Veterinary College Large Animal Hospital (Guelph, Ontario) because of acute profuse diarrhea unresponsive to treatment and severe wasting. The filly progressed to obtundation over 4 d and was euthanized. Postmortem examination revealed multifocal hemorrhage within the extraperitoneal fascia and diaphragm with intralesional, 4-centimeter-long, white nematodes. In addition, verminous arteritis of the cranial mesenteric artery, right colic artery thrombosis with segmental colonic infarction, ulcerative colitis, and segmental fibrino...
Vitrification of in vivo produced equine embryos: Size really does matter!
Journal of equine veterinary science    June 1, 2026   Volume 164 106032 doi: 10.1016/j.jevs.2026.106032
Wilsher S.Vitrification rather than slow-freezing has become the method of choice for the cryopreservation of in-vivo produced embryos. It is a simple technique that does not require a programmable freezing machine and relies chiefly on placing the embryo on a surface, rather than within a straw, in a small volume of vitrification solution to achieve extremely rapid cooling rates. However, in the field of equine embryo vitrification size truly does matter. Methodologies for both vitrification and warming prior to transfer are largely dictated by the size of the embryo. Since embryo size is directly rela...
Use of computer-assisted tomography for diagnosis and standing surgical reduction of progressive ethmoidal hematoma in a mare.
The Canadian veterinary journal = La revue veterinaire canadienne    June 1, 2026   Volume 67, Issue 6 626-632 
Lee S, Lee EB, Kim T, Jung JY, Kim JH, Seo JP.Progressive ethmoidal hematoma (PEH) is a rare, nonneoplastic mass occurring in the sinonasal passages of horses. An 11-year-old, pregnant Thoroughbred mare was presented with a history of intermittent nasal discharge and stertorous respiration. On examination, radiography revealed increased opacity in the sinus and nasal cavities and endoscopy identified a mass emerging from the left ethmoidal turbinate. Computed tomography (CT) showed the range and origin of the mass, indicative of PEH. A standing frontonasal flap was made under sedation, following temporary tracheostomy to secure the airway...
Short-interval longitudinal analysis of immune cell dynamics in heavy draft foals after colostrum intake.
The Journal of veterinary medical science    June 1, 2026   Volume 88, Issue 8 1134-1143 doi: 10.1292/jvms.26-0023
Yoshida S, Takeyama A, Maeda Y, Nambo Y.Maternal cells and antibodies are present in equine colostrum, but their relationship with immune cells in foals after colostrum ingestion remains unclear. This study longitudinally analyzed immune cells in the peripheral blood of neonatal foals at short intervals and investigated their relationship with colostral immune cells. Eleven clinically healthy draft mares and their foals were examined. Foal blood was collected before colostrum intake (0 hr) and at 2-3, 6, 12, 36-48 hr, and 3 and 7 days after ingestion. Mare blood and milk (0, 36-48 hr; 0 hr milk defined as colostrum) were also collec...
Roux-en-Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70203
Gandini M, Bolz N, Czech C, Hartman M, Giusto G.Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can restore patency but may lead to postoperative complications. Objective: To describe the presentation, surgical management, and postoperative outcome of two horses-an adult and a foal treated with Roux-en-Y gastrojejunostomy combined with a side-to-side jejunojejunostomy (...
Renal Perfusion in Healthy Horses: A Feasibility Study With Contrast-Enhanced Ultrasound. This study assessed the feasibility of contrast-enhanced ultrasound (CEUS) for evaluating renal perfusion in horses and compared perfusion parameters between age groups. In a prospective study, eight healthy horses were divided into young (3-5 years, n = 4) and old (16-17 years, n = 4) groups. All animals underwent B-mode, Doppler ultrasonography, and CEUS of the right kidney after an intravenous bolus of SonoVue (0.02 mL/kg). Qualitative analysis assessed contrast kinetics, whereas quantitative parameters (peak intensity, time to peak [TP], area under the curve, and wash-out time) were o...
Embryo developmental kinetics and vitrification in relation to pregnancy outcome, foaling percentage and foal sex.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70197
Peere S, Dewulf M, Van den Branden E, Papas M, Broothaers K, De Coster T, Briote I, Hedia M, Angel-Velez D, Hoogewijs M, Govaere J, Smits K.While fast in vitro embryo development has been associated with improved outcomes, the relationships of slow in vitro embryo development and vitrified versus fresh in vitro produced (IVP) embryo transfer to foaling percentage and foal sex are less explored. Objective: To determine the relationships of (1) day of blastocyst formation (D7-11 after intracytoplasmic sperm injection (ICSI)) and (2) vitrification and warming method (one- and three-step) versus fresh transfer with pregnancy, early pregnancy loss (EPL), foaling percentage and foal sex. Methods: Retrospective clinical study. Methods: B...
Oclacitinib for Controlling Pruritus and Associated Skin Lesions in 16 Horses With Allergic Dermatitis.
Veterinary dermatology    May 31, 2026   doi: 10.1111/vde.70091
Nuchprayoon N, Maneephan P, Tovanakasame N, Kampang C, Jandee P, Sangsuriya P, Tunhikorn M.Oclacitinib is a Janus kinase inhibitor approved for the treatment of pruritus associated with allergic dermatitis in dogs and may be effective in horses. Objective: To evaluate the efficacy of oclacitinib in reducing pruritus and skin lesions in horses with allergic dermatitis. Methods: Sixteen horses aged ≥ 18 months. Methods: Horses received oclacitinib at 0.25 mg/kg orally once daily for 21 days. Changes in haematological and biochemical parameters were measured on Day (D)0 and D21. The owners were instructed to evaluate the horses using the pruritus Visual Analog Scale (PVAS) on...
Cheek tooth extraction in geriatric versus non-geriatric horses.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70199
Mair E, Nekouei O, Trummer-Schug P, Haralambus R, Biermann NM.Age-related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population. Objective: To describe clinical features, treatments, complication rates and short-term outcomes of horses undergoing oral cheek tooth extraction and treatment of odontogenic sinusitis, and to compare findings between geriatric and non-geriatric horses. Methods: Retrospective analysis of clinical...
Development of a prognostic scoring system for systemic inflammatory response syndrome in donkeys.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70202
Barnabé MA, Bamford NJ, Elliott J, Chang YM, Rickards K, Menzies-Gow NJ.Systemic inflammatory response syndrome (SIRS) is associated with increased mortality in horses with gastrointestinal (GI) disease. However, there are no data relating to naturally occurring SIRS in donkeys. Objective: To determine SIRS frequency in donkeys with GI disease. To develop a donkey-specific prognostic SIRS score. Methods: Retrospective case series. Methods: Clinical records from donkeys presenting with GI disease in two independent cohorts (development cohort: n = 400, UK; validation cohort: n = 36, Australia) were reviewed. Age, sex, heart rate, respiratory rate, rectal te...
Laser neoureterocystostomy to treat ectopic ureters.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70201
Smith C, Parente EJ.Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity. Identification of a minimally invasive, effective technique would significantly improve prognosis. Objective: To describe the procedure and outcomes of cystoscopic guided laser neoureterocystostomy in three fillies. Methods: Case series. Methods: Retrospective review of three cases treated wi...
Prevalence of cardiac arrhythmias in poorly performing horses.
Open veterinary journal    May 31, 2026   Volume 16, Issue 5 2961-2969 doi: 10.5455/OVJ.2026.v16.i5.39
Aliraqi OM, Albadrani BA.Electrocardiogram abnormalities are common in racehorses and can affect performance. Unassigned: This study aimed to analyze the results of electrocardiographic problems and measure the frequencies of various cardiac arrhythmias. Unassigned: This cross-sectional study was conducted between September 2023 and August 2024. Standard electrocardiographic recordings were obtained from all horses, and cardiac troponin levels were measured. Out of the 114 poorly performing adult horses, 10 cases without arrhythmia were considered the control group. Seventy-four horses (64.9%) had at least one type of...
Pathology of sudden death in racehorses: a review. Uzal FA, Asin J, Diab S, Henderson E, Engiles JB, Kennedy L, Schild C.Sudden death (SD) is the second most important syndrome associated with death in racehorses. The cause of SD in a large number of horses remains undetermined, and, in many of these cases, causes are not found by gross or microscopic postmortem examinations. Among the known causes of SD are traumatic injuries, including fractures of skull, neck, and pelvis; intoxications (e.g., anticoagulant rodenticides); and others. For many cases of SD in which no significant lesions are found, heart failure, probably associated with arrhythmias, is suspected. Precise phenotypic characterization of SD in hor...
Integrative Metabolomic and Echocardiographic Profiling Reveals Metabolic-Cardiac Structural Coupling in Yili Horses During Incremental Exercise.
Animals : an open access journal from MDPI    May 30, 2026   Volume 16, Issue 11 1672 doi: 10.3390/ani16111672
Chang X, Peng J, Zhang Z, Zhai M, Chu H, Yao R, Luo P, Yao X, Ren W, Zeng Y.This study integrated echocardiography with widely targeted metabolomics to decipher how plasma metabolic dynamics couple with cardiac geometry in Yili horses during incremental treadmill exercise. Nine speed-type horses underwent a graded exercise test (6% incline; 0 to 9 m/s). Jugular venous blood samples collected at rest (0 m/s) and at 3, 5, 7, and 9 m/s were profiled by LC-MS, and Pearson correlation analysis was applied to relate differentially expressed metabolites (DEMs) to twenty echocardiographic structural indices. A core set of 314 shared DEMs (124 upregulated, 190 downregulated) w...
Estimating the economic value of working donkeys in Ethiopia.
Preventive veterinary medicine    May 30, 2026   Volume 254 106926 doi: 10.1016/j.prevetmed.2026.106926
Asteraye GB, Jobling R, Jemberu WT, Pinchbeck G, Knight-Jones TJD, Chaters GL, Rushton J.There is limited empirical evidence on the quantitative economic contribution of donkeys to livelihoods, leading to their undervaluation and exclusion from policy. Here an enterprise budget analysis is embedded within a stochastic dynamic population model for three production systems in Ethiopia to evaluate system inputs, outputs and the economic contribution of donkeys. The model was parameterised using data from household surveys, focus group discussions and key informant interviews, supplemented by literature. The economic value of donkeys' (unpaid) homestead and agricultural services was e...
Evaluation of two point-of-care molecular diagnostic platforms for rapid detection of equine Hendra virus.
Veterinary and animal science    May 30, 2026   Volume 33 100713 doi: 10.1016/j.vas.2026.100713
Hulse L, Izzard L, Nagendrakumar SB, Colling A, Underwood D, Driver L, Williams DT, Ahern B.Hendra virus (HeV) is a lethal zoonotic pathogen endemic to eastern Australia, posing significant risks to equine and human health. Rapid field detection of HeV enables timely intervention and outbreak management. This study evaluated candidate point-of-care (POC) molecular diagnostic platforms for HeV detection in equine samples: including a loop-mediated isothermal amplification (DARQ RT-LAMP) assay and real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR). Comparative analytical evaluation demonstrated that RT-qPCR exhibited superior analytical sensitivity relativ...
Herd-level occurrence and spread of Theileria equi and its associated ticks on an Austrian horse farm.
Veterinary parasitology, regional studies and reports    May 30, 2026   Volume 72 101509 doi: 10.1016/j.vprsr.2026.101509
Pikalo J, Hartl B, Stimac I, Barogh BS, Fuehrer HP, Joachim A.Equine piroplasmosis (EP) is a tick-borne disease caused by the blood parasites Theileria equi, Theileria haneyi, and Babesia caballi transmitted primarily by hard ticks (Ixodidae). The clinical courses of EP range from asymptomatic to severe, and chronic infections for several years support the transmission among hosts. Methods: Over a period of two years, blood and fecal samples were taken from horses (n = 18) on a single farm in eastern Austria, starting with the first confirmed case of T. equi infection. Hard ticks (n = 1525 of Ixodes ricinus, Dermacentor reticulatus and Haemaphysalis ...
Management of Equine Post-Extraction Cheek Tooth Alveoli: Application of Alveolar Plugs.
Animals : an open access journal from MDPI    May 30, 2026   Volume 16, Issue 11 1678 doi: 10.3390/ani16111678
Śmich J, Górski K, Maśko M, Borowska M, Turek B, Domino M.Preservation of dentition remains the primary goal of equine dentistry; however, cheek tooth extraction is required in cases of severe dental pathology. Following tooth extraction, management of the post-extraction alveolus remains a significant clinical challenge due to its large size and susceptibility to contamination with feed material and bacteria. To mitigate these risks, alveolar plugs are commonly used to protect the alveolus, stabilize the blood clot, and support granulation tissue formation. This review summarizes the current case reports and research articles regarding the use of al...
Efficacy of 0.5% Tretinoin in the Treatment of Equine Aural Plaques.
Veterinary dermatology    May 29, 2026   doi: 10.1111/vde.70090
de Mattos FS, Conceição LG, Schuartz YGH, Silva VRM, Fidélis CF, Mansur FC, Teixeira CS, Sancler-Silva YFR, Oliveira-Filho JP, Borges AS....Equine aural plaques are a benign form of auricular papillomatosis caused by equine papillomavirus. Despite the efficacy of 5% imiquimod cream, a marked local reaction is frequently observed during therapy, often requiring sedation before application. Objective: The aim of this study was to evaluate the efficacy and potential adverse effects of 0.5% topical tretinoin in the treatment of equine aural plaques. We hypothesised that tretinoin would be effective, with fewer adverse effects compared to imiquimod. Methods: The study included 10 horses of both sexes, aged between 7 months and 15 y...
Association Between Vaquejada Practice and Biomarkers of Oxidative Stress, Inflammation, and Muscle Damage in Quarter Horses.
Veterinary sciences    May 29, 2026   Volume 13, Issue 6 531 doi: 10.3390/vetsci13060531
Nascimento RCMD, Guedes EAB, Silva RBD, Cerqueira ITI, Freire CCDS, Câmara DR, Moura FA, Escodro PB, Goulart MOF.Vaquejada (VQ) is a traditional Brazilian sport demanding high performance from Quarter Horse (QH) athletes. This study aimed to identify modifications in hematological, biochemical, inflammatory, and oxidative stress biomarkers associated with VQ training, comparing conditioned and non-conditioned horses. Blood samples were collected at rest from 70 healthy QH horses: 60 athletes (VQ-conditioned athlete group-AG) and 10 sedentary controls (breeding horses-CG). Using Linear Mixed Models alongside comprehensive hematological and biochemical analyses, the study found that AG horses exhibited an ...
Equine-assisted coaching in formerly incarcerated men with histories of substance abuse: a 12-week exploratory study of anger regulation, quality of life, human-horse synchrony, and equine behavior.
Frontiers in psychology    May 29, 2026   Volume 17 1832096 doi: 10.3389/fpsyg.2026.1832096
Griffioen RE, Haven-Pross SC, Verkuil H.Equine-assisted interventions are increasingly used as complementary approaches to support psychosocial functioning, yet empirical evidence in justice-involved populations with histories of substance abuse remains limited. The present exploratory quantitative study examined the effects of a 12-week equine-assisted coaching program on anger regulation, quality of life, and human-horse synchrony in formerly incarcerated men, while also monitoring equine behavioral responses from a One Health perspective. Eleven male participants residing in a residential reintegration facility in the Netherlands...
Do Polish Konik Horses Find Soaked Hay to Be Palatable?
Animals : an open access journal from MDPI    May 29, 2026   Volume 16, Issue 11 1663 doi: 10.3390/ani16111663
Tkaczyk E, Gazda IE, Humięcka M, Łuszczyński J, Basińska K, Kaczmarek B, Barłowska J, Tkaczyk P, Janczarek I.Frequently, equine diseases necessitate the moistening or soaking of hay for the horses. It was assumed that this treatment would not reduce the willingness of the Polish Konik horses with low nutritional requirements to consume the hay. Furthermore, it was believed that moistening would increase the palatability of this feed. The aim of this study was to determine time and frequency parameters and the amount of unconsumed dry, moist, or soaked hay. The research material comprised 12 Polish Konik horses consuming either 1 kg of dry hay, 2.1 kg of moist hay, or 3.3 kg of soaked hay on three sub...
Comparative analysis of mesenchymal stromal cells derived from ovarian follicular aspirates of young and aged mares.
Theriogenology    May 29, 2026   Volume 263 118003 doi: 10.1016/j.theriogenology.2026.118003
Muñoz-García CC, Soriano-Campos MP, Luis-Calero M, Gallardo-Soler A, González-Fernández L, Macías-García B.Mesenchymal stromal cells from equine ovarian follicular aspirates represent a promising source for cell-based therapies. However, the age of the donor mare may alter their biological properties and therapeutic potential. This study aimed to evaluate the effect of age on MSCs from ovarian follicular aspirates of young (< 10 years, n = 5) and aged (≥ 18 years, n = 5) mares. MSCs were isolated, expanded, cryopreserved at passage 3, and subsequently thawed to evaluate proliferation, immunophenotype, differentiation capacity, and gene expression profiles. Proliferation rates, total cel...
Whole Genome Data Uncover the Complex Origins of Polish Konik Horses.
Animals : an open access journal from MDPI    May 29, 2026   Volume 16, Issue 11 1669 doi: 10.3390/ani16111669
Musiał AD, Ropka-Molik K, Szmatoła T, Podstawski P, Finno CJ, Bieniek A, Wilczyński J, Stefaniuk-Szmukier M.Polish Konik is a native horse breed from Poland often regarded as living descendants of the extinct Tarpan, which has been crucial to the breed's conservation status and cultural importance. To evaluate Polish Konik origins, we sequenced 12 whole genomes and compared them with 148 horse genomes, including those of modern breeds, ancient Polish horses, Przewalski horses, and the Tarpan. The ADMIXTURE results showed that Polish Konik is dominated by a single ancestral component, which is also common among ancient Polish samples and several primitive breeds. The PCA places Polish Konik in a comp...