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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Effect of neonatal rib fracture repair on racing and sales performance in Thoroughbreds.
Equine veterinary journal    July 28, 2026   doi: 10.1002/evj.70218
Young LM, Courtney ER, Freeland RB.The racing outcome of horses that have undergone surgical repair of neonatal rib fractures is not well documented. Objective: To evaluate the impact of surgical repair of neonatal rib fractures on subsequent sales and racing performance in Thoroughbreds. Methods: Retrospective cohort study. Methods: Medical records of neonatal Thoroughbreds that underwent surgical repair of rib fractures at a referral hospital between 2014 and 2025 were reviewed. Sales and racing data were obtained from publicly available databases. Outcomes assessed included sale price at weanling and yearling sales, total ca...
Ceratohyoidectomy for Management of Unilateral and Bilateral Temporohyoid Osteoarthropathy: Long-Term Outcome in 33 Equids.
Animals : an open access journal from MDPI    July 28, 2026   Volume 16, Issue 15 2318 doi: 10.3390/ani16152318
McCrary HS, Stewart HL, Davis JG, Garcia-Lopez JM, Bubeck KA.Temporohyoid osteoarthropathy is a disease affecting the temporohyoid joint in equids caused by local inflammation and/or degeneration, leading to neurological deficits ranging from mild signs that affect performance to significant, acute neurological deficits such as facial nerve paralysis or vestibular signs. Multiple surgical treatment options are available, and while treatment has historically been performed unilaterally on the side of the clinical signs, advances in diagnostic imaging have highlighted the occurrence of bilateral disease of the temporohyoid joints, warranting evaluation of...
A Leptospirosis Outbreak in a Riding Stable in Central Italy.
Veterinary sciences    July 28, 2026   Volume 13, Issue 8 750 doi: 10.3390/vetsci13080750
Leptospirosis is a widespread zoonotic disease of major concern for both veterinary and public health. In horses, it is associated with equine recurrent uveitis, a painful condition that may lead to blindness and affects approximately 10% of the global horse population. In May 2025, following the occurrence of three uveitis cases in a riding stable in Central Italy, 94 equine blood samples were collected and tested using the microscopic agglutination test (MAT) for spp. Antibody titres against serogroup Icterohaemorrhagiae were detected in 68 horses (72.4%). An on-site investigation was condu...
Malignant melanoma with marked epithelial hyperplasia presenting as a papillomatous mass on the prepuce of a horse.
New Zealand veterinary journal    July 27, 2026   1-4 doi: 10.1080/00480169.2026.2692593
Munday JS, Panizzi L, Pagé AS, Gans C, Grant KA, Smedley RC.No abstract available
SURVIVAL ON THE MARGINS: NICHE PARTITIONING AND DENSITY-DEPENDENT SPATIAL DISTRIBUTION OF EQUINE CYATHOSTOMINS.
The Journal of parasitology    July 27, 2026   Volume 112, Issue 4 426-434 doi: 10.1645/26-35
Ripley NE, Gravatte HS, Reinemeyer CR, Nielsen MK.Habitat preferences of gastrointestinal nematodes are well-documented in small hosts, but equine cyathostomin diversity has largely been characterized only at farm or regional levels. While organ-level site preferences are known, within-organ spatial distributions remain unexplored. We investigated the longitudinal and radial distribution of adult cyathostomins within the large-intestinal lumen. Intact large intestines from 5 Shetland ponies were frozen post-necropsy and transected into 4-cm sections. Three micro-habitat samples (2.5 cm diameter) were collected per section. We recovered 2,444 ...
Plasma Homocysteine Concentrations in Horses with Left-Sided Valvular Heart Disease.
Animals : an open access journal from MDPI    July 26, 2026   Volume 16, Issue 15 2307 doi: 10.3390/ani16152307
Egli P, Williams Louie E, Stirn M, van Loon G, Decloedt A, Schwarzwald CC, Mitchell KJ.In human medicine, homocysteine, a sulfur-containing amino acid, is used as a biomarker reflecting endothelial dysfunction, inflammation, thrombogenesis, oxidative stress and cardiovascular disease. An automated enzyme-cycling assay for homocysteine, established for humans, has been validated and reference ranges have been created for horses. In this study the homocysteine assay was further evaluated by assessing short-term stability (whole blood and plasma samples stored at 4 °C and room temperature for 24 h), long-term stability (two years), the effect of different anticoagulants (lithium h...
Three-year evaluation of anthelmintic treatment efficacy against equine strongyles in France using FECRT.
International journal for parasitology. Drugs and drug resistance    July 24, 2026   Volume 31 100663 doi: 10.1016/j.ijpddr.2026.100663
Reduced anthelmintic efficacy against strongyles in equids is a widespread concern, but up-to-date field data are scarce. The aim of this study was to evaluate, over a three-year period, the efficacy of the anthelmintic (AH) molecules available in France (fenbendazole, pyrantel, ivermectin and moxidectin) against strongyles in equids using faecal egg count reduction tests (FECRTs). A total of 104 complete FECRTs (i.e., required sample size reached) were conducted in 98 groups, involving 749 equids kept in 70 facilities. Fenbendazole-resistant populations were detected in 8/9 groups (89%) from ...
Molecular detection of African horse sickness virus from selected areas in Ethiopia.
Veterinary and animal science    July 24, 2026   Volume 34 100782 doi: 10.1016/j.vas.2026.100782
Esey DF, Waktole H, Gelaye E, Alene DH, Minale HA.Equines are vital to global economies and support millions of livelihoods. However, their productivity and welfare are severely hindered by infectious diseases such as African Horse Sickness, which causes major socio-economic losses in Ethiopia. A cross-sectional study was conducted from November 2022 to May 2023 to isolate and detect African horse sickness virus in equines across epidemic areas of Ethiopia. In total, 30 blood samples and 2 tissue representative specimens were aseptically collected from clinically sick and recently dead animals and transported under cold chain to the National ...
Effects of TECAR Therapy on Body Surface Temperature and Longissimus Dorsi Muscle Tone in Thoroughbred Racehorses: A Pilot Study.
Animals : an open access journal from MDPI    July 24, 2026   Volume 16, Issue 15 2300 doi: 10.3390/ani16152300
Grzegorczyk W, Soroko-Dubrovina M, Dobrowolski M, Grabska D, Dudek KD.Capacitive and resistive electric transfer (TECAR) therapy is increasingly used in equine physiotherapy; however, objective evidence regarding its immediate effects on equine back muscles remains limited. This pilot study aimed to evaluate the effects of TECAR therapy on body surface temperature and muscle tone of the longissimus dorsi muscle in Thoroughbred racehorses. A randomized, single-blinded experimental study was conducted in 20 clinically healthy Thoroughbred racehorses aged 2-3 years. Horses were randomly assigned to either a TECAR treatment group ( = 10) or a sham-treatment control ...
The Transcriptomic and Proteomic Molecular Signatures of Equine Multiple-System Neuropathy (Grass Sickness).
Cells    July 24, 2026   Volume 15, Issue 15 1328 doi: 10.3390/cells15151328
Summers KM, Karagianni AE, Fernandez PL, Beard PM, Pirie RS, Keen JA, Wishart TM, McGorum BC.Equine grass sickness (EGS or equine dysautonomia) is a predominantly fatal multi-system neuropathy affecting grazing horses, likely caused by a neurotoxic phospholipase A2 (nPLA2) derived from a plant or microorganism. We studied neuronal tissue gene and protein expression patterns in EGS to elucidate the possible mechanisms of neurotoxicity and neurodegeneration. Tissue from the cranial cervical ganglion of eight EGS horses and six controls was examined histologically and used for transcriptomic analysis. These transcriptomic data were compared with previously published EGS-related proteomic...
The effect of fenugreek (Trigonella foenum-graecum) on stallion spermatozoa motility and vitality in vitro.
Veterinary research communications    July 24, 2026   Volume 50, Issue 5 482 doi: 10.1007/s11259-026-11424-9
Vanivska K, Kollárová I, Mezeyová I, Galovičová L, Dianová L, Halo M, Slanina T, Lenický M, Greń A, Reisenauer R, Massányi P.This study evaluated the effects of Trigonella foenum-graecum L. (fenugreek) seed extract on stallion spermatozoa quality in vitro, focusing on motility, vitality, and functional competence. In vitro spermatozoa analyses showed that fenugreek seed extract did not demonstrate overt cytotoxicity under the tested conditions: S1 = 1562 µg/mL; S2 = 781 µg/mL; S3 = 390.5 µg/mL; S4 = 195.25 µg/mL; S5 = 97.62 µg/mL; S6 = 48.81 µg/mL; S7 = 24.40 µg/mL. Computer-assisted semen analysis (CASA) revealed a concentration- and time-dependent Treatment × Time interac...
Correction to: Seroprevalence and risk factors of African horse sickness in equines in central Gondar, Ethiopia.
Veterinary research communications    July 23, 2026   Volume 50, Issue 5 476 doi: 10.1007/s11259-026-11406-x
Yehulashet AA, Wondmnew F, Abat AS, Alamerew EA, Birhan M, Tafere FA, Malede BA, Sechu A, Mersha AC, Tsehay EM, Temesgen AB.No abstract available
Vasopressin stimulation testing in hospitalized foals.
Journal of veterinary internal medicine    July 23, 2026   Volume 40, Issue 4 aalag149 doi: 10.1093/jvimsj/aalag149
Albrecht M, Perez J, Wong D, Browne N, Burns T, Stevens ME, Dembek K.Hypothalamic-pituitary-adrenal gland axis (HPAA) dysfunction impairs survival and can be diagnosed with an arginine vasopressin (AVP) stimulation test. Objective: Adrenocorticotropic hormone (ACTH) and cortisol response to an AVP stimulation test will be attenuated in hospitalized foals compared to healthy foals and associated with severity of disease. Methods: Fifteen healthy and 45 hospitalized foals: 19 septic, 26 sick non-septic (SNS). Methods: A prospective, observational case-control design was utilized to assess HPAA function and compare corticotropin-releasing hormone, ACTH, and cortis...
An observational study evaluating the environmental impact of equine arthroscopy.
The Veterinary record    July 23, 2026   doi: 10.1002/vetr.70981
White K, Hillen F, Hird J, Byrne C, Shipman R, Taylor P.Human pressures on Earth's life‒support systems have exceeded multiple planetary boundaries, highlighting the need for sectors, including veterinary healthcare, to reduce environmental impacts. Methods: A prospective convenience sample of 10 horses undergoing arthroscopy at a UK equine hospital between January and March 2025 was studied. Data were collected on anaesthesia, volatile capture, pharmaceuticals, single-use consumables, waste, building energy and travel by horses and staff. Carbon emissions (kgCOe) were calculated using published conversion factors. A hybrid methodology combined b...
High-Throughput Equine Plasma Profiling Using Laser-Assisted Rapid Evaporative Ionisation Mass Spectrometry.
Journal of mass spectrometry : JMS    July 23, 2026   Volume 61, Issue 8 e70077 doi: 10.1002/jms.70077
Molnár A, Arko M, Troha K, Marton A, Tauber B, Iglič A, Balogh GT, Balog J, Hočevar M, Kos VK, Battelino S, Kralj-Iglič V, Schlosser G.Remnants of erythrocyte removal from blood constitute therapeutic plasma-a water-based solution containing mainly platelets, extracellular vesicles (EVs), protein and lipid complexes and ions. Plasma-based therapies, including their use to accelerate wound healing in human and animal patients, are increasingly gaining prominence in regenerative medicine; however, methods for the optimal preparation of individual plasma are still under development. Rapid and accurate analysis of plasma composition is essential for the development of therapeutic applications and for ensuring the quality of plasm...
Tick-borne pathogens in a nature reserve area in the Netherlands: serological and molecular assessments in large herbivores and Ixodes ricinus ticks.
Ticks and tick-borne diseases    July 23, 2026   Volume 17, Issue 4 102686 doi: 10.1016/j.ttbdis.2026.102686
Marcelino I, Vriens R, Hakze-van der Honing RW, Lesiczka P, de Vries A, Graham H, Streng K, Cornelissen P, Uiterwijk M, Monti G, Sprong H....Ticks are vectors of a wide range of pathogens, relevant to both veterinary and public health. Although tick surveillance is frequently conducted in the Netherlands, data on tick-borne pathogens in free-living herbivores remains limited, leaving the impact of these pathogens on animal health poorly understood. This study aimed to characterise tick species and determine seroprevalence and infection prevalence of selected tick-borne pathogens in large herbivores at the Oostvaardersplassen nature reserve and questing ticks collected in the area. Between September 2023 and December 2024, blood was...
Penile and preputial pythiosis in Saudi Arabian horses: clinicopathological features and surgical outcomes.
Frontiers in veterinary science    July 22, 2026   Volume 13 1872270 doi: 10.3389/fvets.2026.1872270
El-Shafaey ES, Salem M, Awadin W, Mosbah E, Rizk MA, Meligy AMA, Shousha S, Aljazzar A, El Sebaei MG.Pythiosis, caused by , is a chronic granulomatous disease of horses characterized by invasive, ulcerative, and pyogranulomatous cutaneous lesions. Involvement of the external genitalia is uncommon and remains poorly characterized, particularly regarding environmental exposure and treatment outcomes. This study aimed to describe the epidemiological pattern, clinicopathological features, diagnostic findings, and surgical outcomes of penile and preputial genital pythiosis in a hospital-presented horse cohort. Unassigned: A retrospective study was conducted on 123 horses presented with cutaneous u...
Longitudinal and spatial declines in equine Hendra virus vaccination despite continued risk.
Vaccine    July 22, 2026   Volume 88 128937 doi: 10.1016/j.vaccine.2026.128937
Linnegar B, McCallum H, Peel AJ.Hendra virus is an emerging zoonosis endemic to Australia with high fatality of infection in horses and humans. The role of infected domestic horses as amplifying bridge hosts for onward transmission to humans led to the creation of an equine vaccine as a One Health solution against spillover. Despite the risk this disease represents, previously reported equine vaccination rates were low. This study explored vaccination trends between 2012 and 2023 at fine spatial scales and identified demographic and ecological predictors of vaccination against emerging zoonoses. Over 1 million doses of Equiv...
Intratumoral para-toluenesulfonamide as a tumor-ablative therapy for equine cutaneous tumors: a case series of three horses.
Veterinary and animal science    July 21, 2026   Volume 34 100777 doi: 10.1016/j.vas.2026.100777
Lo HC, Yan-Der H, Chang PL, Lin MY, Kee S.Equine neoplasia, including sarcoids, melanomas, and squamous cell carcinomas, presents therapeutic challenges due to recurrence and limitations of conventional treatments. Para-toluenesulfonamide (p-TLS) is a tumor-ablating agent that is associated with localized tumor necrosis and subsequent lesion resolution. It has been evaluated in human clinical settings as an intratumoral treatment of malignant airway obstruction caused by non-small cell lung cancer. This study aimed to describe the clinical outcomes and tolerability of intratumoral p-TLS in equine neoplasia. Three equine cases, includi...
Correction: Review: Genomic insights into the adaptive traits and stress resistance in modern horses.
Stress biology    July 20, 2026   Volume 6, Issue 1 50 doi: 10.1007/s44154-026-00327-z
Jafari H, Abebe BK, Cong L, Ahmed Z, Zhaofei W, Sun M, Muhatai G, Chuzhao L, Dang R.No abstract available
Evaluation of the Brix refractometer for diagnosing the failure of transfer of passive immunity in 12-h-old foals.
Acta veterinaria Hungarica    July 20, 2026   004.2026.01271 doi: 10.1556/004.2026.01271
Akköse M, İnal Ş, Karabulut E, Yılmaz İÇ, Yağlıcı A, Kuzhan M, Özbeyaz C, Kaya U, Çam M.Failure of transfer of passive immunity (FTPI) is the most important cause of sepsis and mortality in neonatal foals. Unassigned: This study aimed to evaluate the performance of the digital Brix refractometer for the diagnosis of FTPI in 12-h-old foals. Unassigned: Cross-sectional, diagnostic accuracy study. Unassigned: Jugular blood samples were collected from 124 foals at 12 ± 0.5 h after birth. IgG concentrations were estimated using a digital Brix refractometer and measured using the radial immunodiffusion test (RID). Correlation coefficients were calculated between serum Brix percentages...
Recombinant EHV-1 Vector Expressing Immunodominant Hemagglutinin Protein of Equine Influenza Virus H3N8 (Sub-Lineage Florida Clade 2).
Vaccines    July 20, 2026   Volume 14, Issue 7 634 doi: 10.3390/vaccines14070634
Bera BC, Bernela M, Madhwal A, Pradhan SS, Balena V, Anand T, Kandasamy S, Pavulraj S, Ahlawat W, Kandpal D, Mor P, Bishnoi G, Vasdev N, Tripathi BN....Equine herpesvirus type 1 (EHV-1) and equine influenza virus (EIV) are major respiratory pathogens in horses, causing significant economic losses in domesticated horses. Bacterial Artificial Chromosome (BAC) technology can be used to precisely manipulate the EHV-1 genome for the development of live-attenuated vector vaccines. Earlier, our group developed a live-attenuated EHV-1 vaccine by deleting virulence-associated genes using this technology and the mutant EHV-1 has been exploited for expressing foreign gene in the current study. Specifically, in this study, a mutant EHV-1 virus expressing...
Unveiling wolf dietary specialization on free ranging horses using forensic genetics and field monitoring.
Scientific reports    July 20, 2026   doi: 10.1038/s41598-026-59871-3
Freitas J, Godinho R, Mendonça R, Nakamura M, Rio-Maior H, Ringhofer M, Yamamoto S, Hirata S, Álvares F.Wolves occasionally specialize on free-ranging horses when they are abundant and alternative prey is scarce, potentially reducing horse productivity, triggering conflicts with owners, and hampering conservation of both species. Yet, ecological and demographic impacts of wolf predation on horses remain poorly understood. We investigated wolf-horse interactions in NW Portugal by combining wolf monitoring, diet analysis, spatial overlap between wolf and horse activity areas, and horse pedigree reconstruction from genetically identified individuals recovered from wolf scat remains, feeding sites a...
Single-stage orthognathic correction of campylorrhinus lateralis in foals using transection and fixation: Surgical description and outcome of four horses.
Equine veterinary journal    July 18, 2026   doi: 10.1002/evj.70227
Vasco H, Schumacher J, Easley J.Campylorrhinus lateralis ('wry nose') is a rare congenital maxillofacial deformity of foals resulting in compromise of the airway and severe class 4 malocclusion. Various surgical techniques to correct the deformity have been described, but contemporary data on single-stage transection and fixation, including use of a rib graft, and long-term functional and cosmetic outcomes remain underreported. Objective: To describe the transection-and-fixation technique and perioperative management used to correct wry nose in horses, and to report postoperative complications and long-term outcomes of horse...
Preliminary Metabolomic Analysis: Serum Metabolomic Dynamics During Estrus Synchronization in Kazakh Mares.
Animals : an open access journal from MDPI    July 17, 2026   Volume 16, Issue 14 2222 doi: 10.3390/ani16142222
Liu J, Gan J, Yao X, Wang J, Ren W, Meng J, Zeng Y.This study aimed to analyze the differences in serum metabolomes at different stages of estrus synchronization in Kazakh horses, to characterize dynamic changes in serum metabolites during estrus synchronization, and to screen potential metabolic markers and key regulatory pathways. Four sampling stages (M1: intravaginal device insertion; M3: device removal, labeled consistently with the pre-experiment timeline; P: 24 h post-PG injection; L: tertiary follicle emergence) were selected. The research results showed that 37 significantly different metabolites (DAMs) were identified in the M1-vs.-M...
Prevalence of equine lungworm (Dictyocaulus arnfieldi) infection and associated risk factors in Egypt.
Frontiers in veterinary science    July 17, 2026   Volume 13 1895496 doi: 10.3389/fvets.2026.1895496
Gattan HS, Marzok M, Alruhaili MH, Ismail H, Almubarak AI, Selim A. infection is a common parasitic respiratory disease of equines that can adversely affect animal health, welfare, and productivity. However, epidemiological information on this infection remains limited in many regions of Egypt. This study aimed to determine the prevalence of and identify associated risk factors among equines in three Egyptian governorates. Unassigned: A cross-sectional study was conducted on 415 equines, including 150 donkeys, 55 mules, and 210 horses. Animals were examined for , and data on species, age, body condition, and deworming history were collected. Associations bet...
Limited Effects of High-Intensity Laser Therapy on Clinical and Radiographic Outcomes in Three-Year-Old Arabian Racehorses with Dorsal Metacarpal Disease.
Veterinary sciences    July 17, 2026   Volume 13, Issue 7 695 doi: 10.3390/vetsci13070695
Śniegucka K, Soroko-Dubrovina M, Zielińska P, Dudek KD.Dorsal metacarpal disease (DMD) is a common musculoskeletal injury in young racehorses, and effective non-invasive treatments remain of clinical interest. This study aimed to evaluate whether high-intensity laser therapy (HILT), which was applied as the sole intervention in horses retired from training, reduces the clinical signs of DMD compared with untreated controls. During the 2023-2024 racing seasons, 15 Arabian racehorses diagnosed with DMD were enrolled; 9 received HILT and 6 served as controls without laser therapy. The treatment protocol consisted of five daily HILT sessions followed ...
Differential shaping of equine gut microbiota structure and function by breed and feeding regimen.
Frontiers in microbiology    July 16, 2026   Volume 17 1852554 doi: 10.3389/fmicb.2026.1852554
Lin Y, Qiri G, Du M, Dugarjaviin M, Cao J, Fang X, Yun S, Li X, Gong W, Ding W, Bou T, Su S, Chen J, Xing N, Bai D, Zhao Y.The gut microbiota plays an essential role in host energy metabolism and immune function. Horses are non-ruminant herbivores that rely heavily on hindgut microbial fermentation to meet their energy requirements. However, the relative contributions of host genetic background (breed) and environmental factors (feeding regimen and geographical location) to shaping the equine gut microbiota remain poorly understood. Unassigned: In this study, 16S rRNA gene sequencing and functional prediction analysis were performed on 139 equine fecal samples to systematically investigate the differential effects...
Correction to “Vaccine technology helps exported Icelandic horses”.
The Veterinary record    July 16, 2026   Volume 199, Issue 2 86 doi: 10.1002/vetr.71019
No abstract available
Electrochemotherapy Following Surgical Cytoreduction for the Treatment of Recurrent Equine Sarcoids: A Retrospective Study of 23 Lesions.
Veterinary sciences    July 16, 2026   Volume 13, Issue 7 691 doi: 10.3390/vetsci13070691
Spadari A, Meistro F, Tornago R, Facchetti C, D'Angelo P, Ralletti MV, Montemagno S, Rinnovati R.Despite the wide range of therapeutic options currently available for equine sarcoids, recurrence of these lesions remains a major clinical challenge. Consequently, the identification of effective strategies for the management of recurrent sarcoids remains an important objective in equine oncology. The aim of this retrospective study was to evaluate the clinical outcome of surgical cytoreduction combined with intraoperative electrochemotherapy in horses affected by recurrent equine sarcoids. Medical records of horses treated between July 2018 and August 2025 at the Veterinary Teaching Hospital...
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