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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Validation of an improved insect bite hypersensitivity severity score for allergic equine insect bite hypersensitivity in horses.
Journal of veterinary internal medicine    July 7, 2026   Volume 40, Issue 4 aalag132 doi: 10.1093/jvimsj/aalag132
Lam J, Eckert A, Rhiner T, Waldern N, Schwarz E, Birkmann K, Widmer D, Dietrich M, Kündig TM, Fettelschoss-Gabriel A.Insect bite hypersensitivity (IBH) is the most common allergic skin disease in horses, but existing clinical scoring systems lack extensive validation, limiting standardized disease monitoring and therapeutic evaluation. Objective: Develop and validate a standardized, sensitive, and reproducible clinical scoring system for IBH in horses. Methods: Forty-four privately-owned horses with clinically diagnosed IBH examined under field conditions in Switzerland. Methods: In this prospective field validation study, the equine IBH severity score (EqIS) integrates a lesion severity score and an area sc...
Genetic Indicators of Performance Resilience in Barrel Racing Quarter Horses.
Animal genetics    July 7, 2026   Volume 57, Issue 4 e70158 doi: 10.1002/age.70158
Santana ML, Bignardi AB.Resilience, defined as the capacity to maintain consistent performance under variable conditions, has emerged as a relevant breeding objective in livestock systems, yet remains largely unexplored in equine populations. The objectives of this study were to (1) derive indicators of resilience from longitudinal barrel racing time (BRT) records in Brazilian Quarter Horses, (2) estimate genetic parameters for these indicators, and (3) quantify their genetic relationships with BRT and accumulated career earnings (ACE). The dataset comprised BRT records from barrel racing events held between 2010 and...
An Investigation of the Role of Ridden Exercise, Including Application of the Ridden Horse Pain Ethogram, in Pre-Purchase Examinations of Sports Horses.
Animals : an open access journal from MDPI    July 7, 2026   Volume 16, Issue 13 2105 doi: 10.3390/ani16132105
Dyson S.Many horses undergo a pre-purchase examination (PPE) prior to acquisition by a new owner; however, despite evidence that lameness and canter dysfunction may only be apparent during ridden exercise, ridden exercises assessing gait quality is not a routine part of PPEs. The objectives were to determine the influence of the results of ridden exercise on decision-making concerning risk assessment for purchase and to establish the long-term performance of horses. Twenty-five sports horses underwent PPEs including ridden exercises to assess gait quality and to apply the Ridden Horse Pain Ethogram (R...
A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.
Veterinary sciences    July 7, 2026   Volume 13, Issue 7 659 doi: 10.3390/vetsci13070659
Ericsson AC.Molecular microbiology has revolutionized our understanding of the complex host-associated microbiomes required for normative development and physiology. Horses and other members of the family are particularly reliant on the early maturation and lifelong maintenance of an unusually rich hindgut microbiome for optimal digestion and overall health and performance. Research on the equine gut microbiome has accelerated in the past several years, necessitating a renewed appraisal of the field. The present work is a comprehensive and critical review of the literature regarding the bacterial gastroi...
Detection of ionisable lipids in equine plasma by supported liquid extraction and liquid chromatography-high-resolution tandem mass spectrometry for doping control of mRNA agents.
Journal of chromatography. A    July 7, 2026   Volume 1785 467244 doi: 10.1016/j.chroma.2026.467244
Yuen BP, Wong KS, Cheung HW, Ho EN, Wong WT.Messenger ribonucleic acid (mRNA) has emerged as a new class of therapeutic agent with unprecedented potential. In particular, the lipid nanoparticle (LNP)-mRNA formulations enabled safe and effective delivery of mRNA in vivo, leading to the success of mRNA vaccines during the COVID-19 pandemic. To control the potential misuse of LNP-mRNA agents in equine sports, a simple and sensitive method has been developed for the detection of ionisable lipids in equine plasma using supported liquid extraction (SLE) followed by liquid chromatography-high-resolution tandem mass spectrometry. To overcome th...
Factors Influencing Equine Embryo Outcomes in OPU‑ICSI Systems: Insights from a Large‑Scale Program in Brazil.
Journal of equine veterinary science    July 6, 2026   106073 doi: 10.1016/j.jevs.2026.106073
Bordignon V, Buratini J, Cue RI, Barrilari V, Gonçalves MA, Merlini G, Fernandes CB, Squires E, Pontes JHF, Fleury PDC.Equine OPU‑ICSI supports commercial IVEP, yet substantial variability persists. We retrospectively analyzed a large dataset generated in Brazil spanning Quarter Horses, Warmbloods, and Mangalarga to evaluate whether predictors previously identified in the literature show comparable patterns under distinct ecological and breeding conditions. Overall oocyte and embryo outcomes were aligned with broadly reported trends from previous studies. Oocytes retrieved from estrous mares bearing a dominant follicle exhibited higher maturation and blastocyst rates. Stallion effects segregated into distinc...
Prevalence and radiographic features of cyst-like lesions in German Warmblood horses presented for pre-purchase examination.
Frontiers in veterinary science    July 6, 2026   Volume 13 1809383 doi: 10.3389/fvets.2026.1809383
Wendling EM, Hellige M, Freise F, Lingens P, Tietje S, Delling U.Cyst-like lesions (CLLs) are frequently detected during radiographic examinations of equine limbs. They may represent a potential risk factor during pre-purchase examination (PPE) and are of considerable clinical and economic importance, as they may lead to negative purchase decisions. While affected horses may develop lameness, incidental findings have also been reported. The goal of the study was to describe the prevalence, location and radiographic characteristics of CLLs in a group of sound German Warmblood horses. Unassigned: A retrospective cohort study was conducted on 3863 German Warmb...
USE OF GUAIFENESIN-KETAMINE-XYLAZINE INFUSION FOR MAINTENANCE OF ANESTHESIA IN CAPTIVE PREZEWALSKI HORSES (EQUUS FERUS PRZEWALSKI ): A CASE SERIES.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    July 6, 2026   Volume 57, Issue 2 406-411 doi: 10.1638/2025-0122
Hausmann J, Wiedner E, Hinkle S, Johnson JG.This case series documents the use of triple drip, a combination of IV guaifenesin, ketamine, and xylazine (GKX) to extend the length of anesthesia in zoo-owned Przewalski horses (). In three separate procedures involving two different animals, GKX was used to prolong and deepen the plane of anesthesia for 90 to 120 min beyond an initial induction dart containing ketamine, butorphanol, azaperone, and medetomidine. The depth of anesthesia was sufficient to permit surgical excision of SC abscesses and other procedures. Throughout the anesthetic events, the horses breathed spontaneously and maint...
Rapid bacterial community profiling of equine faecal, skin, milk and saliva samples using Oxford Nanopore long-read 16S rRNA amplicon sequencing.
Journal of medical microbiology    July 6, 2026   Volume 75, Issue 7 002176 doi: 10.1099/jmm.0.002176
Leng J, Tait C, Alsubaie B, Van Vliet AHM, Sells P, La Ragione RM, Proudman C. The composition of the equine gut microbiome is associated with many aspects of gastrointestinal, respiratory and musculoskeletal health that have been reported in the horse. Scientific studies exploring the microbiome non-intestinal ecological niches in or on horses are lacking. The clinical use of bacterial community profiling in horses is currently limited by cost and by slow analytical workflows. Most equine microbiome studies have relied on 16S rRNA amplicon sequencing of bacterial DNA, using high-throughput short-read sequencing technologies. This is often provided by an external servic...
Pneumocoele sinus: Computed tomographic findings and surgical approach in a 2-year-old Cob filly.
Equine veterinary journal    July 5, 2026   doi: 10.1002/evj.70226
Thompson SL, Peeters MWJ, Manso-Díaz G, Fiske-Jackson AR.Pneumosinus dilatans and pneumocoele sinus describe abnormal hyperpneumatisation of paranasal sinuses, with the latter being accompanied by thinning of bony walls. Although recognised in human and equine medicine, to the authors' knowledge, this condition's computed tomography (CT) findings and successful surgical approach in horses have not previously been reported in conjunction. Advanced imaging, particularly CT, is pivotal for identifying abnormal sinus expansion and associated nasal obstruction. Methods: Case report. Conclusions: A 2-year-5-month-old Cob filly presented with a 1-month his...
Administration Study of Bedinvetmab, an Antinerve Growth Factor Monoclonal Antibody, in Horses for Doping Control Purposes.
Drug testing and analysis    July 5, 2026   doi: 10.1002/dta.70119
Cheung HW, Wong KS, Choi YC, Kwok WH, So YM, Farrington AF, Ho ENM.Monoclonal antibodies (mAbs) targeting nerve growth factor (NGF) represent a novel therapeutic approach for managing acute and chronic pain in humans and animals. However, their potential misuse as pain-masking agents in competitive equine sports raises significant welfare and integrity concerns. To enhance understanding of the elimination profile of anti-NGF mAb if misused in horses, this study describes the first administration of bedinvetmab (a canine anti-NGF mAb) in three geldings, establishing its plasma elimination profile following subcutaneous administration. Bedinvetmab plasma concen...
Sixty minutes of daily solitary turnout improved physiological and behavioral indicators of stress and welfare in stall-housed horses.
Journal of equine veterinary science    July 4, 2026   106075 doi: 10.1016/j.jevs.2026.106075
Rodgers EE, Yates DT, Parrish BL, Luck LM.Housing horses in stalls restricts natural roaming behaviors, which in turn increases stress and stereotypic behaviors. Daily turnout for voluntary exercise is common for stress mitigation, but there is no consensus for optimal duration of turnout sessions. Objective: We sought to understand how minimal and moderate-duration daily turnout affects behavioral and physiological stress indicators. Methods: In a Latin-square design, adult Quarter horses (N=11) were allowed 0, 15, or 60 minutes/day of solitary turnout for 12-day periods. In-stall behaviors and 24-hour time budgets were assessed on d...
Vaccine technology helps exported Icelandic horses.
The Veterinary record    July 3, 2026   Volume 199, Issue 1 37-38 doi: 10.1002/vetr.70944
Paillot R, Waller AS, Björnsdóttir SH, Denmeade C.No abstract available
Do preoperative antimicrobials reduce surgical site infections in horses undergoing arthroscopy?
The Veterinary record    July 3, 2026   Volume 199, Issue 1 33 doi: 10.1002/vetr.70938
Roberts H, Brennan M.No abstract available
Effects of Nebulized Alpha-2 Macroglobulin in Horses with Lower Airway Inflammation.
Journal of equine veterinary science    July 3, 2026   106076 doi: 10.1016/j.jevs.2026.106076
Pfeifle RL, Hart KA, Berghaus LJ, Coleman MC.Equine asthma is a chronic inflammatory airway disease with limited safe long-term treatments. Alpha-2-macroglobulin (A2M), a natural anti-inflammatory protease inhibitor, may provide a novel non-steroidal therapeutic option for horses with lower respiratory tract inflammation. Objective: To characterize the impact of nebulization with alpha-2-macroglobulin (A2M) on clinical signs, bronchoalveolar lavage cytology, and local and systemic cytokine response in horses with lower respiratory tract inflammation. Methods: Thirteen university-owned horses with lower airway inflammation were randomized...
Mammary neuroendocrine tumor in a mare. Jordan R, Roa F, Santonastaso A, Uzal FA, Stevenson V.A 10-y-old American Paint Horse mare was presented to the Equine Field Services at Virginia-Maryland College of Veterinary Medicine (Blacksburg, VA, USA) for evaluation of mastitis and a possible abscess in the right mamma. Histologic evaluation of a mammary biopsy revealed a densely cellular, infiltrative neoplasm with cells arranged in packets supported by thin stroma. In a neuroendocrine immunohistochemistry panel, the neoplastic cells did not immunolabel for neuron-specific enolase or synaptophysin, positively immunolabeled for chromogranin A, and had moderate scattered immunolabeling for ...
Repeatability and test-retest reliability of thermal and pressure pain threshold testing in healthy thoroughbred horses.
Frontiers in veterinary science    July 3, 2026   Volume 13 1887508 doi: 10.3389/fvets.2026.1887508
Khatib JL, De Gennaro C, Masters TM, Messer SL, Moura RA, Mallicote MF, Chiavaccini L.Quantitative sensory testing (QST) has been used in horses to assess nociceptive responsiveness but its broader clinical application is limited by variability across anatomical sites, environmental conditions, operator technique, and behavioral endpoints. This study aimed to evaluate the feasibility, within-session repeatability, and test-retest reliability of thermal threshold (TT) and pressure pain threshold (PPT) testing in healthy Thoroughbred horses. Unassigned: Eleven adult Thoroughbred horses (4 mares, 7 geldings; median [IQR] age 6 [5-6] years; body weight 558 ± 47 kg) underwent...
Effects of flow-controlled expiration on oxygenation and early recovery in horses undergoing general anaesthesia.
Equine veterinary journal    July 2, 2026   doi: 10.1002/evj.70217
Mika A, Brandly J, Frampton A, Douglas H, Starr M, Benchimol H, Hopster K.FLow-controlled EXpiration (FLEX) has been shown to significantly enhance oxygenation in horses under clinical and experimental conditions. Objective: To compare pulmonary gas exchange during early recovery following general anaesthesia in horses ventilated with FLEX compared with conventional intermittent positive pressure ventilation (IPPV) and to assess recovery characteristics between ventilation modes. Methods: Randomised, crossover in vivo experiments. Methods: Six adult horses underwent two 2-h anaesthetic episodes in a randomised crossover design (FLEX vs. IPPV), separated by a two-wee...
Spatiotemporal dynamics of equine group formation reveal the gradual emergence of social cohesion.
Scientific reports    July 2, 2026   doi: 10.1038/s41598-026-59260-w
Torres Borda L, Auer U, Kelemen Z, Cockburn M, Jenner F.Stable social relationships are essential for horse welfare, yet domestic management often involves regrouping unfamiliar individuals, potentially causing social stress. Fine-scale dynamics of social integration remain poorly quantified due to limitations of observational sampling. Using ultra-wideband real-time positioning, we tracked the development of spatial and social relationships in two newly formed equine groups (n = 19) over 2-12 months. Inter-individual distances decreased significantly, with time spent within 3 m of conspecifics increasing from 1.2 to 27.3% within two months, d...
Correction: Phenylbutazone concentrations in synovial fluid following administration via intravenous regional limb perfusion in the forelimbs of six adult horses.
Frontiers in veterinary science    July 1, 2026   Volume 13 1869864 doi: 10.3389/fvets.2026.1869864
O'Brien M, Mochel JP, Kersh K, Wang C, Troy J.[This corrects the article DOI: 10.3389/fmed.2026.1810077.].
Using a wearable electrocardiogram (ECG) patch adapted for 7-day monitoring in the horse.
Equine veterinary journal    July 1, 2026   doi: 10.1002/evj.70223
Delecave Dias T, Hauser RG, Cleary KB, Durward-Akhurst S.Arrhythmias can cause poor performance and sudden death in horses. Long-term (>24 h) electrocardiogram (ECG) monitoring has been used to identify arrhythmias in humans and is superior to short-term monitoring for transient arrhythmia detection. Televet is the current equine gold-standard ECG device. The Cardea SOLO™ (CS) is a single-use monitor with automated ECG analysis software allowing ECG monitoring for 7 days. Objective: Our objective was to validate the performance of the CS compared to the Televet. Methods: Method validation. Methods: ECGs were performed on 12 healthy horses s...
Orchiectomy in horses: closed technique and primary closure of the incision.
Journal of the American Veterinary Medical Association    July 1, 2026   1 doi: 10.2460/javma.26.02.0091
Prazeres J, Borges J, Teixeira D, Agrícola R, Carvalho L, Ribeiro G.To provide a video tutorial on how to perform equine castrations using the closed technique and primary closure of the skin. Unassigned: Intact male horses presented to equine veterinary hospitals for castration. Unassigned: The closed castration technique was performed with incisions over the inguinal rings and primary closure. Unassigned: This technique is associated with minimal complications, decreased edema, less pain, lower infection rates, and faster healing. Unassigned: The technique presented in this video tutorial provides a quick and safe method for removing descended as well as non...
Vietnam’s Horse Sector: A Comprehensive Review of History, Production Systems, Health Challenges, and Research Priorities.
Animals : an open access journal from MDPI    July 1, 2026   Volume 16, Issue 13 2015 doi: 10.3390/ani16132015
Nguyen VT, Ba NV, Van Dai N, Pham LD, Do DN.Horses in Vietnam have a long historical presence and continue to hold economic, socio-cultural, and medicinal importance across diverse regions. Despite these roles, comprehensive scientific information on equine development, including health and disease patterns, reproductive performance, genetic resources, and biomedical applications, remains limited and fragmented. In this review, we summarize existing knowledge on equine populations, production systems, and their development in Vietnam, as well as their roles in cultural practices, livelihoods, and traditional medicine. We then identify m...
A point-based laminitis risk scoring system and machine learning framework for prediction of laminitis in horses.
Frontiers in veterinary science    July 1, 2026   Volume 13 1809041 doi: 10.3389/fvets.2026.1809041
Abdullah , Bensmail H, Johnson JP, Bouhali O.Laminitis is a painful and potentially life-threatening inflammatory condition of the equine hoof, and its detection remains a major challenge in veterinary practice. Although several risk factors have been reported, the prediction of the onset of laminitis in a subclinical stage using routine clinical data is still limited. This study aims to address this gap by developing an interpretable machine learning (ML) framework for the prediction of the risk of laminitis in horses. A point-based risk scoring system was first constructed using multivariate logistic regression to quantify the contribu...
Straight sesamoidean ligament desmopathy commonly occurs with proximal interphalangeal joint osteoarthritis.
Equine veterinary journal    July 1, 2026   doi: 10.1002/evj.70214
Barton CK, Samol MA, Selberg KT, Goodrich LR.Proximal interphalangeal joint osteoarthritis (PIPJ OA) is a common cause of poor performance in the equine athlete; however, the supporting soft tissue structures surrounding the joint are seldom evaluated. Straight sesamoidean ligament injuries have been previously hypothesised to be concomitant with PIPJ OA; however, the frequency of these lesions coinciding with PIPJ OA has not been fully investigated. Objective: To investigate the prevalence of straight sesamoidean ligament desmopathy (SSLD) in horses presenting with PIPJ OA. Methods: Retrospective clinical study. Methods: Horses presenti...
Improving Inclusivity in the Curriculum via the Introduction of an Equine Industry-Specific Language eGlossary.
Journal of veterinary medical education    July 1, 2026   e20250128 doi: 10.3138/jvme-2025-0128
Maile C, Cave K, Hutchings C, Prutton A.The equine veterinary profession is frequently considered inaccessible to veterinary students who have had limited exposure to the equine industry. One of the perceived reasons for this inaccessibility is the use of what is often coined "horsey" language within the industry. If a student has limited experience of the equine industry, there is a potential language barrier to teaching, which may result in poor engagement with equine teaching and placements. The aim of this Teaching Tip is to describe the development and evaluation of a new teaching resource designed to demystify equine industry-...
Comparative clinical and thermographic responses to dexamethasone and saline solution mesotherapy in horses with spinal disorders.
Frontiers in veterinary science    June 30, 2026   Volume 13 1839834 doi: 10.3389/fvets.2026.1839834
Jacobsen TK, Azevedo MDS, Colla S, Carvalho AR, De La Corte FD, De Bastiani G.Back pain and spinal dysfunction in horses are multifactorial conditions frequently associated with musculoskeletal alterations that may impair mobility, performance, and welfare. Mesotherapy has emerged as a minimally invasive adjunctive approach for managing musculoskeletal disorders; however, comparative clinical responses to different intradermal protocols in equine spinal conditions remain insufficiently investigated. The present study aims to compare the clinical and thermographic responses of two mesotherapy protocols in horses diagnosed with cervical or thoracolumbar spinal disorders. ...
Inertial measurement units are comparable to motion capture for measuring intersegmental spinal angular velocities in horses.
American journal of veterinary research    June 29, 2026   1-7 doi: 10.2460/ajvr.26.04.0149
Ursini T, Clayton H, Levine D, Richards J.To compare inertial measurement unit (IMU)-derived intersegmental spinal motion data with measurements obtained from a marker-based motion-capture system. Unassigned: 4 horses were instrumented with custom marker clusters incorporating a 3-D-printed base designed to secure the IMU, ensuring both systems recorded data from the same anatomical location and orientation. A total of 3,737 paired time points across 37 gait cycles were analyzed. Agreement in intersegmental angular velocities across 3 planes of motion was evaluated using Bland-Altman analysis and intraclass correlation coefficients. U...
Diagnostic criteria for equine thoracolumbar myofascial pain syndrome: A foundational study.
Research in veterinary science    June 27, 2026   Volume 210 106314 doi: 10.1016/j.rvsc.2026.106314
Resano-Zuazu M, Carmona JU, Fernández-de-Las-Peñas C, Argüelles D.Diagnostic criteria for myofascial pain syndrome (MPS) are well established in humans but remain underexplored in horses. This study aimed to identify which MPS clinical signs were present in the equine thoracolumbar region, assess internal coherence among clinical indicators, and explore the diagnostic relevance of owner-reported behavioural, signalment, management, and clinical variables. A population of 120 horses underwent a static physical assessment of the thoracolumbar region. Owner-reported horse behaviours were collected through a questionnaire. Taut band, hypersensitive spot, local t...
Jejunocecostomy in horses-a review of its unique complexities.
Veterinary surgery : VS    June 26, 2026   doi: 10.1111/vsu.70129
Freeman DE, Bauck AG, Chanutin S, Moyer EK, Smith B.Jejunocecostomy (JC), or jejunocecal anastomosis, is arguably the most controversial surgical procedure in equine small intestinal surgery. It is also the only option for resection and anastomosis for a third of small intestinal strangulating lesions in horses. Critics of the procedure identify its low survival and high complication rates as reasons to avoid its use. This review is intended to highlight findings of recent research and clinical studies that validate use of the JC, and to provide some insights into technical aspects of the procedure that might improve its survival rates. Jejunoc...