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Topic:Veterinary Medicine
Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Towards a Comprehensive Screening Approach for Detecting Gene Doping in Racehorses and Sport Horses by Targeting Common and Intrinsic Plasmid Sequences. The evolution of biotechnology and gene therapy has unfortunately facilitated the emergence of gene doping. Those misused applications are prohibited in equestrian sports (International Equestrian Federation (FEI)) and in horseracing (International Federation of Horseracing Authorities [IFHA]), reflecting major concerns regarding horse welfare and the integrity of competitions. Among the biotechnological tools that could be misused, eukaryotic expression plasmids represent a particular threat due to their ease of production, customisable design and ability to carry a wide range of performance ...
Current consensus and controversies in equine parasite control. Julia Shrubb, chair of CANTER - Controlling ANTiparasitic resistance in Equines Responsibly - takes a look at where there is currently agreement on equine parasite control practices and where debate is ongoing.
Bacteroides fragilis – an overlooked cause of abortion in the mare? A near late-term pregnant mare developed purulent vaginal discharge, fever and peripheral edema. Preterm foaling was medically induced, and the mare delivered a weak foal that was subsequently euthanized. Necropsy revealed an extensive, severe allantochoroiditis affecting the entire corpus segment. Necrosuppurative choroiditis with multiple colonies of gram-negative bacilli and suppurative bronchioalveolitis was found at histology. Anaerobic culture of the chorion revealed a mixed culture clearly dominated by Bacteroides fragilis. B. fragilis has not previously been associated with abortion in...
Cracks in the ice: biological challenges and incremental progress in equine oocyte vitrification. Equine oocyte vitrification could enhance the flexibility of in vitro embryo production, yet developmental competence remains reduced. Only vitrification of oocytes matured in vivo yields foaling rates comparable to fresh oocytes. Recent advances in vitrification at the germinal vesicle (GV) stage, supported by systematic comparisons of cryoprotective agents and exposure times, has enabled consistent blastocyst production and birth of several foals. Comparative studies of GV and metaphase II (MII) stages suggest biological advantages of vitrification after in vitro maturation (IVM), warranting...
Epidemiological evidence of anti-Leptospira antibodies in horses at a global level (years 2015 to 2025): a systematic review and meta-analysis. Leptospirosis is a bacterial zoonotic disease with clinical consequences and potential sequelae in horses. Objective: To estimate the pooled global seroprevalence of anti-Leptospira antibodies in horses, detected with the Microscopic Agglutination Test, the frequency by serogroups and serovars, the geographical distribution of studies and the main reported clinical signs and organic manifestations through a systematic review and meta-analysis. Methods: A bibliographic search was conducted for cross-sectional epidemiologic studies published between 2015 and 2025. The risk of bias was determined...
Continuous Bluetooth pulse oximetry monitoring in conscious and anesthetized horses: a pilot study. To assess the feasibility, patient tolerance, and accuracy of a wireless Bluetooth pulse oximeter sensor system on horses for an extended period. Unassigned: A prospective, case-control, unblinded study involved 7 horses at risk of hypoxemia and 7 healthy controls. A wireless Bluetooth transmission sensor was attached to their nostril for a prolonged period. Sensor retention time, patient tolerance, and sensor performance in capturing valid monitoring points were recorded. During the monitoring, 4 samples of arterial blood were collected, and paired measurements (SaO2) and estimations (SpO2) o...
Pharmaceutical and Nutraceutical Therapies for Liver Disease. Liver dysfunction may reduce the metabolism of drugs that undergo extensive hepatic processing. This will lead to reduced clearance and elimination, and can cause accumulation of the drug, increasing the risk of toxicity. Pentoxifylline and ursodeoxycholic acid are 2 pharmaceuticals that can provide benefits for a variety of equine hepatic diseases. Nutraceuticals are frequently used in horses with hepatopathy, targeting oxidative stress, inflammation, and hepatocellular injury. Neutraceuticals such as S-adenosylmethionine, silymarin and vitamin E are most commonly used although extensive rese...
Impact of ununited plantar eminence of the first phalanx on early racing performance in North American Standardbreds. To determine the prevalence of ununited plantar eminence (UPE) of the first phalanx (P1) in North American Standardbreds and evaluate its association with early racing performance. Methods: Retrospective cohort study with matched sibling controls. Methods: Imaging records from 1897 yearling Standardbred horses. Methods: Screening images were reviewed for the presence of UPE and other orthopedic abnormalities. Sex, age, sire, gait, and racing performance data were obtained from the United States Trotting Association. Affected horses were compared with unaffected siblings using non-parametric te...
Single-dose intravenous α2-agonists do not acutely alter anti-inflammatory bioactive protein profiles but reduce interleukin-8 in equine autologous protein solution and platelet-rich plasma. Determine the acute effects of xylazine and detomidine on concentrations of selected growth factors, cytokines, and α2-macroglobulin (A2M) in platelet-rich plasma (PRP) and autologous protein solution (APS) and the long-term effects of these sedatives on serum A2M. We hypothesized that sedative administration would decrease concentrations of all bioactive proteins in PRP and APS acutely and A2M in serum for 6 days following sedative administration. Unassigned: 6 horses were randomized to receive IV xylazine (200 mg) or detomidine (10 mg). Blood was collected before and 5 minutes after sedativ...
Evaluation of Point-of-Care Coagulation Measurement Systems for Activated Clotting Time and Partial Thromboplastin Time in Heparinized and Non-Heparinized Equine Blood. To compare the performance of one point-of-care activated clotting time (ACT) machine (Vet-Tube), one point-of-care activated partial thromboplastin time (aPTT) machine (Coagulation DX), and one bench-top ACT machine (Medtronic ACT II plus) with previously published measurements from stationary devices in whole blood from healthy horses. Methods: Prospective, observational study SETTING: University veterinary teaching hospital, from August 2023 to September 2023. Methods: Thirty healthy university-owned horses. Methods: ACT and aPTT were measured via point-of-care analyzers (ACT POC, aPTT POC)...
Seroprevalence of Leptospira in Lavradeiro horses, a semi-feral ecotype from the Northern Brazilian Amazon. Leptospirosis is a neglected zoonosis with significant impact on public and veterinary health, with equines acting as potential maintenance hosts of infection. This study aimed to investigate the seroprevalence of Leptospira in Lavradeiro horses under semi-feral conditions in Indigenous communities in the state of Roraima, Brazil. A total of 387 serum samples were subjected to the microscopic agglutination test (MAT), using antigens of Leptospira spp. from 18 serogroups. The overall prevalence was 15.8% (95% CI: 12.3-19.8%), with the most frequent serogroups being Australis, Tarassovi, Autumna...
Imaging of the Equine Abdomen Using Point of Care Ultrasound (POCUS)-A Resource for the Equine Practitioner. Wireless ultrasound (US) probes for point of care (POC) evaluation of horses presented for veterinary evaluation of colic have become widely available in recent years. The availability and performance of this technology mean POCUS is readily available to the equine practitioner and the technology is well suited to patient evaluation or serial monitoring in first opinion practice. In human health care and veterinary contexts, it has been suggested that there is a need for practitioners to better appreciate the value of POCUS for assessment of gastrointestinal structure and function. This study ...
Radiographic identification and description of the equine middle conchal sinus (ethmoidal sinus): Implications for diagnosing middle conchal sinusitis. The middle conchal sinus (MCS) (ethmoidal sinus) remains one of the least understood equine paranasal compartments. Despite recognition of its involvement in sinonasal disease, disorders of the MCS often remain underdiagnosed in the absence of computed tomographic (CT) imaging due to limited anatomical understanding and challenges with radiographic visualisation. Objective: The objectives of the study were (1) to characterise the radiographic features and anatomical location of the MCS in horses and (2) to illustrate the practical relevance of the anatomical and radiographic findings in two cl...
Novel technique for correcting urovagina via urethral transposition in the horse. Vesicovaginal reflux is a common cause of infertility in mares. Surgical correction is commonly recommended and involves caudal relocation of the urethral orifice which forces the urine to be expelled caudally. There have been several previously described techniques. Complications associated with caudal urethral extension occur in 11-33.3% of cases. Objective: To identify a novel technique for performing caudal urethral translocation that effectively corrects vesicovaginal reflux with minimal associated complications. Methods: In vivo experiment and clinical case series. Methods: The experimen...
Comparison of Magnetic Resonance Imaging and Computed Tomography for Evaluation of Cervical Vertebral Nerves and Synovial Tissues in Horses with Cervical Spinal Disease. Pathology of the cervical spine is an important cause of poor performance in sport horses. Computed tomography (CT) and magnetic resonance imaging (MRI) have improved musculoskeletal diagnostic capabilities. CT is well-suited to assess osseous pathology, although it is limited for assessing soft tissues. MRI, the gold standard for imaging soft tissues, cannot be used for antemortem imaging of the equine cervical spine. The diagnostic potential of CT for evaluating soft tissues of the equine cervical spine compared to MRI is not well-defined and warrants investigation. Postmortem MRI was perfor...
Morbidity associated with inhalation anesthesia in horses: the role of opioid use in a university teaching hospital. Despite concerns among equine practitioners, the effects of opioid administration on intraoperative complications during inhalation anesthesia remain incompletely characterized. This retrospective study evaluated intraoperative complications and perianesthetic mortality in horses undergoing inhalation anesthesia according to opioid use. Medical records from a university veterinary hospital were reviewed (2014-2025) and grouped based on opioid inclusion in anesthetic protocols and surgery type (colic vs. non-colic). Intraoperative hypotension (MAP < 70 mmHg), hypothermia (temperature 65 mmH...
Cervical spinal cord compression may affect anesthetic recovery quality and seizure incidence in horses after myelography. To compare anesthetic recovery quality and seizure incidence after cervical myelography in horses with or without cervical spinal cord compression. Unassigned: Anesthesia and medical records from January 2017 to December 2022 of horses anesthetized for myelography were retrieved. Patients with incomplete records, equine protozoal myeloencephalitis diagnosis, or an anesthetic protocol outside an established standard were excluded. Demographic analysis, ataxia score, and anesthetic management variables were recorded in an observational retrospective fashion. Each variable was compared between gr...
Reduced centrifugation duration improves diagnostic performance of an equine tapeworm egg counting technique. Anoplocephala perfoliata, can cause severe health problems in horses. Standard coprological tests have performed poorly for detecting A. perfoliata, and while a centrifugation-enhanced flotation technique is superior to other techniques, it is time consuming due to three 10-minute centrifugation steps. This study aimed to evaluate modifications of this technique that reduce the centrifugation durations to 5 and 1 min, respectively. Fecal samples were collected from ten adult A. perfoliata egg count positive mares and divided into 9 subsamples to allow for three replicate counts for each of th...
Evidence of Physiological Comodulation During Human-Animal Interaction: A Systematic Review. This review examines the evidence in the literature for physiological co-modulation during human-animal interaction, identifying studies that assessed comodulation via simultaneous measurement of physiological signals in both species, performing quantitative comparisons. We searched (last search: August 5, 2025) PubMed, EMBASE, Scopus, Google Scholar, Animal Studies Repository, Cochrane, and the Consensus App academic search engine. Risk of bias was assessed using an adapted version of the ROBINS-I V2 tool. The results, grouped by data analysis method, interaction context, and physiological pa...
OPTIMIZING EXTRACTION AND CONCENTRATION METHODS FOR LC-MS/MS ANALYSIS OF VETERINARY PHARMACEUTICALS IN EQUINE-ASSOCIATED ENVIRONMENTAL MATRICES. This study developed a method for the simultaneous quantification of six potentially environmentally toxic veterinary drugs: benzylpenicillin, acepromazine, flunixin, dexamethasone, ketamine and romifidine, in soils, sediments, equine faeces and natural waters. Three methods were compared for their extraction from solid matrices: Ultrasonic extraction (USE), QuEChERS and Accelerated Solvent Extraction (ASE). ASE method was optimized according to temperature and extraction cycles. Quantification was performed by LC-MS/MS. LC and MS parameters were optimized. The method was validated according t...
Comparative metagenomic analysis of gut microbiomes in Yunnan ponies and Dutch warmblood horses. The Yunnan pony is an officially protected pony breed in China. However, its gut microbiome characteristics remain largely unexplored. This study aimed to compare the gut microbiome and antibiotic resistance genes (ARGs) profiles between Yunnan ponies and Dutch warmblood horses. Unassigned: A total of 14 fresh fecal samples were collected from Yunnan ponies and Dutch warmblood horses. Metagenomic sequencing was employed to comprehensively analyze and compare the gut microbial composition, function, and ARGs profiles between the two breeds. Unassigned: The results showed no significant differen...
Physiological determinants of plasma biochemical parameters in horses: a structured review. The biochemical profile of horses is a cornerstone in equine clinical diagnostics, offering valuable insights into health status, disease progression, and physiological adaptation to internal and external stimuli. However, the interpretation of these biochemical parameters is far from straightforward, as they are subject to significant variation influenced by a range of physiological factors. Age, sex, breed, level of physical activity, nutritional condition, and reproductive status can all modulate baseline biochemical values, potentially leading to diagnostic inaccuracies if not properly con...
Genomic diversity of multidrug-resistant Rhodococcus equi: novel sequence types, pangenome architecture, and phylogenomic evolution. Rhodococcus equi is a major cause of life-threatening pneumonia in foals under 6 months of age and an opportunistic pathogen in immunocompromised humans. Although common in soil and equine farm environments, its evolutionary dynamics, virulence architecture, and pathways of antimicrobial resistance (AMR) emergence remain poorly understood. This study integrated phenotypic characterization and whole-genome sequencing of 46 R. equi isolates from horses submitted for necropsy (n = 45) and equine fecal samples (n = 1) in Kentucky between January 2022 and December 2023 to define their resistance la...
First molecular detection of Theileria haneyi infection in horses in Southern Spain. Equine piroplasmosis (EP) is a tick-borne disease of equids caused by the hemoparasites , and . , a close relative of that causes mild clinical signs under experimental conditions, has been reported in several countries, adding complexity to EP ecology, diagnosis, and treatment. However, its presence in Spain remains unknown, which is concerning given the country's importance in equine genetics and international trade. Hereby, we investigated the presence of in blood samples from equids in Spain. Unassigned: Blood samples from 222 equids (218 horses, two donkeys, two mules) suspected of EP a...
Plasma and urinary exposure of cannabidiol and cannabidiolic acid in horses following consumption of contaminated feed. Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive cannabinoids naturally present in hemp-derived products. While these compounds are prohibited during equine competition, horses may be inadvertently exposed through contaminated feed. Data describing systemic and urinary exposure to CBD and CBDA following such low-dose, involuntary intake are limited. This study aimed to describe plasma and urine concentration-time profiles of CBD and CBDA in horses after consumption of experimentally contaminated feed. Results: Twelve Standardbred horses received feed containing low doses (1...
Application of Anti-Müllerian Hormone in Regulation of Ovarian Function and Its Practical Relevance for Fertility and Embryo Production in Cows and Mares. In the female organism, Anti-Müllerian hormone (AMH) is produced exclusively by granulosa cells, particularly in secondary and early tertiary follicles. The amount of AMH released into the blood is proportional to the total number of follicles present in the ovaries and is therefore used to estimate the ovarian functional reserve. In both cattle and mares, a strong and highly repeatable association has also been demonstrated between AMH concentrations and antral follicle count. Therefore, AMH may serve as a biomarker with broad diagnostic utility in reproductive medicine in these species, as ...
Prevalence, risk factors, and antimicrobial resistance of Staphylococcus aureus in equines in Egypt. Staphylococcus aureus is a common commensal organism in both humans and animals, frequently colonizing the skin and nasal cavities of healthy individuals, although it can also cause a wide range of severe infections. The present study investigated the prevalence and risk factors of S. aureus in equines, along with antimicrobial resistance patterns of methicillin-resistant S. aureus (MRSA) isolates. The results revealed a prevalence of 38.6% in nasal samples collected from equines, highlighting the organism's significant presence and potential to cause infections in these animals. A genotypic p...
Viral Hepatitis. Since 2012, 2 viral causes of hepatitis have been identified in horses. Much remains to be discovered about their transmission, risk factors for clinical disease, diagnosis, and treatment approaches. Equine parvovirus-hepatitis has been identified as the cause of acute hepatic necrosis, previously known as Theiler's disease. Equine hepacivirus is recognized as a cause of chronic fibrosing hepatitis. Diagnosis relies on ruling out other causes of hepatitis and documenting infection by serum or liver polymerase chain reaction. There is no direct antiviral for either condition and treatments are ...
The Early Ophthalmic Effects of Vatinoxan in Healthy Detomidine-Sedated Horses. To evaluate the short-term ophthalmic effects of vatinoxan, a peripherally selective alpha2-adrenoceptor antagonist, in detomidine-sedated horses. Methods: Seven healthy horses without ophthalmic disease in a randomized, masked, two-period crossover study design, with a ≥ 7-day rest period. Methods: After a bilateral palpebral block (lidocaine 40 mg) and baseline data collection, horses received intravenous detomidine (20 μg/kg [DET]) or DET with vatinoxan (200 μg/kg [DET-VAT]). Intraocular pressure (IOP) was measured from the left eye while tear production (Schirmer tear test -1; ...
West Nile Virus in Horses as a Sentinel Host in One Health Surveillance: Epidemiological Insights and Future Perspectives. West Nile virus (WNV) is a globally distributed mosquito-borne flavivirus with significant implications for both veterinary and public health. While horses are incidental dead-end hosts, their epidemiological role extends beyond clinical disease, as they can serve as effective sentinel hosts for detecting local viral circulation. Their frequent exposure to mosquito vectors, ability to mount measurable antibody responses, geographic stability, accessibility for monitoring, and the possibility of observation within managed owner-veterinarian systems make them particularly suitable for surveillan...
