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Rare alleles, MHC and captive breeding.
EXS    January 1, 1994   Volume 68 187-204 doi: 10.1007/978-3-0348-8510-2_16
Hedrick PW, Miller PS.In recent years, more detailed genetic information has become available for individuals of endangered species in captive breeding programs. There have been suggestions that this information be used to identify rare alleles, particularly those at the MHC, that can be subsequently selected for captive breeding programs. First, we summarize the current information on the MHC relevant to conservation genetics, so that such a possible breeding program is seen in a proper perspective. For example, very few specific alleles at the MHC have been identified as selectively advantageous, even though ther...
Fibre type distribution, capillarization and enzymatic profile of locomotor and nonlocomotor muscles of horses and steers.
Acta anatomica    January 1, 1994   Volume 151, Issue 2 97-106 doi: 10.1159/000147649
Karlström K, Essén-Gustavsson B, Lindholm A.Samples were taken at slaughter from heart and both locomotor and nonlocomotor muscles from animals of similar body weight but adapted to different levels of activity: three horses and three steers. All samples were analyzed biochemically to measure the activity of key metabolic enzymes. The skeletal muscles were analyzed histochemically for fibre type composition, fibre area and capillary supply. The general pattern of differences in fibre type composition and metabolic profile between muscle groups was similar in both horses and steers. The hearts of both species had high citrate synthase (C...
Culture of equine embryos in media containing egg yolk, mare’s milk and saline: Preliminary results.
Theriogenology    January 1, 1994   Volume 41, Issue 6 1201-1206 doi: 10.1016/0093-691x(94)90476-y
Lebedev SG, Lebedeva LF.A medium containing egg yolk, mare's milk and/or modified PBS was used to culture Day-8 to 8.5 equine blastocysts. Twenty-one variants of the medium containing different concentrations of the 3 components were prepared. Embryos were recovered nonsurgically and placed into the media at 37 degrees C for 24 h. A total of 45 embryos was cultured; of these 7 died in culture and 13 showed inadequate development at the onset, while 25 continued to grow in the media. It was established that embryos grew best in media containing 20 to 60% yolk, 20 to 60% mare's milk and/or 20 to 60% PBS. It was found e...
Epidemiology of equine motor neuron disease.
Veterinary research    January 1, 1994   Volume 25, Issue 2-3 275-278 
Mohammed HO, Cummings JF, Divers TJ, de la Rua-Domenech R, de Lahunter A.Equine motor neuron disease (EMND) is a newly recognized neurodegenerative disorder of bulbospinal motor neurons in the horse. We conducted a case-control study to identify intrinsic factors associated with the risk of this disorder. Seventy-four cases and 160 controls were assembled. Controls included horses diagnosed with equine protozoal myelitis, equine degenerative myeloencephalopathy, and cervical stenotic myelopathy during the same time period as the cases. Logistic regression analysis was used to evaluate the association of each hypothesized factor while simultaneously controlling for ...
Heparin: a review of its pharmacology and therapeutic use in horses.
Journal of veterinary internal medicine    January 1, 1994   Volume 8, Issue 1 26-35 doi: 10.1111/j.1939-1676.1994.tb03192.x
Moore BR, Hinchcliff KW.Heparin is used clinically in horses to treat hemostatic abnormalities associated with severe gastrointestinal disease, septicemia, and endotoxemia. The primary anticoagulant effect of heparin is through the suppression of thrombin-dependent amplification of the coagulation cascade, and inhibition of thrombin-mediated conversion of fibrinogen to fibrin. Heparin may be of benefit in preventing the complications associated with hypercoagulable states such as jugular vein thrombosis, laminitis, and organ failure. Heparin may also be beneficial in the prevention of intraabdominal adhesions after g...
Diagnosis of eastern equine encephalomyelitis virus infection in horses by immunoglobulin M and G capture enzyme-linked immunosorbent assay. Sahu SP, Alstad AD, Pedersen DD, Pearson JE.Immunoglobulin M (IgM) and G (IgG) capture enzyme-linked immunosorbent assays (ELISAs) were used as possible adjuncts to hemagglutination inhibition (HI) and virus neutralization (VN) tests to differentiate between reaction to recent exposure to eastern equine encephalomyelitis (EEE) virus and those due to prior vaccination. Serum samples were evaluated by the IgM-capture ELISA, and the results were compared with those of HI and VN tests. Of 381 serum samples, 51% (195 samples) were positive by HI test (> or = 1:40) and 54% (205 samples) were positive by VN test (> or = 1:10), but only 3...
Equine fetal kinetics: entry and retention of fetal hind limbs in a uterine horn.
Theriogenology    January 1, 1994   Volume 41, Issue 4 795-807 doi: 10.1016/0093-691x(94)90496-6
Ginther OJ, Williams D, Curran S.Transrectal ultrasonic examinations were made in 31 pregnant pony mares once a week during Months 6 to 11. Each uterine horn was divided into 3 approximately equal segments (caudal, middle, cranial). The percentage of examinations with cranial fetal presentation increased (P<0.05) progressively from 58% at Month 6 to 99% at Month 9 and was followed in all mares by entry of the fetal hind limbs into one uterine horn. The mean number of uterinehorn segments with limb parts increased (P<0.05) between each set of consecutive months from Month 6 to Month 10. Initially (Months 7 and 8), retrac...
Frequency and morpho-structural organization of the thyroid gland isthmus in horses, donkeys and small ruminants.
Bollettino della Societa italiana di biologia sperimentale    January 1, 1994   Volume 70, Issue 1-2 1-4 
Zedda M, Acone F, Bo Minelli L, Sanna L.No abstract available
Proteolytic enzymes in equine joints with infectious arthritis.
Equine veterinary journal    January 1, 1994   Volume 26, Issue 1 48-50 doi: 10.1111/j.2042-3306.1994.tb04330.x
Spiers S, May SA, Harrison LJ, Bennett D, Edwards GB.Significant amounts of collagenase and caseinase activity were detected in infected synovial fluid samples. Partial characterisation of the enzymes by gel filtration suggested that synovial fluid from cases of infectious arthritis may contain enzymes from both the synovial cells and neutrophils. This finding was also supported by analysis of sequential synovial fluid samples from 4 infected joints. In 3 joints the concentration of caseinase and in 1 joint collagenase paralleled the decline in total nucleated cell count. However, in 3 joints the concentration of collagenase remained high after ...
[The genital microflora in the stallion–microbiological study of presecretion samples from 1972 to 1991].
DTW. Deutsche tierarztliche Wochenschrift    January 1, 1994   Volume 101, Issue 1 18-22 
Scherbarth R, Pózvári M, Heilkenbrinker T, Mumme J.From 1972 to 1991, presecretion on an average of 183 stallions per year had been examined. Facultatively pathogenic germs were ascertained in 13.5% of the samples. However, the portion showed considerable annual fluctuation, as did the percentage of the different kinds of germs. In most of the cases, only minimal growth had been observed in culture. Except for the total percentage, these results are contradictory to those we found during the examination of cervical swabs of mares. In order to ascertain the importance of the respective results and to render possible a correct interpretation, th...
Animal models of Cushing’s disease.
Trends in endocrinology and metabolism: TEM    January 1, 1994   Volume 5, Issue 1 21-28 doi: 10.1016/1043-2760(94)90117-1
Kemppainen RJ, E Peterson M.Cushing's disease, defined as hyperadrenocorticism resulting from excessive secretion of pituitary ACTH, occurs spontaneously and quite commonly in dogs and horses. In dogs, as in humans, the disease is usually associated with a small tumor of the pituitary pars distalis. However, the disease may arise occasionally (dogs) or exclusively (horses) from tumors or hyperplasia of the pituitary pars intermedia. In dogs, pars intermedia tumors may arise from one of two proopiomelanocortin-containing cell types that are present in normal tissue.
The equine placenta and equine chorionic gonadotrophin–an overview.
Experimental and clinical endocrinology    January 1, 1994   Volume 102, Issue 3 235-243 doi: 10.1055/s-0029-1211287
Hoppen HO.Chorionic gonadotrophins seem to be unique for primate and equid species. Unlike primates, the equine conceptus does not implant in the maternal uterine endometrium until around day 37 of pregnancy. At this time specialized cells of the trophoblast, organized in the embryonic girdle, invade the endometrium and become established in the endometrial stroma, forming the so-called endometrial cups. This migration of girdle cells is accompanied by their morphological transformation into large decidual-like cells and by the appearance of a gonadotrophic hormone in the mare's blood. There is convinci...
[Trichinellosis in slaughtered and wild animals in Switzerland using a digestion method and a serologic method (E/S-ELISA)].
Schweizer Archiv fur Tierheilkunde    January 1, 1994   Volume 136, Issue 9 298-308 
Jakob HP, Eckert J, Jemmi T, Gottstein B.For many decades trichinellosis has not been reported among Swiss domestic pigs. Considering the fact that Trichinella occurs in a sylvatic cycle in Switzerland, a study was designed to reevaluate the present epidemiologic situation by investigating 10,904 fattening pigs, 218 pigs with free access to pasturage or being kept on an alp, 104 domestic boars, 106 horses, 44 wild boars and 538 foxes using a direct and an indirect diagnostic technique (digestion method and serology with ELISA and an excretory/secretory antigen, respectively). The digestion method was performed according to EC-guideli...
[A discovery of horseshoes from the 17th century in Kiesen in Bern canton].
Schweizer Archiv fur Tierheilkunde    January 1, 1994   Volume 136, Issue 1 9-14 
Imhof U.The discovery of all four horseshoes in connection with the horse-skeleton (see IMHOF: "Discovery of a skeleton of the 17th century in Kiesen/Switzerland") made it possible to determinate its age by the radiocarbon method indirectly. The horseshoes are fully documented with pictures and scales and the findings described and discussed in detail.
Eccentrocytosis in equine red maple leaf toxicosis.
Veterinary clinical pathology    January 1, 1994   Volume 23, Issue 4 123-127 doi: 10.1111/j.1939-165x.1994.tb00922.x
Reagan WJ, Carter C, Turek J.This study documents a case of red maple leaf toxicosis in a horse, characterized by notable changes in red blood cells, specifically the formation of eccentrocytes, following ingestion of wilted [...]
The relationship of daily sperm production with number of Sertoli cells and testicular size in adult horses: role of primitive spermatogonia.
Journal of reproduction and fertility    January 1, 1994   Volume 100, Issue 1 315-321 doi: 10.1530/jrf.0.1000315
Johnson L, Carter GK, Varner DD, Taylor TS, Blanchard TL, Rembert MS.The number of Sertoli cells is important in spermatogenesis as noted by significant correlations between the number of Sertoli cells and the number of germ cells observed as early as type B2 spermatogonia in the horse. However, the stage within spermatocytogenesis at which these relationships first occur is unclear. The relationships between the number of Sertoli cells and parenchymal weight and the number of germ cells during the mitosis of spermatogenesis were determined in 184 adult horses to identify the developmental stage (that is, the earliest germ cell) at which significant relationshi...
The development of Babesia (Theileria) equi (Laveran, 1901) in the gut and the haemolymph of the vector ticks, Hyalomma species.
Parasitology research    January 1, 1994   Volume 80, Issue 4 297-302 doi: 10.1007/BF02351869
Zapf F, Schein E.The development of the piroplasm Babesia equi was studied by light microscopy in the gut and the haemolymph of three different Hyalomma species during and after the nymphs had engorged on parasitaemic horses. The stock of B. equi used was isolated from a horse imported from Turkmenistan (CIS) in 1991. The existence of gamogony was identified by the occurrence of gamonts and gametes in the gut contents of the nymphs at between 3 and 4 days after infestation of the nymphs, before the ticks dropped off the experimentally infected horses. Zygotes and kinetes were observed in the intestinal cells f...
Assessment of vertebral canal diameter and bony malformations of the cervical part of the spine in horses with cervical stenotic myelopathy.
American journal of veterinary research    January 1, 1994   Volume 55, Issue 1 5-13 
Moore BR, Reed SM, Biller DS, Kohn CW, Weisbrode SE.Magnification of cervical radiographs prevents accurate interpretation of vertebral canal absolute minimum sagittal diameter (MSD) values and application of the established MSD values for diagnosis of cervical stenotic myelopathy (CSM). Variability in MSD determination in human beings, owing to radiographic magnification, is minimized by assessing a ratio of the vertebral canal diameter to the sagittal width of the vertebral body. This relative measurement technique improves the accuracy of diagnosis of cervical spinal stenosis in human beings. The MSD of the vertebral canal was determined in ...
Uremic encephalopathy in a horse.
Veterinary pathology    January 1, 1994   Volume 31, Issue 1 111-115 doi: 10.1177/030098589403100116
Bouchard PR, Weldon AD, Lewis RM, Summers BA.No abstract available
The effects of furosemide and pentoxifylline on the flow properties of equine erythrocytes: in vitro studies.
Veterinary research communications    January 1, 1994   Volume 18, Issue 5 373-381 doi: 10.1007/BF01839288
Weiss DJ, Evanson OA, Geor RJ.The effects of various concentrations of furosemide and pentoxifylline on equine RBC in vitro were evaluated to facilitate better understanding of the potential effects of these drugs on blood flow properties. Furosemide induced increased mean cell volume (MCV), increased RBC potassium concentration, increased whole blood viscosity, and decreased the RBC filtrability. These data indicate that furosemide may block the RBC membrane transport pathways resulting in potassium and water retention. The increase in size and the resultant decrease in the surface-area-to-volume ratio may have caused the...
Molecular cloning and characterization of horse DQA cDNA.
Immunogenetics    January 1, 1994   Volume 40, Issue 6 457 doi: 10.1007/BF00177830
Szalai G, Antczak DF, Gerber H, Lazary S.No abstract available
Immunoreactivity of cytochrome c: antibodies to horse cytochrome c distinguish between sequence-related cytochromes only at the level of the 3-D-structure.
Biochimie    January 1, 1994   Volume 76, Issue 6 465-470 doi: 10.1016/0300-9084(94)90170-8
Leder L, Bosshard HR.It has long been known that antibodies to cytochrome c can distinguish between closely sequence-related cytochromes c. Because the 3-D-structure of the polypeptide chain is virtually identical among eukaryotic cytochromes c, antibody specificity is directed against amino acid substitutions within a common polypeptide folding pattern. The question arises if the specificity is observed at the level of the 3-D-structure (conformational epitopes) and/or at the level of the primary structure (sequential epitopes). Using rabbit sera to horse cytochrome c, we show that discrimination against the host...
Trichinellosis in Greece (1992-1993).
Wiadomosci parazytologiczne    January 1, 1994   Volume 40, Issue 4 396 
Feidas S.No abstract available
Exercise-induced connective tissue turnover and lipid peroxidation in horses.
The British veterinary journal    January 1, 1994   Volume 150, Issue 1 53-63 doi: 10.1016/S0007-1935(05)80096-X
Mills PC, Ng JC, Thornton J, Seawright AA, Auer DE.Four unfit thoroughbred horses were exercised on a treadmill twice, 5 weeks apart. Exercise consisted of stepwise increments in treadmill speed up to a maximum of 12 m s-1 and then maintained at this speed until the horses were fatigued. Two of the horses were administered phenylbutazone (4.4 mg kg-1) intravenously immediately before the first exercise period and the other two horses immediately before the second exercise period. Clinical observation revealed stiffness of gait and palpable soreness over the lumbar-sacral region in the horses 24 h after the exercise concluded. Mean plasma aspar...
Corpus luteal function in nonpregnant mares following intrauterine administration of prostaglandin E(2) or estradiol-17beta.
Theriogenology    January 1, 1994   Volume 42, Issue 7 1069-1083 doi: 10.1016/0093-691x(94)90855-9
Vanderwall DK, Woods GL, Weber JA, Lichtenwalner AB.The objective of this study was to test the hypothesis that intrauterine administration of prostaglandin E(2) (PGE(2)) or estradiol-17beta (E-17beta) would prolong CL function in nonpregnant mares. Nonpregnant mares were continuously infused with 240 mug/d of PGE(2), 6 mug/d of E-17beta, or vehicle (sham-treated) on Days 10 to 16 post ovulation (ovulation = Day 0), using osmotic minipumps surgically placed into the uterine lumen on Day 10 (n = 11 per group). Nonpregnant and pregnant mares served as negative and positive controls, respectively (n = 11 per group). Mares were defined as having pr...
Cholinergic activity of intestinal muscle in vitro taken from horses with and without equine grass sickness.
Veterinary research communications    January 1, 1994   Volume 18, Issue 3 199-207 doi: 10.1007/BF01839269
Murray A, Cottrell DF, Woodman MP.Equine grass sickness (EGS) is a pan-dysautonomia of horses that involves central and peripheral neuronal degeneration and ultimately depletion. This is the first reported functional study on the motility of equine intestine taken immediately post mortem from horses with EGS. Strips of smooth muscle from the small intestine of healthy and EGS-affected horses were suspended in an organ bath and their motility was measured isometrically. The activity of the cholinergic system was studied. Physostigmine enhanced the motility of all muscle strips. Tissues taken from horses suffering from acute gra...
New findings in the development of Babesia (Theileria) equi (Laveran, 1901) in the salivary glands of the vector ticks, Hyalomma species.
Parasitology research    January 1, 1994   Volume 80, Issue 7 543-548 doi: 10.1007/BF00933000
Zapf F, Schein E.The development of the piroplasm Babesia equi was studied by light microscopy in the salivary glands of three different Hyalomma species during and after the engorgement of nymphs on experimentally infected horses and after adults had fed on a vertebrate host following ecdysis. The stock of B. equi used was isolated from a horse imported from Turkmenistan (CIS) in 1991. The findings, being identical in all three Hyalomma species, differ with regard to the chronological order of the development stages in several respects from the results of previous studies based upon light or electron microsco...
Streptococcus pneumoniae and equine disease.
Equine veterinary journal    January 1, 1994   Volume 26, Issue 1 5-6 doi: 10.1111/j.2042-3306.1994.tb04319.x
Chanter N.No abstract available
Evaluation of myeloperoxidase concentrations in experimentally induced equine colonic ischaemia and reperfusion.
Equine veterinary journal    January 1, 1994   Volume 26, Issue 1 67-69 doi: 10.1111/j.2042-3306.1994.tb04334.x
Yarbrough B, Snyder JR, Harmon FA, O'Connell KA.No abstract available
[The emergency stand–a veterinary support apparatus from olden times].
Schweizer Archiv fur Tierheilkunde    January 1, 1994   Volume 136, Issue 1 21-23 
Jenny U.No abstract available