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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Validation of measurable radiographic parameters for quantitative assessment of carpal and metacarpal bone morphology in foals.
Veterinary journal (London, England : 1997)    June 5, 2026   Volume 318 106736 doi: 10.1016/j.tvjl.2026.106736
Son JK, De Paz P, Kim J, Sanaei R, Ryu S, Bailey S, Davies HMS.Radiographic morphometry provides a quantitative means to evaluate bone conformation in horses, yet validation of these parameters in foals has not previously been undertaken. This study aimed to determine the intra- and inter-rater repeatability and reproducibility of established carpal and third metacarpal (MC3) radiographic parameters in Thoroughbred foals and to establish baseline conformational data. Twenty Thoroughbred foals were radiographed without sedation from birth to 14 months of age at two-month intervals. Dorsopalmar carpal and lateromedial MC3 radiographs were obtained using sta...
Syndrome of High Gamma-Glutamyl Transferase in Racehorses.
The Veterinary clinics of North America. Equine practice    June 5, 2026   S0749-0739(26)00024-6 doi: 10.1016/j.cveq.2026.04.009
Haughan J, Cathcart J, Tomlinson JE.Horses in racing and race training can develop high gamma-glutamyl transferase (GGT) syndrome (HGS), or increased GGT without overt evidence of primary liver disease. Current evidence points toward overtraining and a response to oxidative stress, but the etiology is incompletely understood. Evidence for an association of HGS with poor performance is mixed. Without a clear understanding of the etiology, the only evidence-based treatment option is rest or reduced training intensity. More research is needed to determine whether HGS is a physiologic adaptation, perhaps indicative of overtraining b...
Morbidity associated with inhalation anesthesia in horses: the role of opioid use in a university teaching hospital.
Journal of equine veterinary science    June 5, 2026   106055 doi: 10.1016/j.jevs.2026.106055
Cardoso GS, Justo AA, Henriques MAAD, Ferreira MA, Rusch E, Costa FA, Dória RGS, Carregaro AB.Despite concerns among equine practitioners, the effects of opioid administration on intraoperative complications during inhalation anesthesia remain incompletely characterized. This retrospective study evaluated intraoperative complications and perianesthetic mortality in horses undergoing inhalation anesthesia according to opioid use. Medical records from a university veterinary hospital were reviewed (2014-2025) and grouped based on opioid inclusion in anesthetic protocols and surgery type (colic vs. non-colic). Intraoperative hypotension (MAP < 70 mmHg), hypothermia (temperature 65 mmH...
Comparative cardiac histopathology and toxicology screens in horses succumbing to exercise-associated sudden cardiac death and control horses. Diab SS, Giannitti F, Hill A, Morgan J, Blea JA, Arthur R, Poppenga R, Stover S, Uzal FA.Horse racing has faced increased scrutiny because of concerns about equine welfare and the safety of both equine and human participants. Sudden death (SD) in racehorses is relatively uncommon, and its causes are still unclear. Little information and considerable confusion exist regarding the clinical significance of microscopic lesions in the hearts of horses with SD. We examined the hearts of 29 horses that suffered exercise-associated sudden cardiac death (EASCD) and 29 clinically healthy control horses that were euthanized because of catastrophic musculoskeletal injuries. Acute cardiomyocyt...
Evaluation of systemic inflammatory response syndrome criteria in horses with colic associated with acute gastrointestinal disease.
Frontiers in veterinary science    June 4, 2026   Volume 13 1822426 doi: 10.3389/fvets.2026.1822426
Biondi V, Pugliese M, Gambadauro P, Faraci C, Sicuso DA, Bruschetta G, Passantino A, Catone G, Vullo C.Systemic inflammatory response syndrome (SIRS) is a severe clinical condition commonly observed in horses with acute gastrointestinal disease associated with colic and is linked to increased risk of organ dysfunction and mortality. Early identification of SIRS and reliable prognostic indicators are essential to improve clinical management. This study aimed to assess the occurrence of SIRS in adult horses with colic, evaluate its association with outcome, and investigate the prognostic value of selected clinicopathological variables. Unassigned: A total of 41 adult horses admitted for acute gas...
Psycho-Spiritual Reflections on the Horse/Human Relationship.
Psychoanalytic review    June 4, 2026   Volume 113, Issue 2 175-187 doi: 10.1521/prev.2026.113.2.175
Hamm PJ.This essay offers a psycho-spiritual and psychoanalytic meditation on the horse-human relationship as a nonverbal site of attunement, regulation, and meaning-making. Drawing on autobiographical clinical narrative, it explores how horseback riding became a medium for experiencing and reflecting upon embodied connection, mutual responsiveness, and contemplative presence. Encounters with horses illuminate forms of reciprocity that preceded and exceed speech, while also opening reflection on maternal attachment, separation, loss, and the emergence of selfhood. In dialogue with Freud, Winnicott, Pi...
Plasma and urinary exposure of cannabidiol and cannabidiolic acid in horses following consumption of contaminated feed.
Irish veterinary journal    June 4, 2026   doi: 10.1186/s13620-026-00350-6
Ekstrand C, Michanek P, Hernlund E, Gehring R, Salomonsson M.Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive cannabinoids naturally present in hemp-derived products. While these compounds are prohibited during equine competition, horses may be inadvertently exposed through contaminated feed. Data describing systemic and urinary exposure to CBD and CBDA following such low-dose, involuntary intake are limited. This study aimed to describe plasma and urine concentration-time profiles of CBD and CBDA in horses after consumption of experimentally contaminated feed. Results: Twelve Standardbred horses received feed containing low doses (1...
Annual Variation in Stallion Testicular Measurements and Its Association With Hormonal Profiles and Semen Quality.
Reproduction in domestic animals = Zuchthygiene    June 3, 2026   Volume 61, Issue 6 e70244 doi: 10.1111/rda.70244
Braga TRC, Freitas ML, Martins DMV, Viu MAO, Oliveira RA.In a stallion breeding-soundness examination, testicular volume may be estimated either from total scrotal width or by measuring the height, width and length of both testes. This study aimed to determine whether testicular morphometric parameters obtained by ultrasonography fluctuate throughout the year, and whether these variations affect semen quality and hormone production in stallions located at low latitudes in the Southern Hemisphere. Eight healthy light-breed stallions were evaluated every 15 days for 1 year, encompassing the breeding (October-April) and non-breeding(May-September) ...
Assessment of knowledge, attitudes, and preventive practices for equine Endoparasite control among livestock owners in South Gondar Zone, Northwest Ethiopia: A community-based cross-sectional study.
Veterinary parasitology, regional studies and reports    June 3, 2026   Volume 73 101518 doi: 10.1016/j.vprsr.2026.101518
Alemayehu H, Alemneh T, Seyoum Z, Maru M, Ayele A.Endoparasites are a major health concern affecting equine productivity and welfare worldwide. Understanding farmers' knowledge, attitudes, and practices (KAP) toward parasite control is critical for designing effective interventions. This study assessed KAP levels among farmers in South Gondar Zone, Northwest Ethiopia, and identified factors associated with good KAP. A community-based cross-sectional study was conducted among 150 farmers. KAP scores were initially categorized into three levels (low, moderate, and high) and analyzed using chi-square (χ) tests to explore bivariate associations....
Prevalence, risk factors, and antimicrobial resistance of Staphylococcus aureus in equines in Egypt.
Scientific reports    June 3, 2026   Volume 16, Issue 1 17125 doi: 10.1038/s41598-026-55462-4
El-Halim MOA, Shoraba M, Gattan HS, Alruhaili MH, Selim A.Staphylococcus aureus is a common commensal organism in both humans and animals, frequently colonizing the skin and nasal cavities of healthy individuals, although it can also cause a wide range of severe infections. The present study investigated the prevalence and risk factors of S. aureus in equines, along with antimicrobial resistance patterns of methicillin-resistant S. aureus (MRSA) isolates. The results revealed a prevalence of 38.6% in nasal samples collected from equines, highlighting the organism's significant presence and potential to cause infections in these animals. A genotypic p...
Molecular and parasitological evidence of Leishmania (Mundinia) martiniquensis infection in a horse from Brazil.
International journal for parasitology    June 3, 2026   104898 doi: 10.1016/j.ijpara.2026.104898
Franco Leonel JA, Silva MDD, Araujo AC, Vioti G, Borges Martins JP, Strefezzi RF, Galvis-Ovallos F, Bianchi Galati EA, Ferreira de Sousa Oliveira TM.Leishmania (Mundinia) martiniquensis is an emerging human pathogen with increasing reports of infection in domestic animals. This study describes a naturally infected mare from Brazil with no history of international travel, presenting with persistent nodular cutaneous lesions and cervical lymph node enlargement, without evidence of systemic involvement. Considering the endemicity of cutaneous and visceral leishmaniasis in the study area, as well as previous reports of equine leishmaniasis, infection by Leishmania (Leishmania) infantum was initially suspected. Anti-L. (L.) infantum antibodies ...
Case Report: Oral and topical chronic administration of THC-rich and CBD-rich cannabis oil as palliative care in a rescued horse with open wound, sarcoid and chronic pain.
Frontiers in veterinary science    June 2, 2026   Volume 13 1794084 doi: 10.3389/fvets.2026.1794084
Zamith Cunha R, Kuhn EH, Medeiros JLL, Medeiros GC, Amazonas E.Cannabinoid-based therapies have shown analgesic, anti-inflammatory, and wound-healing potential across veterinary species; however, clinical data on long-term use of THC-rich formulations in horses remain scarce. This case report describes the use of combined oral and topical THC-rich and CBD-rich full-spectrum cannabis oils as part of a palliative care strategy in a rescued horse with severe chronic disease. A senior mixed-breed gelding was rescued with a large, chronic ulcerative lesion of the left hind limb, severe malnutrition, non-weight-bearing lameness (AAEP grade 5/5), and refractory ...
Ovum pick-up in mares: Evidence review and best practice recommendations using a modified GRADE approach.
Theriogenology    June 2, 2026   Volume 264 118021 doi: 10.1016/j.theriogenology.2026.118021
Lewis N, Dini P, Spanner J, Claes A, De Grauw J, Morganti M, Daels P, Cuervo-Arango J.Ovum pick-up (OPU) is a procedure that is now performed in mares worldwide to harvest oocytes for in vitro embryo production. There is a lack of consensus surrounding best practices for various procedural elements of the technique and recently there has been an increasing focus on the welfare aspects of the procedure. Our objective was to summarize current practice and to develop guidelines for OPU in the mare, using a modified GRADE approach to optimize efficiency and mare welfare. Published evidence on various aspects of the procedure was compiled, and to supplement the relative lack of publ...
Cerebral arterial mapping in the equine brain: a detailed anatomical study.
Frontiers in veterinary science    June 2, 2026   Volume 13 1828754 doi: 10.3389/fvets.2026.1828754
Al Aiyan A, Abu Hayah S, Alnahdi AF, Alshamsi A, Alshebli H, Aleissaee S, Balan R.Detailed knowledge of the cerebral arterial system in equine brain is required for advancing neuroanatomical understanding and supporting the interpretation of neurological disorders. The equine cerebrum, characterized by extensive cortical organization and functional specialization, requires a continuous arterial blood supply; however, detailed information on its arterial anatomy remains limited. This study aimed to describe the arterial supply to the equine cerebrum, including the origin, branching patterns, and distribution of the major cerebral arteries. Unassigned: Ten adult horse heads w...
Vitrification of in vivo produced equine embryos: Size really does matter!
Journal of equine veterinary science    June 1, 2026   Volume 164 106032 doi: 10.1016/j.jevs.2026.106032
Wilsher S.Vitrification rather than slow-freezing has become the method of choice for the cryopreservation of in-vivo produced embryos. It is a simple technique that does not require a programmable freezing machine and relies chiefly on placing the embryo on a surface, rather than within a straw, in a small volume of vitrification solution to achieve extremely rapid cooling rates. However, in the field of equine embryo vitrification size truly does matter. Methodologies for both vitrification and warming prior to transfer are largely dictated by the size of the embryo. Since embryo size is directly rela...
Short-interval longitudinal analysis of immune cell dynamics in heavy draft foals after colostrum intake.
The Journal of veterinary medical science    June 1, 2026   Volume 88, Issue 8 1134-1143 doi: 10.1292/jvms.26-0023
Yoshida S, Takeyama A, Maeda Y, Nambo Y.Maternal cells and antibodies are present in equine colostrum, but their relationship with immune cells in foals after colostrum ingestion remains unclear. This study longitudinally analyzed immune cells in the peripheral blood of neonatal foals at short intervals and investigated their relationship with colostral immune cells. Eleven clinically healthy draft mares and their foals were examined. Foal blood was collected before colostrum intake (0 hr) and at 2-3, 6, 12, 36-48 hr, and 3 and 7 days after ingestion. Mare blood and milk (0, 36-48 hr; 0 hr milk defined as colostrum) were also collec...
Cheek tooth extraction in geriatric versus non-geriatric horses.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70199
Mair E, Nekouei O, Trummer-Schug P, Haralambus R, Biermann NM.Age-related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population. Objective: To describe clinical features, treatments, complication rates and short-term outcomes of horses undergoing oral cheek tooth extraction and treatment of odontogenic sinusitis, and to compare findings between geriatric and non-geriatric horses. Methods: Retrospective analysis of clinical...
Roux-en-Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70203
Gandini M, Bolz N, Czech C, Hartman M, Giusto G.Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can restore patency but may lead to postoperative complications. Objective: To describe the presentation, surgical management, and postoperative outcome of two horses-an adult and a foal treated with Roux-en-Y gastrojejunostomy combined with a side-to-side jejunojejunostomy (...
Renal Perfusion in Healthy Horses: A Feasibility Study With Contrast-Enhanced Ultrasound. This study assessed the feasibility of contrast-enhanced ultrasound (CEUS) for evaluating renal perfusion in horses and compared perfusion parameters between age groups. In a prospective study, eight healthy horses were divided into young (3-5 years, n = 4) and old (16-17 years, n = 4) groups. All animals underwent B-mode, Doppler ultrasonography, and CEUS of the right kidney after an intravenous bolus of SonoVue (0.02 mL/kg). Qualitative analysis assessed contrast kinetics, whereas quantitative parameters (peak intensity, time to peak [TP], area under the curve, and wash-out time) were o...
Oclacitinib for Controlling Pruritus and Associated Skin Lesions in 16 Horses With Allergic Dermatitis.
Veterinary dermatology    May 31, 2026   doi: 10.1111/vde.70091
Nuchprayoon N, Maneephan P, Tovanakasame N, Kampang C, Jandee P, Sangsuriya P, Tunhikorn M.Oclacitinib is a Janus kinase inhibitor approved for the treatment of pruritus associated with allergic dermatitis in dogs and may be effective in horses. Objective: To evaluate the efficacy of oclacitinib in reducing pruritus and skin lesions in horses with allergic dermatitis. Methods: Sixteen horses aged ≥ 18 months. Methods: Horses received oclacitinib at 0.25 mg/kg orally once daily for 21 days. Changes in haematological and biochemical parameters were measured on Day (D)0 and D21. The owners were instructed to evaluate the horses using the pruritus Visual Analog Scale (PVAS) on...
Laser neoureterocystostomy to treat ectopic ureters.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70201
Smith C, Parente EJ.Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity. Identification of a minimally invasive, effective technique would significantly improve prognosis. Objective: To describe the procedure and outcomes of cystoscopic guided laser neoureterocystostomy in three fillies. Methods: Case series. Methods: Retrospective review of three cases treated wi...
Pathology of sudden death in racehorses: a review. Uzal FA, Asin J, Diab S, Henderson E, Engiles JB, Kennedy L, Schild C.Sudden death (SD) is the second most important syndrome associated with death in racehorses. The cause of SD in a large number of horses remains undetermined, and, in many of these cases, causes are not found by gross or microscopic postmortem examinations. Among the known causes of SD are traumatic injuries, including fractures of skull, neck, and pelvis; intoxications (e.g., anticoagulant rodenticides); and others. For many cases of SD in which no significant lesions are found, heart failure, probably associated with arrhythmias, is suspected. Precise phenotypic characterization of SD in hor...
Management of Equine Post-Extraction Cheek Tooth Alveoli: Application of Alveolar Plugs.
Animals : an open access journal from MDPI    May 30, 2026   Volume 16, Issue 11 1678 doi: 10.3390/ani16111678
Śmich J, Górski K, Maśko M, Borowska M, Turek B, Domino M.Preservation of dentition remains the primary goal of equine dentistry; however, cheek tooth extraction is required in cases of severe dental pathology. Following tooth extraction, management of the post-extraction alveolus remains a significant clinical challenge due to its large size and susceptibility to contamination with feed material and bacteria. To mitigate these risks, alveolar plugs are commonly used to protect the alveolus, stabilize the blood clot, and support granulation tissue formation. This review summarizes the current case reports and research articles regarding the use of al...
Herd-level occurrence and spread of Theileria equi and its associated ticks on an Austrian horse farm.
Veterinary parasitology, regional studies and reports    May 30, 2026   Volume 72 101509 doi: 10.1016/j.vprsr.2026.101509
Pikalo J, Hartl B, Stimac I, Barogh BS, Fuehrer HP, Joachim A.Equine piroplasmosis (EP) is a tick-borne disease caused by the blood parasites Theileria equi, Theileria haneyi, and Babesia caballi transmitted primarily by hard ticks (Ixodidae). The clinical courses of EP range from asymptomatic to severe, and chronic infections for several years support the transmission among hosts. Methods: Over a period of two years, blood and fecal samples were taken from horses (n = 18) on a single farm in eastern Austria, starting with the first confirmed case of T. equi infection. Hard ticks (n = 1525 of Ixodes ricinus, Dermacentor reticulatus and Haemaphysalis ...
Pilot Study of an Alpha-2-Macroglobulin-Enriched Plasma-Derived Orthobiologic Preparation in Sport Horses with Chronic Degenerative Joint Disease.
Veterinary sciences    May 29, 2026   Volume 13, Issue 6 536 doi: 10.3390/vetsci13060536
Gugliandolo E, Biondi V, De Luca M, Nangano E, Strozzi G, Tosto F, Franco GA, Van Reusel Y, Catone G, Spaas JH.Chronic joint disease is a major cause of lameness and reduced performance in sport horses and is characterized by persistent synovial inflammation and protease-mediated matrix degradation. This exploratory prospective pilot study investigated clinical outcomes and synovial biomarker changes following intra-articular administration of an α-2-macroglobulin plasma-derived preparation. Twenty client-owned sport horses were observed in the treatment group (n = 10) or a comparison group (n = 10) and monitored for up to 180 days under field conditions. Clinical outcomes were assessed longitudinally...
Positive Reinforcement (R+) Horse Training in Practice: Evaluation of Online Trailer-Training Demonstrations.
Animals : an open access journal from MDPI    May 29, 2026   Volume 16, Issue 11 1667 doi: 10.3390/ani16111667
Harris HG, McDonnell SM.Operant conditioning that includes primarily positive reinforcement (R+) has been shown to be an effective and welfare-friendly method of training horses. Despite this, operant conditioning and R+ are not fully understood by many horse trainers who claim to advocate for its use. Anecdotal observations suggest that some professional trainers who claim to use R+ do not use R+ primarily, even in publicly offered educational demonstrations. To better understand readily available training materials regarding the use of R+ with horses, we reviewed a sample of 20 online trailer-training demonstration...
Efficacy of 0.5% Tretinoin in the Treatment of Equine Aural Plaques.
Veterinary dermatology    May 29, 2026   doi: 10.1111/vde.70090
de Mattos FS, Conceição LG, Schuartz YGH, Silva VRM, Fidélis CF, Mansur FC, Teixeira CS, Sancler-Silva YFR, Oliveira-Filho JP, Borges AS....Equine aural plaques are a benign form of auricular papillomatosis caused by equine papillomavirus. Despite the efficacy of 5% imiquimod cream, a marked local reaction is frequently observed during therapy, often requiring sedation before application. Objective: The aim of this study was to evaluate the efficacy and potential adverse effects of 0.5% topical tretinoin in the treatment of equine aural plaques. We hypothesised that tretinoin would be effective, with fewer adverse effects compared to imiquimod. Methods: The study included 10 horses of both sexes, aged between 7 months and 15 y...
Do Polish Konik Horses Find Soaked Hay to Be Palatable?
Animals : an open access journal from MDPI    May 29, 2026   Volume 16, Issue 11 1663 doi: 10.3390/ani16111663
Tkaczyk E, Gazda IE, Humięcka M, Łuszczyński J, Basińska K, Kaczmarek B, Barłowska J, Tkaczyk P, Janczarek I.Frequently, equine diseases necessitate the moistening or soaking of hay for the horses. It was assumed that this treatment would not reduce the willingness of the Polish Konik horses with low nutritional requirements to consume the hay. Furthermore, it was believed that moistening would increase the palatability of this feed. The aim of this study was to determine time and frequency parameters and the amount of unconsumed dry, moist, or soaked hay. The research material comprised 12 Polish Konik horses consuming either 1 kg of dry hay, 2.1 kg of moist hay, or 3.3 kg of soaked hay on three sub...
Topical betulinic acid for treatment of equine melanoma and sarcoid.
Frontiers in veterinary science    May 28, 2026   Volume 13 1821503 doi: 10.3389/fvets.2026.1821503
Moreno C, Mudge M, Horne R, Yardley J.Betulinic acid, a natural pentacyclic triterpenoid, has demonstrated anti-inflammatory and anti-tumor properties in vitro, including activity against equine melanoma and sarcoid. However, there is limited in vivo evidence evaluating its clinical efficacy. The objective of this study was to assess the safety and efficacy of a compounded 1% betulinic acid cream for the treatment of equine cutaneous melanoma and sarcoid. Unassigned: This prospective, randomized, double-blinded, placebo-controlled clinical trial enrolled client-owned horses with melanoma or sarcoid tumors. Horses received either a...
Biliary Disorders in Horses.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00020-9 doi: 10.1016/j.cveq.2026.04.005
Peek SF, Sebastian K.This review will mainly focus on the presentation, diagnosis, and treatment of cholangiohepatitis in adult horses. The condition is often accompanied by some degree of intrahepatic and/or extrahepatic biliary obstruction with "sludgy" bile or actual choleliths. In horses, these calculi are typically composed of calcium bilirubinate, rather than cholesterol. There is a propensity for cholangiohepatitis to become a recurrent, chronic condition and patient management should reflect this. Although much rarer, foreign body obstruction, neoplasia and, in some parts of the world, liver flukes can als...