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Topic:Lameness

Lameness in horses is a condition characterized by an abnormal gait or stance due to pain or mechanical dysfunction affecting the limbs or spine. It is a common issue in equine practice and can result from a variety of causes, including injury, infection, or degenerative diseases. Lameness can affect a horse's performance and quality of life, making accurate diagnosis and management important for equine health. Diagnostic techniques often include physical examination, imaging, and gait analysis. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, diagnostic methods, and management strategies for lameness in horses.
Ground Reaction Forces: The Sine Qua Non of Legged Locomotion.
Journal of equine veterinary science    March 6, 2019   Volume 76 25-35 doi: 10.1016/j.jevs.2019.02.022
Clayton HM, Hobbs SJ.Legged locomotion results from the feet pressing against the ground to generate ground reaction forces (GRFs) that are responsible for moving the body. By changing limb coordination patterns and muscle forces, the GRFs are adjusted to allow the horse to move in different gaits, speeds, and directions with appropriate balance and self-carriage. This article describes the typical GRF patterns in each gait, the adaptations that produce turning, and the GRF patterns used to unload the painful limb when the horse is lame. The intent is to provide information that is of practical interest and value ...
Effect of circadian rhythm, age, training and acute lameness on serum concentrations of cartilage oligomeric matrix protein (COMP) neo-epitope in horses.
Equine veterinary journal    March 6, 2019   Volume 51, Issue 5 674-680 doi: 10.1111/evj.13082
Ekman S, Lindahl A, Rüetschi U, Jansson A, Björkman K, Abrahamsson-Aurell K, Björnsdóttir S, Löfgren M, Hultén LM, Skiöldebrand E.Molecular serum markers that can identify early reversible osteoarthritis (OA) in horses are lacking. Objective: We studied serum concentrations of a novel cartilage oligomeric matrix protein (COMP) neo-epitope in horses subjected to short-term exercise and with acute lameness. The effects of circadian rhythm and age were also evaluated. Methods: Longitudinal studies in healthy horses and cross-sectional comparison of lame and non-lame horses. Methods: Sera were collected from five horses before and after short-term interval exercise and during full-day box rest. Sera from 32 acutely lame hors...
Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel in the Management of Joint Lameness in a Population of Flat Racing Thoroughbreds: A Pilot Study.
Journal of equine veterinary science    February 27, 2019   Volume 77 57-62 doi: 10.1016/j.jevs.2019.02.012
de Clifford LT, Lowe JN, McKellar CD, Bolwell C, David F.Osteoarthritis is one of the most common disease processes effecting equine athletes, causing up to 60% of all lameness. This prospective longitudinal study reports on the effect of treatment of carpal and metacarpophalangeal joint lameness with 2.5% cross-linked polyacrylamide hydrogel (PAAG). A total of 49 flat-racing Thoroughbreds at a single training facility were included in the study. The results show a significant improvement in lameness grades at weeks 1 (P < .01), 4 (P < .001), 12 (P < .001), and 24 (P < .001) when compared to baseline lameness at week 0. This pilot study ...
Evaluation of an osteochondral fragment-groove procedure for induction of metacarpophalangeal joint osteoarthritis in horses.
American journal of veterinary research    February 26, 2019   Volume 80, Issue 3 246-258 doi: 10.2460/ajvr.80.3.246
Broeckx SY, Pille F, Buntinx S, Van Brantegem L, Duchateau L, Oosterlinck M, Chiers K, Bertone AL, Spaas JH, Martens AM.OBJECTIVE To evaluate lameness and morphological changes associated with an osteochondral fragment-groove procedure as a means of experimental induction of metacarpophalangeal (MCP) joint osteoarthritis within an 11-week period in horses. ANIMALS 6 nonlame adult warmbloods. PROCEDURES The right MCP joint of each horse underwent an osteochondral fragment-groove procedure (day 0). After 1 week of stall rest (ie, starting day 7), each horse was trained daily on a treadmill. Weekly, horses underwent visual and inertial sensor-based assessments of lameness. Both MCP joints were assessed radiographi...
Health and Body Conditions of Riding School Horses Housed in Groups or Kept in Conventional Tie-Stall/Box Housing.
Animals : an open access journal from MDPI    February 26, 2019   Volume 9, Issue 3 73 doi: 10.3390/ani9030073
Yngvesson J, Rey Torres JC, Lindholm J, Pättiniemi A, Andersson P, Sassner H.We compared welfare measures of horses among Swedish riding schools (RS) during winter where horses were kept either in group housing ( = 8) or in tie-stalls/boxes ( = 8), Health data for six previous months were obtained for all horses at each RS from their records. Ten horses per RS were examined, with the exception of one where only 8 horses were examined. Health conditions and body condition score (BCS) using the Henneke scale were recorded and management factors were quantified (health check routines, feeding, housing-related risk factors, time outside). RS-recorded health data (for 327 h...
Foot abscessation in horses.
The Veterinary record    February 23, 2019   Volume 184, Issue 8 249-250 doi: 10.1136/vr.l316
Barr E.No abstract available
Enhanced ultrasonographic imaging of the equine distal limb using saline injection of the digital flexor tendon sheath: A cadaver study.
Veterinary journal (London, England : 1997)    February 23, 2019   Volume 247 26-31 doi: 10.1016/j.tvjl.2019.02.007
Daniel AJ, Leise BS, Selberg KT, Barrett MF.Injuries to the structures within the digital flexor tendon sheath (DFTS) can lead to lameness with a variable degree of effusion in horses. In some cases, effusion is absent or minimal, and this may be related to the chronicity and type of injury, or veterinary interventions. The purpose of this study was to determine if saline injection into the DFTS would improve ultrasonographic and magnetic resonance imaging of the distal limb without introducing artifact. Nine normal equine cadaver forelimbs were collected. Non-weight-bearing ultrasonographic and magnetic resonance imaging (MRI) examinat...
The Influence of Body Mass and Height on Equine Hoof Conformation and Symmetry.
Journal of equine veterinary science    February 21, 2019   Volume 77 43-49 doi: 10.1016/j.jevs.2019.02.013
Leśniak K, Whittington L, Mapletoft S, Mitchell J, Hancox K, Draper S, Williams J.Despite the likelihood that a horse's mass influences hoof morphology, empirical evidence is lacking. A clearer understanding of factors influencing hoof shape could enable prevention, or better treatment, of foot-based disorders; common causes of equine lameness. The study's aim was to investigate the relationship between horse body size, in terms of mass and height, and fore hoof dimensions. A further aim was to determine changes in the occurrence of hoof asymmetry as body size increases. Height, mass, and fore hoof dimensions; coronet band width (CBW); hoof base width (HBW); dorsal hoof wal...
Musculoskeletal problems associated with lameness and poor performance in cutting horses: 200 cases (2007-2015).
Journal of the American Veterinary Medical Association    February 20, 2019   Volume 254, Issue 5 619-625 doi: 10.2460/javma.254.5.619
Swor TM, Dabareiner RM, Honnas CM, Cohen ND, Black JB.OBJECTIVE To describe the chief complaints by owners and the types and prevalences of musculoskeletal problems associated with lameness or poor performance in cutting horses. DESIGN Retrospective case series. ANIMALS 200 client-owned cutting horses examined at the Texas A&M University Veterinary Medical Teaching Hospital between January 1, 2007, and December 31, 2015, because of lameness or poor performance. PROCEDURES Medical records were reviewed, and data were collected regarding signalment, history, findings on physical and lameness examinations, results of diagnostic procedures performed,...
Variation in gait parameters used for objective lameness assessment in sound horses at the trot on the straight line and the lunge.
Equine veterinary journal    February 12, 2019   Volume 51, Issue 6 831-839 doi: 10.1111/evj.13075
Hardeman AM, Serra Bragança FM, Swagemakers JH, van Weeren PR, Roepstorff L.Objective lameness assessment is gaining more importance in a clinical setting, necessitating availability of reference values. Objective: To investigate the between -path, -trial and -day variation, between and within horses, in the locomotion symmetry of horses in regular use that are perceived sound. Methods: Observational study with replicated measurement sessions. Methods: Twelve owner-sound horses were trotted on the straight line and on the lunge. Kinematic data were collected from these horses using 3D optical motion capture. Examinations were repeated on 12 occasions over the study wh...
Identification of modifiable factors associated with owner-reported equine laminitis in Britain using a web-based cohort study approach.
BMC veterinary research    February 12, 2019   Volume 15, Issue 1 59 doi: 10.1186/s12917-019-1798-8
Pollard D, Wylie CE, Verheyen KLP, Newton JR.Equine laminitis is a complex disease that manifests as pain and lameness in the feet, often with debilitating consequences. There is a paucity of data that accounts for the multifactorial nature of laminitis and considers time-varying covariates that may be associated with disease development; particularly those that are modifiable and present potential interventions. A previous case-control study identified a number of novel, modifiable factors associated with laminitis which warranted further investigation and corroboration. The aim of this study was to identify factors associated with equi...
Science in brief: Progress in endocrinopathic laminitis research: Have we got a foothold?
Equine veterinary journal    February 7, 2019   Volume 51, Issue 2 141-142 doi: 10.1111/evj.13056
de Laat MA.No abstract available
Clinical insights: Diagnosis of laminitis.
Equine veterinary journal    February 7, 2019   Volume 51, Issue 2 143-144 doi: 10.1111/evj.13057
Menzies-Gow NJ.No abstract available
Clinical insights: Treatment of laminitis.
Equine veterinary journal    February 7, 2019   Volume 51, Issue 2 145-146 doi: 10.1111/evj.13055
Bamford NJ.No abstract available
Continuous digital hypothermia prevents lamellar failure in the euglycaemic hyperinsulinaemic clamp model of equine laminitis.
Equine veterinary journal    February 7, 2019   Volume 51, Issue 5 658-664 doi: 10.1111/evj.13072
Stokes SM, Belknap JK, Engiles JB, Stefanovski D, Bertin FR, Medina-Torres CE, Horn R, van Eps AW.Continuous digital hypothermia can prevent the development and progression of laminitis associated with sepsis but its effects on laminitis due to hyperinsulinaemia are unknown. Objective: To determine the effects of continuous digital hypothermia on laminitis development in the euglycaemic hyperinsulinaemic clamp model. Methods: Randomised, controlled (within subject), blinded, experiment. Methods: Eight clinically normal Standardbred horses underwent laminitis induction using the euglycaemic hyperinsulinaemic clamp model (EHC). At initiation of the EHC, one forelimb was continuously cooled (...
Usefulness of caudomedial-craniolateral oblique radiographic views for the diagnosis of injury to the origin of the cranial cruciate ligament in two horses.
Journal of the American Veterinary Medical Association    February 5, 2019   Volume 254, Issue 4 508-511 doi: 10.2460/javma.254.4.508
Aldrich ED, Goodrich LR, Contino EK, Kawcak CE, Barrett MF, King MR, Valdés-Martínez A.CASE DESCRIPTION A 12-year-old mixed-breed mare (horse 1) and 6-year-old Friesian gelding (horse 2) were examined for chronic lameness associated with the stifle joint. CLINICAL FINDINGS Lameness examination revealed effusion of the right (horse 1) or left (horse 2) femoropatellar and medial femorotibial joints and grade 3/5 (horse 1) or 4/5 (horse 2) lameness. A diagnosis of cranial cruciate ligament (CCL) injury with associated mineralization and avulsion (horse 1) or mineralization alone (horse 2) was facilitated in both horses with a caudomedial-craniolateral oblique radiographic view obta...
Phenotypic, hormonal, and clinical characteristics of equine endocrinopathic laminitis.
Journal of veterinary internal medicine    January 29, 2019   Volume 33, Issue 3 1456-1463 doi: 10.1111/jvim.15419
de Laat MA, Sillence MN, Reiche DB.Equine endocrinopathic laminitis is common and can be associated with an underlying endocrinopathy, such as equine metabolic syndrome (EMS), pituitary pars intermedia dysfunction (PPID), pasture consumption, or any combination of these factors. Objective: The aim of the study was to improve the risk assessment capabilities of clinicians, and to inform management strategies, for acute endocrinopathic laminitis by prospectively examining the phenotypic, hormonal, and clinical characteristics of the disease in a large cohort. Methods: Privately owned horses and ponies (n = 301) of any age, se...
Buffering mepivacaine with sodium bicarbonate speeds and potentiates analgesia of median and ulnar nerve blocks performed on horses.
The Veterinary record    January 19, 2019   Volume 184, Issue 5 155 doi: 10.1136/vr.104962
Boone L, Schumacher J, DeGraves F, Cole R.The objective of this study was to determine if buffering mepivacaine HCL (mepHCl) with sodium bicarbonate (NaHCO3) would significantly decrease the time to onset of analgesia when performing median and ulnar nerve blocks in naturally lame horses. Median and ulnar nerve blocks were performed on the naturally lame limb of nine horses during two separate study periods, with a minimum washout period of three days between study periods. Nerve blocks were performed by administering mepHCl alone or mepHCl mixed with NaHCO3 (nine parts 2 per cent mepHCl to one part 8.4 per cent NaHCO3). Lameness was ...
Novel lipoprotein density profiling in laminitic, obese, and healthy horses.
Domestic animal endocrinology    January 18, 2019   Volume 68 92-99 doi: 10.1016/j.domaniend.2018.11.003
Coleman MC, Walzem RL, Kieffer AJ, Minamoto T, Suchodolski J, Cohen ND.Lipoproteins are water-miscible macromolecules enabling the transport of lipids in blood. In humans, altered proportions of lipoproteins are used to detect and classify metabolic diseases. Obesity and obesity-related comorbidities are common in horses. The pathophysiology of obesity is poorly understood and likely multifactorial. Development of new diagnostic tests to identify horses at risk of developing obesity to implement preventative measures is critical; however, a necessary first step to accomplish this goal is to improve our understanding of the pathophysiology of disease. Thus, the ob...
Incidence and clinical signs of owner-reported equine laminitis in a cohort of horses and ponies in Great Britain.
Equine veterinary journal    January 16, 2019   Volume 51, Issue 5 587-594 doi: 10.1111/evj.13059
Pollard D, Wylie CE, Newton JR, Verheyen KLP.Previous robust epidemiological studies of equine laminitis have utilised only veterinary-diagnosed episodes of disease, potentially underestimating true disease frequency. Objective: To estimate the incidence of, and describe clinical signs associated with, owner-reported active laminitis in horses/ponies, using both veterinary-diagnosed and nonveterinary-diagnosed episodes. Methods: Prospective cohort. Methods: Data were collected from horse/pony owners in Great Britain between August 2014 and December 2016 using a web-based application. The incidence of owner-reported laminitis was estimate...
Reliability of equine visual lameness classification.
The Veterinary record    January 13, 2019   Volume 184, Issue 2 60-62 doi: 10.1136/vr.k5366
Keegan KG.No abstract available
Detection of endoplasmic reticulum stress and the unfolded protein response in naturally-occurring endocrinopathic equine laminitis.
BMC veterinary research    January 10, 2019   Volume 15, Issue 1 24 doi: 10.1186/s12917-018-1748-x
Cassimeris L, Engiles JB, Galantino-Homer H.Laminitis is often associated with endocrinopathies that cause hyperinsulinemia and is also induced experimentally by hyperinsulinemia, suggesting that insulin initiates laminitis pathogenesis. Hyperinsulinemia is expected to activate pro-growth and anabolic signaling pathways. We hypothesize that chronic over-stimulation of these pathways in lamellar tissue results in endoplasmic reticulum stress, contributing to tissue pathology, as it does in human metabolic diseases. We tested this hypothesis by asking whether lamellar tissue from horses with naturally-occurring endocrinopathic laminitis s...
Correction: Effects of intrabursal administration of botulinum toxin type B on lameness in horses with degenerative injury to the podotrochlear apparatus.
American journal of veterinary research    January 4, 2019   Volume 80, Issue 1 78 doi: 10.2460/ajvr.80.1.78
No abstract available
Outcome following computed tomographic imaging and subsequent surgical removal of keratomas in equids: 32 cases (2005-2016).
Journal of the American Veterinary Medical Association    January 4, 2019   Volume 254, Issue 2 266-274 doi: 10.2460/javma.254.2.266
Katzman SA, Spriet M, Galuppo LD.OBJECTIVE To describe the use of CT in the diagnosis of and presurgical planning for equids with keratomas treated by hoof wall resection and determine postoperative complications and outcome. DESIGN Retrospective case series. ANIMALS 29 horses and 3 mules with keratomas treated by partial or complete hoof wall resection following CT imaging of the distal portion of the affected extremity from 2005 through 2016. PROCEDURES For each equid, physical examination and lameness evaluation were performed, followed by imaging of the distal portion of the affected extremity. A tentative diagnosis of ke...
Letter to the Editor: A response to ‘What is lameness and what (or who) is the gold standard to detect it?’.
Equine veterinary journal    December 20, 2018   Volume 51, Issue 2 270-272 doi: 10.1111/evj.13043
Adair S, Baus M, Bell R, Boero M, Bussy C, Cardenas F, Casey T, Castro J, Davis W, Erskine M, Farr R, Fischer A, Forbes B, Ford T, Genovese R....No abstract available
An Objective Assessment of the Effect of Anesthetizing the Median Nerve on Lameness Caused by Pain in the Cubital Joint.
Journal of equine veterinary science    December 19, 2018   Volume 75 9-13 doi: 10.1016/j.jevs.2018.12.008
McGlinchey L, Agne G, Passler T, Cole R, Schumacher J.The median nerve, along with the ulnar nerve, is often anesthetized when performing a lameness examination in horses. Because of the close proximity of the median nerve to the cubital joint, proximal migration of local anesthetic might ameliorate pain originating from the cubital joint. The objective of this study was to determine if a median nerve block will ameliorate lameness caused by pain in the cubital joint. A forelimb lameness was induced in six healthy horses by injecting 100 ng of recombinant equine interleukin 1 beta (IL-1β) into the cubital joint. The median nerve of the lame leg...
The expression profile of genes involved in osteoclastogenesis detected in whole blood of Arabian horses during 3 years of competing at race track.
Research in veterinary science    December 18, 2018   Volume 123 59-64 doi: 10.1016/j.rvsc.2018.12.013
Stefaniuk-Szmukier M, Ropka-Molik K, Piórkowska K, Bugno-Poniewierska M.One of the most significant reason of economic loss on race track performance is lame in performed horses. Primarily, due to the failure within proper bone maintenance during conditioning in young horses. The training overload causes bone turnover disturbances in homeostasis between bone resorption and bone formation which promote the bone loss. Within our study we investigated training induced changes in transcript abundance of genes (NFATc1, CTSK, DAP12, CLEC5A, IL6ST, VAV3) involved in osteoclastogenesis hence bone resorption, in whole blood of Arabian horses. The expression pattern of all ...
Contrast enhanced magnetic resonance imaging of the foot in horses using intravenous versus regional intraarterial injection of gadolinium.
Open veterinary journal    December 15, 2018   Volume 8, Issue 4 471-478 doi: 10.4314/ovj.v8i4.19
Zani D, Rabbogliatti V, Ravasio G, Pettinato C, Giancamillo MD, Zani DD.The use of contrast enhanced magnetic resonance imaging (MRI) for the detection of orthopedic pathologies in equine patients is poorly described. In few studies, enhanced MRI allowed to differentiate active lesions from chronic ones and to classify ambiguous lesions. The aim of this clinical prospective pilot study is to describe and compare the MRI lesions observed in horses with lameness localized to the foot using a single intravenous bolus dose of gadolinium contrast versus regional intraarterial bolus of contrast agent. Ten horses that underwent contrast enhanced MRI were included in the ...
The relationship between sagittal hoof conformation and hindlimb lameness in the horse.
Equine veterinary journal    December 15, 2018   Volume 51, Issue 4 464-469 doi: 10.1111/evj.13050
Pezzanite L, Bass L, Kawcak C, Goodrich L, Moorman V.Lameness can be multifactorial and may result from the accumulation of multiple seemingly unrelated causes. The identification of factors associated with lameness could be one method to decrease incidence of lameness and prolong the equine athlete's competitive life. Objective: To determine if there is an association between hoof balance in the sagittal plane and hindlimb lameness. Methods: Case-control study. Methods: Eighty client-owned horses with hindlimb lameness (cases) and 80 horses with no detectable hindlimb lameness (controls) were prospectively enroled following lameness evaluation ...
Factors associated with prolonged treatment days, increased veterinary visits and complications in horses with subsolar abscesses.
The Veterinary record    December 4, 2018   Volume 184, Issue 8 251 doi: 10.1136/vr.104138
Cole SD, Stefanovski D, Towl S, Boyle AG.There is a lack of epidemiological studies about equine subsolar (hoof) abscesses even though they are among one of the most common causes of acute, severe lameness. The goals of this study were to (1) describe the equine subsolar abscess patient population of the University of Pennsylvania's New Bolton Center's Field Service and (2) to determine the factors that are associated with increased veterinary visits, prolonged treatment and complications. Descriptive statistics were performed on data collected from 160 cases of equine subsolar abscess. Inferential statistics were performed on a subs...
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