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Topic:Animal Species
The topic "Animal Species and Horses" explores the interactions and relationships between horses and various other animal species. This includes understanding the ecological roles horses play within their environments, as well as their interactions with domestic and wild animals. Research in this area may cover aspects such as competition for resources, symbiotic relationships, and behavioral influences between horses and other species. Studies may also investigate the impact of horses on biodiversity and ecosystem dynamics. This page compiles peer-reviewed research studies and scholarly articles that examine these interspecies relationships, focusing on the ecological, behavioral, and environmental implications of horses interacting with other animals.
Molecular detection and genotyping of Theileria equi infection within the equine population in Giza, Egypt, using real-time PCR as compared with conventional detection methods. Equine piroplasmosis represents one of the main and serious health problems affecting the equines industry globally, caused by a tick-borne protozoa called and . This study aimed to identify and genotype within the equine population from Giza Governorate, Egypt, by comparing the obtained results using the available diagnostic methods. Unassigned: We collected 116 apparently healthy horses from the study area during the first half of 2019 to identify using real-time PCR (qPCR), targeting the gene. The results were compared with those from microscopic examination of Giemsa-stained blood sme...
Computed Tomographic Assessment of Normal Ocular Dimensions and Densities in Cadaveric Horses (Equus ferus caballus). This study aimed to characterize the computed tomographic (CT) dimensions and contrast attenuation properties of the equine eye. CT scans from 21 horses without ocular abnormalities were analyzed to obtain detailed ocular measurements and attenuation values. In addition, cranial measurements, such as nasal-occipital length and zygomatic width, were incorporated to explore potential anatomical relationships between the skull and intraocular structures. Although most correlations between cranial and ocular parameters were weak, statistically significant associations-particularly those involving ...
Coding-complete genome sequences of group B equine rotavirus from central Kentucky, USA, reveal circulation of a single genome constellation. Equine rotavirus B (ERVB) has caused foal diarrhea in central Kentucky since 2021. Coding-complete genome sequences from 14 strains circulating in 2024 revealed >99% nucleotide identity to the 2021 prototype ERVB strain RVB/Horse-wt/USA/KY1518/2021, with a conserved genomic constellation (G3-P[3]-I3-R3-C3-M3-A4-N3-T3-E3-H3).
Lethal Sycamore maple intoxication in a grazing three-month-old foal. The case of a young foal poisoned by maple toxin is described. It showed signs of myopathy caused by ingesting life-threatening amounts of maple toxin. Some maple trees (Acer species) can pose a health risk to grazing horses. The leaves, seeds and shoots contain hypoglycin A (HGA) and methylencyclopropylglycine (MCPRG) and can cause life-threatening atypical myopathy.
Policresulen is effective for the topical treatment of vaginal varices in a pregnant mare: Case report. Vaginal varicosities in mares are rarely reported, although considered relatively common. Clinical recognition can be challenging, especially during early pregnancy, due to the intermittent nature of the bleeding. This report aims to describe the diagnostic approach, clinical evolution, and treatment of a case of vaginal varicosity in a pregnant mare, emphasizing a practical and minimally invasive method. A 9-year-old Brazilian Sport Horse mare with intermittent vaginal hemorrhage underwent clinical evaluation, showing no abnormalities. Vaginoscopy with a rigid endoscope revealed varicose vein...
Characterization of the lambda light chain repertoire and non-coding regions of equine immunoglobulins using the EquCab3 genome. Horse immunoglobulins have been utilized for over a century in serotherapy to treat venomous animal bites and various other conditions. However, molecular-level information about these immunoglobulins remains limited, particularly regarding immunoglobulin lambda light chains (Igλ), which constitute over 90 % of circulating antibodies. Despite the sequencing of the equine genome, the International ImMunoGeneTics information system (IMGT) has not yet annotated Igλ in its database, restricting the analysis of the horse antibody repertoire. In this study, we analyzed the equine Igλ repertoire...
Arterial distribution to the tensor fasciae antebrachii muscle: a study in dogs, cattle, pigs, and horses. Arterial distribution to the tensor fasciae antebrachii (TFA) muscle is little described in the veterinary literature. In this study, we investigated TFA vascularity intra- and inter-specifically, using specimens obtained from dogs, cattle, pigs, and horses at necropsy. Canine TFA specimens showed vascularity from the collateral ulnar artery in all cases, and from the thoracodorsal artery in some cases, with no brachial or deep brachial arterial vascularity. Bovine TFA specimens showed vascularity from the thoracodorsal artery. All porcine TFA specimens showed deep brachial arterial vascularit...
A de novo FBN1 variant likely causes congenital bilateral ectopia lentis in a crossbred horse. Although several inherited ocular disorders have been extensively studied in horses, few reports of equine ectopia lentis exist and no genetic investigations have been reported. Ectopia lentis in humans and other species is reported to be caused by trauma, genetic variants, and systemic diseases. The most commonly reported genetic causes are dominant alleles in FBN1. Here we examined a 3-day old Oldenburg x Thoroughbred colt due to concerns over bilateral ocular anomalies and hypothesized that either a recessively inherited allele or a dominant de novo allele was the genetic cause. Examination...
Identification and whole-genome characterization of a novel equine papillomavirus. Papillomaviruses (PVs) are small, non-enveloped viruses with double-stranded circular DNA genomes that infect a wide range of hosts, including mammals, birds, reptiles, and fish. While human papillomaviruses are extensively studied, recent advancements in high-throughput sequencing techniques have increased the detection and genetic characterization of PVs from various animal species. Here, we describe the identification and whole-genome characterization of a divergent equine papillomavirus (EcPV) detected through a viral metagenomic investigation of a horse in Denmark exhibiting neurological ...
The Role of Genetic and Environmental Factors in White Leg Markings: Prevalence and Heritability Analysis in Pura Raza Española Horses. White leg markings in horses are phenotypic traits influenced by genetic and environmental factors. This study analyzed their prevalence, symmetry, and genetic parameters in 38,825 Pura Raza Española (PRE) horses registered in the official studbook. White markings were scored using a binary (affected/unaffected) and a four-level ordinal scale. Most horses (38,341 out of 38,825; 98.8%) had at least one limb without white markings. The prevalence of white markings was higher in the hindlegs (17.9% LH; 14.5% RH) than in the forelegs (5.3% LF; 4.6% RF). Markings were most frequent above the fetlo...
Genetic inbreeding depression load for conformation defects and dressage traits in the Pura Raza Española horse. Investigate the genetic inbreeding depression load (IDL) on two dressage traits and two conformational defects in horses. Unassigned: The dataset included performance records for Walk and Points per Reprise (PPR) (N:43,838) and conformation data for Closed and Convergent hocks (N:57,949). Pedigree information spanned over 400,000 individuals. Inbreeding coefficients (F, F6, Fk) and partial inbreeding coefficient (Fij) were computed to quantify the IDL using Bayesian approach. Linear and ordinal logistic regressions were used to assess the relationship between inbreeding and phenotypic values. ...
Integrated molecular and serological survey of Rhodococcus equi in horses from three regions of Kazakhstan. is a facultative intracellular pathogen causing bronchopneumonia in foals; data from Central Asia are limited. We conducted a cross-sectional serological and molecular survey in horses from three regions of Kazakhstan (Kyzylorda, Almaty, Akmola). Unassigned: Sera from 312 animals (272 adults, 40 foals) on 20 farms were tested by indirect ELISA. Selected clinical samples underwent culture, PCR, and 16S rRNA sequencing. Unassigned: Overall seroprevalence was 8.3% (26/312; 95% CI 5.8-11.9). Positivity among foals was 25.0% (10/40; 95% CI 14.2-40.2) versus 5.9% (16/272; 95% CI 3.7-9.3) in adults,...
Early allergen introduction overrides allergy predisposition in offspring of horses with Culicoides hypersensitivity. The origins of allergy are both genetic and environmental. We performed a full-sibling study to determine the role of early-in-life or delayed allergen introduction on hypersensitivity development in a cohort with history of an allergic phenotype and Culicoides hypersensitivity. IgE-mediated allergies naturally develop in many mammalian species, and we used a horse model of allergy called hypersensitivity. hypersensitivity is a seasonal, recurrent, IgE-mediated allergy caused by the salivary proteins of biting midges. Unassigned: The study included four cohorts that lived together in the s...
Lectin Microarray-based Glycomics and Machine Learning Identify Shared Osteoarthritis Biomarkers in Humans, Dogs, and Horses. Post-traumatic osteoarthritis (PTOA) is a common sequela to joint injury in both humans and companion animal species such as horses and dogs. Despite the increasing prevalence of osteoarthritis (OA) in humans, investigation of glycosylation changes associated with OA remains in its infancy. Recent advances, such as lectin microarray analysis, now enable detailed glycan profiling in complex biofluids such as synovial fluid. Using lectin microarray technology, this study characterized glycosylation patterns in synovial fluid samples from healthy and OA-affected joints in horses, dogs, and humans...
Safety and efficacy of a feed additive consisting of an essential oil derived from the flowering aerial parts of Salvia rosmarinus Spenn. (rosemary oil) for use in all animal species (FEFANA asbl). Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the flowering aerial parts of Spenn. (rosemary oil) when used as a sensory additive in feed and in water for drinking for all animal species. Methyleugenol (< 0.039%) and estragole (< 0.027%) were detected in some batches of the additive. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the use of rosemary oil is very unlikely to induce adverse effects in long-living and reproductive ani...
Genome-wide association study reveals candidate loci on ECA1 and ECA9 for withers height in Friesian horses. In Friesian horses, withers height is an important trait as a minimum has been set to be eligible to the studbook. Several loci for withers height have been identified in horses. However, withers height has not been studied in the Friesian horse. Therefore, our aim was to identify loci associated with withers height in the Friesian horse population. We performed a genome-wide association study using 70 K SNP data of 2192 Friesian horses. We found ECA1 and ECA9 to be significantly associated with withers height, explaining 19.6% and 3.5% of the phenotypic variance, respectively. In other hors...
What if Horses Were Humans? Comparing Rein Tension and Bit Pressures to Human Pressure Pain Thresholds. Bit pressure and rein tension-induced mouth pain in horses have recently become a significant welfare concern, fueling debates within the equestrian community and beyond. Evidence indicates that bits can cause pain-related behaviors and even oral lesions. Although studying pressure-induced pain in animals is challenging, the similarities in the physiology of pain processing (nociception) across mammals suggest that it is reasonable to assume that pain perception in humans and horses is principally comparable. Therefore, we compared human pressure pain detection thresholds (PPDTs) to reported r...
Efficacy of feed additives obtained from the leaves of Ginkgo biloba L.: Ginkgo tinctures for all animal species and ginkgo extract for horses, dogs, cats, rabbits and guinea pigs (FEFANA asbl). Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of feed additives obtained from the leaves of L.: ginkgo tinctures as sensory additives for all animal species and ginkgo extract as a sensory additive for horses, dogs, cats, rabbits and guinea pigs. In previous assessments, a sensory analysis of ginkgo extract was performed, which showed that aqueous solutions of ginkgo extract have an intense aroma, significantly different from plain water. No evidence was provided to show that the additives would impart flavour to a food or fee...
Wearable smart textile band for continuous equine health monitoring. Continuous physiological monitoring is well-established in human healthcare for early disease detection and management. However, translation of these technologies to large animals such as equines remains underdeveloped due to anatomical constraints, dense hair coat coverage, and requirements for unimpeded mobility. Equines, particularly racehorses, are prone to asthma and cardiovascular abnormalities, with nearly 80 % affected by mild to moderate asthma, impacting performance and long-term health. Despite the need for continuous monitoring, existing solutions require shaving hairs, often lack...
Molecular Detection and Genetic Characteristics of Equine Herpesviruses 1 and 4 in Egypt. The present study investigated the molecular detection and genetic characteristics of equine herpesvirus 1 (EHV-1) and EHV-4 circulating within Egyptian horse populations during 2019-2022. A total of 79 animals were sampled (54 nasal swabs and 25 aborted fetal tissues). PCR assays revealed that 24 (30.3%) and 7 (8.8%) samples were positive for EHV-1 and EHV-4, respectively. Additionally, 5 (6.3%) samples were concurrently infected with both viruses. Four EHV-1 and three EHV-4 isolates were genetically characterized based on partial sequencing of gB gene. The four EHV-1 strains displayed 100% n...
Dynamic Mobilization Exercises Improve Activity and Stride Parameters Measured with Accelerometry in Sedentary Horses. Dynamic mobilization exercises (DME) are an effective strategy to prevent musculoskeletal injuries and promote back health in sport horses. Previous studies focused mainly on multifidus muscle cross-sectional area, with limited data on locomotion and adaptation timing. This study evaluated locomotor changes using accelerometry, over 8 weeks of DME application in 14 sedentary horses: a DME group ( = 8) performing 10 different DME (3 neck flexions, 1 neck extension and 3 lateral bending exercises to each side), 5 repetitions of each DME per session, 3 sessions/week, and a control group ( = 6), t...
A genome-wide investigation of insidious uveitis in Appaloosa horses. Equine recurrent uveitis (ERU), an inflammatory eye disease, is the leading cause of blindness among horses. Insidious uveitis, a form of ERU, is especially pervasive within the Appaloosa breed and is highly heritable (h = 0.68-1.0). To date only one risk locus, leopard complex (LP), has been identified, and it explained 0.16-0.33 of the heritability estimate, suggesting that insidious uveitis is a complex genetic disease within the Appaloosa horse breed with multiple unknown predisposing loci. Results: A genome-wide association study (GWAS) using relatedness, LP genotype, sex, and age as ...
Equine Metabolism of Voxelotor and Its Impact on Hematological Indices: A Doping Control Perspective. Voxelotor, a therapeutic drug for sickle cell disease, has been reported to elevate serum erythropoietin and hemoglobin levels in healthy individuals. Because of its potential to alter blood parameters, the World Anti-Doping Agency (WADA) classified voxelotor under category M1 of the 2023 Prohibited List. Despite this classification, little is known about its metabolic behavior in either humans or animals. In this study, the metabolism of voxelotor was investigated in Thoroughbred horses after oral administration. Using liquid chromatography high-resolution mass spectrometry (LC-HRMS), 35 meta...
Species diversity and within-host tropism for mixed equine strongyle infections using a cytochrome c oxidase subunit I metabarcoding approach. Strongyles, especially non-migratory Strongylidae, are the most common equine gut parasites, and typically occur in mixed infections with 10 - 20 species per host. Current knowledge on strongyle species prevalence and within-host tropism is sparse. Herein species composition of mixed strongyle infections of 12 naturally infected untreated young horses, based on strongyle eggs extracted from faeces, cultured third stage larva and luminal worms collected from ventral and dorsal colon was examined. Species were identified using a cytochrome c oxidase I (COI) metabarcoding approach allowing differ...
Adverse Effects of Antimicrobial Drugs Use in Horses. Antimicrobial drug therapy in horses can lead to adverse effects across multiple body systems, with specific age groups, such as foals, at particular risk. Certain antimicrobial drugs, such as penicillins, aminoglycosides, macrolides, tetracyclines, and trimethoprim-sulfonamide combinations, are commonly implicated. This review explores the mechanisms behind these adverse reactions, emphasizing the importance of judicious antimicrobial drug use. This review also underscores the need for a centralized pharmacovigilance system to improve drug safety and adverse event reporting for veterinary med...
Intraday and Interday Evaluation of pH and Hydrogen Peroxide in the Exhaled Breath Condensate of Horses Using A Portable Device. The analysis of equine exhaled breath condensate (EBC) lacks standardized methodology, and current collection devices are often adapted for research. This study evaluates a novel horse-specific EBC collector and assesses the variability of EBC pH and hydrogen peroxide (HO) levels, exploring potential correlations with bronchoalveolar lavage (BAL) and tracheal wash (TW) cytology. Eleven healthy mixed-breed mares from a teaching herd, with no evidence of airway abnormalities, were included in this randomized observational study. The collection efficiency of the proposed device was assessed, and ...
Hematological and blood biochemical parameters of Tokara horses in Kaimon Foothills Nature Park. The Tokara horse is a breed of native Japanese horse, for which hematological and biochemical data are lacking. The aim of this study was to obtain current hematological and biochemical data on Tokara horses. We enrolled 90 Tokara horses kept at the Kaimon Foothills Nature Park (Kagoshima) that underwent physical examinations and blood sampling between 2022 and 2024. All horses in this study were regarded as clinically healthy, based on physical examinations. Hematological and biochemical parameters also showed no abnormal values. Based on the above results, we consider that the data from this...
First report of West Nile virus infections in horses in Tunisia from 2018 to 2023. West Nile virus (WNV) is an arthropod borne virus, the most widely distributed of the encephalitic Orthoflaviviruses. It can cause severe neurological symptoms in both humans and horses. It poses an emerging threat to both public and animal health. In this study, we retrospectively screened 25 suspected WNV samples collected from 2018 to 2023. Methods: A total number of 25 samples (brain tissue and blood) were collected from clinically affected horses and those already deceased across several locations in Tunisia. All samples were tested for the presence of WNV NS2A gene using qRT-PCR. Eleven ...
Mapping the Metabolic Fate of Suzetrigine in Equine and Camel Models: A Step Toward Reliable Antidoping Detection. Effective pain management remains a persistent challenge, with opioids limited by tolerance, dependence, respiratory depression, and misuse. This has created demand for safer, nonaddictive alternatives. Suzetrigine (VX-548, Journavx) is a novel analgesic with promising efficacy, but its potential misuse in competitive racing requires investigation. Limited information is available on its metabolism and detection, emphasizing the need for metabolic characterization to aid antidoping strategies. Methods: In vitro metabolism of suzetrigine was evaluated using equine liver microsomes and homogeniz...
