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Topic:Safety

Safety in horses encompasses practices, equipment, and protocols designed to prevent accidents and injuries to both horses and humans. It involves understanding equine behavior, proper handling techniques, and the use of protective gear. Safety measures include the correct fitting and use of tack, appropriate rider attire such as helmets and boots, and safe stable management practices. This topic also covers the design of equestrian facilities to minimize hazards and the implementation of emergency procedures. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of equine safety, including risk factors, preventive strategies, and the effectiveness of safety interventions in equestrian activities.
Electrochemotherapy with bleomycin for bilateral ocular squamous cell carcinoma in a horse.
Veterinary ophthalmology    December 16, 2024   doi: 10.1111/vop.13310
Larsen MME, Eriksson A, Impellizeri JA.To describe the procedure and outcome of electrochemotherapy (ECT) with bleomycin as a first-line treatment for bilateral ocular surface squamous neoplasia (OSSN) in the eye of a horse. Methods: A client-owned 5-year-old Haflinger gelding with limbal-conjunctival squamous cell carcinoma. Methods: During general and local anesthesia, injection of bleomycin in the ocular tumor was followed by electroporation, applied with a 15 mm needle electrode, needles held parallel to the ocular surface. Results: Treatment with ECT resulted in therapeutic electric pulses and complete tumor response with no...
Stakeholder Views on the Potential Benefits and Feasibility of an Equestrian Industry-Specific Health, Safety and Welfare Management System.
Animals : an open access journal from MDPI    November 28, 2024   Volume 14, Issue 23 3450 doi: 10.3390/ani14233450
Chapman M, Fenner K, Thomas MJW, Thompson K.With the growth of the equestrian industry, risk exposure and the obligation to maintain the health, safety, and welfare of humans and horses remain front and centre. As there has been no apparent reduction in non-fatal human horse-related injuries, we asked industry stakeholders to discuss their current management and risk mitigation practices and highlight potential barriers to improving these processes. Semi-structured interviews were conducted with 20 stakeholders from Australian equestrian work- ( = 9) and non-work- ( = 11) related organisations to determine the potential benefits and fea...
Safety and efficacy of a feed additive consisting of an essential oil derived from the flowering stems of Salvia sclarea L. (clary sage oil) for use in all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    November 14, 2024   Volume 22, Issue 11 e9016 doi: 10.2903/j.efsa.2024.9016
Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the fresh or dried flowering stems of L. (clary sage oil) when used as a sensory additive in feed and in water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive under assessment is considered safe up to the maximum use level in complete feed of 15 mg/kg for veal calves (milk replacers), cattle for fattening, sheep/goats, 10 mg/kg for horses, 20 mg/k...
Assessment of the modification of the authorisation of the feed additive consisting of Saccharomyces cerevisiae CNCM I-1077 for lambs and its extension of use to all ruminants and camelids reared for milk production/suckling/reproduction, all minor (young) ruminant species and camelids for fattening and Equidae other than horses (Lallemand SAS).
EFSA journal. European Food Safety Authority    November 13, 2024   Volume 22, Issue 11 e9075 doi: 10.2903/j.efsa.2024.9075
Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a preparation of CNCM I-1077 as a zootechnical feed additive for several animal species. The additive, existing in a not-coated and a coated form, is currently authorised for use in feed for calves, cattle for fattening, dairy cows, dairy goats and dairy sheep, lambs, all minor ruminant species for fattening and rearing, horses and camelids for fattening and rearing. This application regards the request for the extension of use in all ruminants and camelids reared for...
Does Equestrian Helmet Type Affect Head Injury? A Study on Equestrian Helmet Use Among Collegiate Athletes.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine    November 5, 2024   Volume 35, Issue 6 646-651 doi: 10.1097/JSM.0000000000001297
Gould S, Crawford AE, Picken L, Serrano D, Gabriel F, McGwin G, Chandran A, Schrum K.To characterize helmet use, head injury risk, and to examine rider-related factors that influence these variables. Methods: Cross-sectional study. Methods: The University of Alabama at Birmingham Equestrian Sports Medicine Collaborative. Methods: In total, 357 equestrians competing at the collegiate level participated in this study. Unassigned: χ 2 tests were used to evaluate potential associations between a rider's experience level, riding style, and use of helmet designed with MIPS with number of falls, past head injuries, and helmet use frequency. Methods: Data regarding helmet use and equ...
A threshold model to determine the association between race rides and fall risk for early career (apprentice) jockeys.
Journal of science and medicine in sport    October 31, 2024   Volume 28, Issue 4 292-297 doi: 10.1016/j.jsams.2024.10.009
Legg KA, Cochrane DJ, Gee EK, Rogers CW.To identify descriptors associated with success in apprentice jockeys and to determine optimum numbers of jockeys for safer race riding. Methods: Retrospective cohort study. Methods: Incidence-rates for jockey falls and success (wins per 1,000 race-starts), time and number of races spent at different apprentice levels were calculated for 807 apprentice and professional jockeys over 19 years of Thoroughbred flat racing in New Zealand (n = 524,551 race-starts). Survival analysis was used to compare career progression for jockeys that fell and those that did not, and individual seasonal fal...
Safety and efficacy of a feed additive consisting of an essential oil derived from leaves and terminal branchlets of Melaleuca alternifolia (Maiden & Betche) Cheel (tea tree oil) for use in all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    October 28, 2024   Volume 22, Issue 10 e9026 doi: 10.2903/j.efsa.2024.9026
Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of tea tree oil obtained from leaves and terminal branchlets of (Maiden & Betche) Cheel when used as a sensory additive for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that tea tree oil was very unlikely to be of safety concern for long-living and reproductive animals and is of no concern for target species for fattening at the following concentrations in complete feed: 1.1 mg/kg for chickens for f...
Safety and efficacy of a feed additive consisting of an essential oil derived from the flowering tops of Thymbra capitata (L.) Cav. (Spanish type origanum oil) for use in all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    October 28, 2024   Volume 22, Issue 10 e9018 doi: 10.2903/j.efsa.2024.9018
Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the flowering tops of (L.) Cav. (Spanish type origanum oil) when used as a sensory additive in feed and in water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive under assessment is considered safe up to the maximum use level in complete feed of 15 mg/kg for poultry species, 30 mg/kg for pigs and horses, 20 mg/kg for ruminants, 25 mg/kg for rabbits...
Equestrian-associated injuries of the hand: a retrospective analysis of injury mechanisms and patterns.
Archives of orthopaedic and trauma surgery    October 17, 2024   Volume 144, Issue 11 4937-4945 doi: 10.1007/s00402-024-05586-x
Ritter B, Dastagir N, Tamulevicius M, Bucher F, Obed D, Vogt PM, Dastagir K.Hand injuries are frequently caused by sports and are associated with long periods of inability to work and high economic health costs. After ball sports and cycling, the most common cause of hand injuries is horseback riding. Therefore, measures should be taken to prevent these risks and increase safety in sports, however data characterizing equestrian sports-associated injuries are limited. Methods: A retrospective monocentric cohort study was performed including 39 patients (mean age: 35 ± 2.6 (range 9-65) years, female 89.7% who sustained an injury to the hand while practicing equestr...
Computed tomography of the equine caudal spine and pelvis: Technique, image quality and anatomical variation in 56 clinical cases (2018-2023).
Equine veterinary journal    October 10, 2024   Volume 57, Issue 5 1265-1278 doi: 10.1111/evj.14422
Ogden NKE, Winderickx K, Bennell A, Stack JD.Cross-sectional imaging improves the diagnostic accuracy of complex anatomical regions. Computed tomography (CT) of the pelvis and caudal spine in a large group of live horses and ponies has not been previously reported. Objective: To describe the procedure for acquiring CT images of horses' caudal spine/pelvis under general anaesthesia (GA) and to detail the image quality, artefacts and anatomical variations in this region. Methods: Retrospective case series. Methods: Horses with CT of the caudal spine/pelvis were included. Horses under 6 months and CT examination performed post-mortem were...
Radiation exposure during simulated equine head and limb fan beam standing computed tomography appears safe for personnel using lead shielding.
Journal of the American Veterinary Medical Association    September 20, 2024   Volume 263, Issue 1 63-70 doi: 10.2460/javma.24.06.0424
Veitch KE, Szczykutowicz TP, Brounts SH, Ergun DL, Muir P, Loeber SJ.To evaluate the radiation dose to personnel locations during simulated head and limb scans with a novel equine standing CT (sCT) system. Methods: Measurements were made with the use of a helical fan beam sCT system (Equina; Asto CT Inc). Scatter radiation was measured in different positions in the sCT room to mimic the location of the control operator, horse handler, and lead rope handler during simulated equine head and limb imaging. Operator/handler dose was quantified at each location using entrance air kerma measured with a spherical ionization chamber and electrometer. Results: Radiation ...
Characteristics of equestrian accidents and injuries leading to permanent medical impairment.
BMC sports science, medicine & rehabilitation    September 4, 2024   Volume 16, Issue 1 184 doi: 10.1186/s13102-024-00973-8
Stigson H, Klingegård M.Equestrian sports, also referred to as equestrianism, is practiced all over the world and a popular leisure activity in Sweden. Equestrianism is the country's second-largest youth sport, and previous studies indicate that accidents are common in equestrianism. However, few previous studies have examined acute equestrian injuries leading to permanent medical impairment (PMI). Methods: By using nationwide insurance data comprising all injured equestrians registered in the Swedish Equestrian Federation, the aim was to analyse characteristics of equestrian accidents and particularly injuries leadi...
Intra-uterine injection of amnion-derived acellular bioscaffold product in mares, a description of systemic and intra-uterine effects over 21 days.
Journal of equine veterinary science    August 30, 2024   Volume 142 105180 doi: 10.1016/j.jevs.2024.105180
Kelley D, Walbornn S, Bartley C, Kaczor J, Premanandan C, Newton N, Holland R, Schnobrich M.Amnion-derived acellular bioscaffold (ADABP) products demonstrate interesting anti-inflammatory and healing properties which could be beneficial for intrauterine use. The objective of this study was to evaluate the safety of intrauterine injection of ADABP on systemic and uterine health. The study design randomly assigned subjects to one of two groups, control mares (n = 3) which received 3 mL injection of sterile saline in the base of each uterine horn, and treatment mares (n = 9) which received 3 mL of ADABP in the base of one uterine horn and 3 mL injection of sterile saline in the base of ...
CNS and Thorax Injury and Associated Risks Factors in Equestrian Sports.
Sports health    August 29, 2024   19417381241275655 doi: 10.1177/19417381241275655
Crawford AE, Picken LK, Gabriel FD, Quade J, Gould S.Equestrian sports continue to gain popularity in the United States and are associated with a high injury rate, especially involving the central nervous system and thorax. Due to this high rate of injury and the potential for long-term consequences associated with participation, an understanding of the unique risks of this sport is needed. Unassigned: To describe severe injury in equestrian sports and review the role that protective gear plays in injury mitigation. Unassigned: The PubMed Database was searched using the search terms "equestrian" and "horse" combined with "spinal cord injury," "h...
Chemotherapeutics in Equine Practice.
The Veterinary clinics of North America. Equine practice    August 17, 2024   Volume 40, Issue 3 387-395 doi: 10.1016/j.cveq.2024.07.004
Malalana F.Chemotherapy is the treatment of cancerous cells through the use of cytotoxic drugs. Whilst the use of systemic (intravenous) chemotherapy in equine practice is generally limited to the management of lymphoma, cytotoxic drugs are commonly used in the treatment of accessible skin tumors, either by topical application in the form of ointments or injected intralesionally. These drugs should be employed with caution due to the risk of serious adverse effects. In addition, extreme caution should be followed when preparing, handling, administering, and disposing them, due to their carcinogenic, muta...
Safety and efficacy of a feed additive consisting of an essential oil obtained from the fruit of Carum carvi L. (caraway oil) for all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    July 31, 2024   Volume 22, Issue 7 e8906 doi: 10.2903/j.efsa.2024.8906
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil obtained from the fruit of L. (caraway oil), when used as a sensory additive in feed and water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Panel concluded that the use of caraway oil is of no concern up to the following concentrations in complete feed: 9 mg/kg for chickens for fattening, 13 mg/kg for laying hens, 12 mg/kg for turkeys for fattening, 16 mg/kg for piglets, 19 mg...
Safety and efficacy of a feed additive consisting of an essential oil obtained from the fruit of Apium graveolens L. (celery seed oil) for all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    July 25, 2024   Volume 22, Issue 7 e8907 doi: 10.2903/j.efsa.2024.8907
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil obtained from the fruit of L. (celery seed oil), when used as a sensory additive in feed and water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Panel concluded that the use of celery seed oil is of no concern up to the following concentrations in complete feed: 1.6 mg/kg for chickens for fattening, 2.3 mg/kg for laying hens, 2.1 mg/kg for turkeys for fattening, 2.8 mg/kg for p...
Safety and efficacy of a feed additive consisting of sodium ferrocyanide and potassium ferrocyanide for all animal species (Eusalt a.i.s.b.l.).
EFSA journal. European Food Safety Authority    July 12, 2024   Volume 22, Issue 7 e8851 doi: 10.2903/j.efsa.2024.8851
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of sodium ferrocyanide and potassium ferrocyanide as technological feed additives for all animal species. In its previous opinion on the safety and efficacy of the additives, the FEEDAP Panel concluded that the use of sodium ferrocyanide and potassium ferrocyanide is safe, when added to sodium chloride at a maximum content of 80 mg ferrocyanide anions (anhydrous)/kg for turkeys for fattening and laying hens and other laying/breeding birds, all porcine species and categori...
Airbag Vests in Equestrian Sports: Is Use Associated with Harm?
Annals of biomedical engineering    July 2, 2024   Volume 52, Issue 11 2916-2922 doi: 10.1007/s10439-024-03507-y
Meyer C, Gabriel F, Schrum K, Hollis M, Short M, Gould S.Airbag vests (AV) are increasingly popular in equestrian sports. The efficacy of AV in protecting against serious injury has not been adequately analyzed, nor have product testing standards been established. This study provides an overview of current research to understand AV efficacy and future areas of improvement. A systematic review applying the PRISMA framework, NIH Study Quality Assessment, and CEBM Level of Evidence was conducted. Employing variations of "equestrian sport," "powered two-wheeled vehicle," "thoracic injury," "chest deflection," "airbag vest," and "safety vest," 18 article...
Intra-articular injection of an extended-release flavopiridol formulation represents a potential alternative to other intra-articular medications for treating equine joint disease.
American journal of veterinary research    June 21, 2024   Volume 85, Issue 9 doi: 10.2460/ajvr.24.03.0057
Katzman SA, Cissell D, Leale D, Perez-Nogues M, Hall MD, Bloom G, Hamamoto-Hardman B, Wu CY, Haudenschild AK, Liu GY, Yik JHN, Haudenschild DR.To establish the pharmacokinetics of the cyclin-dependent kinase-9 inhibitor flavopiridol in equine middle carpal joints, using an extended-release poly lactic-co-glycolic acid (PLGA) microparticle formulation. Methods: 4 healthy horses without evidence of forelimb lameness. Methods: A 6-week longitudinal pharmacokinetic study was conducted in 2 phases (6 weeks each) in 4 healthy horses. The PLGA microparticles containing 122 μg flavopiridol in 3 mL saline were administered by intra-articular injection into 1 middle carpal joint, with empty PLGA microparticles injected into the contralateral ...
Hematological and Biochemical Effects Associated with Prolonged Administration of the NSAID Firocoxib in Adult Healthy Horses.
Veterinary sciences    June 5, 2024   Volume 11, Issue 6 doi: 10.3390/vetsci11060256
Ignácio FS, Garcia LV, de Souza GG, Amatti LZ, de Barros LD, Bergfelt DR, Camargo GS, de Meira C, de Almeida BFM.Non-steroidal anti-inflammatory drugs (NSAIDs) represent one of the most commonly used classes of drugs in both human and veterinary medicine. However, many clinical side effects have been observed, especially when treatment has been prolonged. While the anti-inflammatory efficacy and safety of repeated administration of firocoxib (Previcox®), which is a selective NSAID COX-2 inhibitor, has been evaluated for short-term use (one to fourteen days), its clinical relevance for longer-term use is not known. As a preliminary study, healthy, adult male and female horses (n = 7) were treated with fi...
Craniofacial Trauma of Equestrian Origin.
The Journal of craniofacial surgery    May 29, 2024   Volume 35, Issue 6 1607-1611 doi: 10.1097/SCS.0000000000010126
Boiron A, Barazer C, Clement C, Sahli Vivicorsi S, Bellamy L, Le Toux G, Boisramé S.Horse riding is a popular yet dangerous sport, often resulting in facial traumas due to unpredictable horse reactions or falls. This retrospective study examines 20 patients. The aim of the study is to analyze maxillofacial traumas of equine origin and discuss prevention strategies. Conducted from 2004 to 2021 at our university hospital's emergency department in France, inclusion criteria encompassed patients with maxillofacial trauma admitted to the emergency department and referred to ENT and/or dentistry post-horse-related accidents. Patients were identified from the Health Data warehouse. ...
Stability and Detection Limit of Avian Influenza, Newcastle Disease Virus, and African Horse Sickness Virus on Flinders Technology Associates Card by Conventional Polymerase Chain Reaction.
Animals : an open access journal from MDPI    April 21, 2024   Volume 14, Issue 8 doi: 10.3390/ani14081242
Taesuji M, Rattanamas K, Yim PB, Ruenphet S.The Flinders Technology Associates (FTA) card, a cotton-based cellulose membrane impregnated with a chaotropic agent, effectively inactivates infectious microorganisms, lyses cellular material, and fixes nucleic acid. The aim of this study is to assess the stability and detection limit of various RNA viruses, especially the avian influenza virus (AIV), Newcastle disease virus (NDV), and African horse sickness virus (AHSV), on the FTA card, which could significantly impact virus storage and transport practices. To achieve this, each virus dilution was inoculated onto an FTA card and stored at r...
Safety and efficacy of a feed additive consisting of a tincture derived from the dried fruit of Schisandra chinensis (Turcz.) Baill. (omicha tincture) for poultry, horses, dogs and cats (FEFANA asbl).
EFSA journal. European Food Safety Authority    April 10, 2024   Volume 22, Issue 4 e8731 doi: 10.2903/j.efsa.2024.8731
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, Puente SL, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a tincture from the dried fruit of (Turcz.) Baill. (omicha tincture), when used as a sensory additive in feed for horses, cats, dogs, and in feed and in water for drinking for poultry. The product is a water/ethanol (55:45 v/v) solution, with a dry matter content of not more than 4% (w/w) and a content of 0.01%-0.15% (w/w) for the sum of schisandrin and deoxyschisandrin. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that omic...
Safety and efficacy of a feed additive consisting of a dry extract obtained from the leaves of Ginkgo biloba L. (ginkgo extract) for horses, dogs, cats, rabbits and guinea pigs (FEFANA asbl).
EFSA journal. European Food Safety Authority    April 10, 2024   Volume 22, Issue 4 e8733 doi: 10.2903/j.efsa.2024.8733
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive obtained from the dried leaves of L. (ginkgo extract) when used as a sensory additive in feed for horses, dogs, cats, rabbits and guinea pigs. Ginkgo extract contains ≥ 24% total flavonoids, ≥ 6% total terpene lactones and ≤ 1 mg/kg ginkgolic acids. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that ginkgo extract is safe for the target species at the following concentrations in complete fee...
Safety and efficacy of a feed additive consisting of an essential oil derived from fresh leaves of Melaleuca cajuputi Maton & Sm. ex R. Powell and Melaleuca leucadendra (L.) L. (cajuput oil) for use in all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    April 10, 2024   Volume 22, Issue 4 e8732 doi: 10.2903/j.efsa.2024.8732
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, Puente SL, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F....Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of cajuput oil obtained from fresh leaves of Maton & Sm. ex R. Powell and (L.) L., when used as a sensory additive for all animal species. The FEEDAP Panel concluded that cajuput oil is safe up to the maximum proposed use levels in complete feed of 30 mg/kg for sows and dogs, 50 mg/kg for horses and ornamental fish, 40 mg/kg for salmon and 5 mg/kg for cats. For the other species, ...
Equine bone marrow MSC-derived extracellular vesicles mitigate the inflammatory effects of interleukin-1β on navicular tissues in vitro.
Equine veterinary journal    April 8, 2024   doi: 10.1111/evj.14090
Quam VG, Belacic ZA, Long S, Rice HC, Dhar MS, Durgam S.Safe, efficacious therapy for treating degenerate deep digital flexor tendon (DDFT) and navicular bone fibrocartilage (NBF) in navicular horses is critically necessary. While archetypal orthobiologic therapies for navicular disease are used empirically, their safety and efficacy are unknown. Mesenchymal stem cell-derived extracellular vesicles (EV) may overcome several limitations of current orthobiologic therapies. Objective: To (1) characterise cytokine and growth factor profiles of equine bone marrow mesenchymal stem cell (BM-MSC)-derived extracellular vesicles (BM-EV) and (2) evaluate the ...
Safety and efficacy of a feed additive consisting of a tincture derived from the roots of Panax ginseng C.A.Mey. (ginseng tincture) for horses, dogs and cats (FEFANA asbl).
EFSA journal. European Food Safety Authority    April 8, 2024   Volume 22, Issue 4 e8730 doi: 10.2903/j.efsa.2024.8730
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, Puente SL, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a tincture from the roots of C.A.Mey. (ginseng tincture), when used as a sensory additive in feed for horses, dogs and cats. The product is a water/ethanol (40:60 v/v) solution, with a dry matter content of no more than 6% and a content of 0.01%-0.5% (w/w) for the sum of the two triterpene saponins ginsenoside Rb1 and ginsenoside Rg1. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the tincture is safe for horses, dogs and...
Diamond burr debridement of calcific band keratopathy in 24 eyes of 22 horses.
Veterinary ophthalmology    March 26, 2024   Volume 27, Issue 6 549-557 doi: 10.1111/vop.13212
Jugant S, Regnier A, Douet JY.To evaluate the safety and effectiveness of diamond burr debridement (DBD) for the treatment of calcific band keratopathy (CBK) in horses. Methods: Medical records from horses with CBK were reviewed over a period of 4 years. Diagnosis of CBK was based on slit-lamp examination findings, and DBD was performed on standing sedated horses. Follow-up was obtained by clinical reevaluation of the treated eyes or a telephone survey with the referring veterinarian. Results: Twenty-two horses of different ages (median: 11 years; range: 5-23) representing 24 CBK-affected eyes (14 left eyes and 10 righ...
Review of cellular therapies provides new insights into the potential treatment of diverse neurologic diseases in horses and dogs.
Journal of the American Veterinary Medical Association    March 8, 2024   1-10 doi: 10.2460/javma.23.12.0709
Colbath AC, Goodrich L, Frye C, Dow S.Neurological diseases and injuries in veterinary patients (horses, dogs, and cats) are complex, and effective treatment options are limited. Neuronal loss, damage to nerve conduction pathways, and inflammation and scarring associated with spinal cord injury pose major challenges in managing many neurological diseases. Furthermore, most of these neuropathologies lack definitive pharmacological treatments, driving interest and research into novel interventions. Our objective is to provide a narrative review of the current literature surrounding cellular therapies including neuronal and glial ste...