Medications

Fluoxetine, commonly known by the trade name Prozac®, is a medication increasingly discussed in equine practice as an option for managing behavioral challenges in horses. As a selective serotonin reuptake inhibitor (SSRI), it works by increasing serotonin levels in the...

Oxytocin is a naturally occurring hormone used in horses to stimulate uterine contractions and milk letdown. In clinical practice, it is commonly used to support reproductive processes such as uterine clearance after breeding, expulsion of retained placenta after foaling, and...

Hydroxyzine, sold under the brand name Vistaril®, is a first-generation antihistamine used in horses to reduce itching and inflammation caused by environmental and insect allergens. Unlike newer antihistamines, it crosses the blood–brain barrier, which means it can also cause drowsiness...

Domperidone, sold under the trade name Equidone® Gel, is a medication used in horses to support hormone balance and digestive function. It works by blocking dopamine, a neurotransmitter that supresses certain hormones, including prolactin. In equine practice, domperidone is most commonly...

Dexamethasone is a widely used corticosteroid in equine medicine, valued for its anti-inflammatory and immunosuppressive properties. Dexamethasone works by dampening the body's inflammatory response, providing rapid relief of clinical signs and improving overall comfort and function. Because of its strength...

Diphenhydramine is an antihistamine commonly used in horses to manage allergic reactions, including hives, insect bite hypersensitivity, and other inflammatory skin conditions. While it is widely recognized under brand names like Benadryl®, its use in equine care is typically off-label...

Ketamine is a widely used medication in equine veterinary medicine, best known for its role as a fast-acting anesthetic. It is commonly administered during surgical procedures, diagnostic imaging, and emergency interventions, where it helps induce and maintain anesthesia while preserving...

Trimethoprim sulfadiazine, brand name Equisul-SDT®, is a combination antibiotic widely used in equine medicine for the treatment of bacterial infections. This medication combines two antimicrobial drugs that work together to stop bacteria from growing and multiplying, making it effective against...

Cetirizine, marketed in human medicine under the trade names Zyrtec® and Reactine®, is an antihistamine commonly used in human and small animal medicine. While there is interest in equine applications of antihistamine use, the effects of cetirizine in horses are...

Butylscopolamine, also Buscopan®, is a medication commonly used in horses to provide rapid relief from abdominal pain associated with spasmodic colic. As an antispasmodic agent, it works by relaxing smooth muscle in the gastrointestinal tract, helping reduce intestinal contractions that...

Cisapride is a prokinetic medication used in horses to stimulate movement in the gastrointestinal tract, helping restore normal gut motility when digestion slows or stops. It is most commonly used in cases of postoperative ileus, severe gastrointestinal hypomotility, or other...

Methocarbamol is a centrally acting muscle relaxant commonly used in horses to treat skeletal muscle spasms. These spasms can occur during conditions that cause muscle inflammation or injury and are often associated with disorders such as exertional rhabdomyolysis, commonly known...

Dantrolene is a skeletal muscle relaxant used in horses to manage conditions involving excessive skeletal muscle contraction or muscle damage, most notably exertional rhabdomyolysis (tying-up). Exertional rhabdomyolysis occurs when muscle cells become damaged during or after exercise, leading to pain,...

Clenbuterol is a bronchodilator used in horses for the management of lower airway disease, including equine asthma and other conditions associated with bronchoconstriction. These disorders occur when the small airways narrow due to inflammation, excess mucus, and smooth muscle contraction,...

Quinidine is an antiarrhythmic medication used in horses for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia that warrants medical intervention. Atrial fibrillation occurs when the upper chambers of the heart (the atria) beat in...

Autologous Protein Solution (APS) is a biologic therapy that has emerged as an innovative treatment for managing joint and soft tissue injuries in horses. This biologic therapy uses the horse's own blood to create a concentrated solution of anti-inflammatory proteins...

Equine inhalers are specialized devices used to deliver medication directly into a horse's lungs to help manage respiratory conditions. These devices are similar in design and function to inhalers used by humans, but they have been adapted to suit the...

Metronidazole (Flagyl®) is a commonly prescribed antibiotic in equine medicine, primarily used to treat bacterial infections in horses. It is particularly effective against clostridial infections, which can disrupt the delicate balance of gut bacteria and lead to severe gastrointestinal illness...

Hyaluronan injections, commonly known as hyaluronic acid (HA) injections, have become a trusted solution for managing joint health in horses. Whether your horse is dealing with osteoarthritis, recovering from an injury, or needs extra joint support as a performance horse,...

Stem cell therapy is gaining attention in equine veterinary care as a potential option for treating injuries and managing degenerative conditions. This treatment approach is being explored for its ability to support tissue repair and aid recovery in horses with...

Blood doping is a type of performance enhancement that artificially increases the blood’s oxygen carrying capacity. In equine sports, the purpose of blood doping is to improve a horse’s performance by raising the number of red blood cells (RBCs) in...

Antimicrobial resistance (AMR), also known as antibiotic resistance, is a growing global concern that extends beyond equine medicine into all aspects of human and animal health. The overuse and misuse of these critically important drugs can lead to the development...

Non-steroidal anti-inflammatory drugs (NSAIDs) are a type of medication used to reduce inflammation and treat pain in horses. In equine medicine, NSAIDs are commonly used in supportive care for a wide range of symptoms and conditions such as colic, pain,...

Equine sedation is a critical aspect of veterinary care, playing a vital role in ensuring the safety and well-being of both horses and handlers during various medical procedures. Horses are a large, powerful animal with a strong flight response, which...

Anesthesia refers to the loss of sensation and consciousness from administration of anesthetic medications. Anesthesia is a critical aspect of veterinary medicine, as it allows for life-saving or career-saving surgeries and diagnostic procedures that would otherwise be impossible to perform...

Non-steroidal anti-inflammatories, or NSAIDs, for short, are a type of medication commonly administered to horses for a variety of conditions. Veterinarians most often prescribe NSAIDs for soft tissue and musculoskeletal injuries, as well as for abdominal inflammation and pain. [ref...

Parasites are organisms that live in or on the horse, and rely on the horse for sustenance while often causing harm or disease. These include worms like roundworms, tapeworms, and bots, as well as external parasites such as ticks and...

Diagnostic analgesia, commonly referred to as a "nerve block," refers to numbing an area using an analgesic, such as lidocaine, for diagnostic purposes. Diagnostic analgesia is a crucial component of lameness examinations, as numbing certain areas of the horse's limbs...

Respiratory (lung) function is critical to ensure equine performance and overall health. Equine asthma, pneumonia, and lung capacity during exercise are all common health concerns for riders and trainers. One strategy to treat respiratory inflammation is delivering medication directly into...

Platelet-Rich Plasma (PRP) is a regenerative therapy used to treat horses with tendon and ligament injuries. PRP is a blood preparation where plasma, the water and protein component of blood containing no cells, is mixed with highly concentrated platelets and...