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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
“Steal phenomenon” proposed as the cause of blindness after arterial occlusion for treatment of guttural pouch mycosis in horses.
Journal of the American Veterinary Medical Association    October 1, 1990   Volume 197, Issue 7 811-812 
Freeman DE, Ross MW, Donawick WJ.No abstract available
Production of interleukin 2 and expression of interleukin 2 receptors by pony peripheral blood lymphocytes after stimulation with a soluble fraction of Trypanosoma evansi.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B    October 1, 1990   Volume 37, Issue 8 631-637 doi: 10.1111/j.1439-0450.1990.tb01107.x
Ahmed JS, Schmid G, Hörchner F.Pony peripheral blood lymphocytes (PBL) were stimulated with a soluble fraction of Trypanosoma (T.) evansi (SF). As determined by 3H-thymidine incorporation, the cells underwent a proliferative response and were able to: a) produce a factor having the biological activities of interleukin 2 (IL-2) since their supernatants could support the in vitro growth of pony PBL stimulated with concanavalin A (Con A-blasts); b) undergo a further proliferative response when incubated in short term cultures with SF, human recombinant IL-2 (hrIL-2), or both c) bind specifically radiolabelled hrIL-2 (125I-hrIL...
[Fructosamine as a valuable criterion for the evaluation of diabetic animals and its photometric determination].
Tierarztliche Praxis    October 1, 1990   Volume 18, Issue 5 441-446 
Staudacher G.The new photometrical kit fructosamine is tested for its use with canine, feline and equine blood. Normal values of fructosamine in nondiabetic animals as well as adequately and inadequately stabilized patients are given. The measurement of fructosamine is an excellent new tool for diagnosis and treatment of diabetes mellitus and should become an essential part of the control of the course of diabetes mellitus in animals.
Modulation of an adhesion-related surface antigen on equine neutrophils by bacterial lipopolysaccharide and antiinflammatory drugs.
Journal of leukocyte biology    October 1, 1990   Volume 48, Issue 4 306-315 doi: 10.1002/jlb.48.4.306
Bochsler PN, Slauson DO, Neilsen NR.The essential role of the CD11/CD18 family of leukocyte adhesion molecules (LeuCams) in neutrophil-substrate adhesion is well documented. We have found that a monoclonal antibody designated 60.3 (MoAb 60.3) that recognizes the common beta-subunit (CD18) on human neutrophils (PMN) also recognizes a surface antigen on equine PMN. Antigen expression as assessed by immunofluorescence flow cytometry was enhanced by zymosan-activated serum (ZAS) or phorbol 12-myristate 13-acetate (PMA) stimulation. Pretreatment of equine PMN with MoAb 60.3 inhibited ZAS-stimulated aggregation, indicating that the mo...
Identification using solid phase extraction and gas chromatography-mass spectrometry of timolol in equine urine after intravenous administration.
Journal of chromatography    September 28, 1990   Volume 518, Issue 1 215-220 doi: 10.1016/s0021-9673(01)93177-2
Duffield AM, Wise S, Keledjian J, Suann CJ.No abstract available
Isolation and partial structural characterization of an equine fibrinogen CNBr fragment that exhibits immunologic cross-reactivity with an A alpha-chain cross-linking region of human fibrinogen.
Biochemistry    September 25, 1990   Volume 29, Issue 38 8907-8916 doi: 10.1021/bi00490a005
Sobel JH, Thibodeau CA, Kolks MA, Canfield RE.Immunochemical studies of equine fibrinogen were conducted to characterize the structural basis for the immunologic cross-reactivity observed between human and equine A alpha chains when employing an antiserum to the 26K, human cyanogen bromide (CNBr) fragment, A alpha 241-476 (CNBr VIII). A 38K, equine CNBr fragment that reacts with this antiserum was isolated from CNBr-digested equine fibrinogen by Sephadex G-100 gel filtration. It was further purified by sequential hydrophobic chromatography on phenyl-Sepharose CL-4B, followed by reversed-phased (C-8) high-performance liquid chromatography ...
Side effects of indomethacin in ponies.
The Veterinary record    September 22, 1990   Volume 127, Issue 12 316 
Vandenbossche GM, Bouckaert S, De Muynck C, Remon JP.No abstract available
Surgical stapling for repair of a rectal tear in a horse.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 746-748 
Stewart RH, Robertson JT.A grade-4 rectal tear in a mare was successfully repaired per rectum, using a surgical stapling device. The mare had only minor postoperative complications. This technique has some advantages over previously described procedures, but should be reserved for use in selected cases.
Echocardiographic detection of an intact aneurysm in a horse.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 752-755 
Reef VB, Klumpp S, Maxson AD, Sweeney RW.Two-dimensional real-time echocardiographic examination of a 3-year-old Thoroughbred gelding with pleuropneumonia revealed an intact aneurysm of the right sinus of Valsalva, which was confirmed at postmortem examination. The horse had no clinical signs associated with the aneurysm.
Subcutaneous part of the masseteric ramus of the external carotid artery as a proposed site of pulse-taking in Thoroughbreds.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 751 
McCarthy PH.The subcutaneous part of the masseteric ramus of the external carotid artery can be used as a proposed site of pulse-taking in most Thoroughbreds. It is located on the lateral surface of the masseter muscle, and its contour may be visible in association with a summer coat.
Variable locations of nutrient foramina of the proximal phalanx in forelimbs of Thoroughbreds.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 736-738 
Kneller SK, Losonsky JM.Bilateral metacarpophalangeal radiographs of 100 Thoroughbreds were examined for visualization and location of the major nutrient foramen of the proximal phalanx. The foramina were located on the dorsal or palmar aspects of the cortex or were not visible radiographically. Of the 100 horses, 60 had the same pattern in both forefeet. In the remaining 40 horses, the left and right proximal phalangeal foramina were asymmetric. Of the 200 proximal phalangeal foramina (100 horses), 53 were on the dorsal aspect of the cortex and 101 were on the palmar aspect of the cortex; 46 were not visible radiogr...
Prekallikrein deficiency in a family of Belgian horses.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 741-745 
Geor RJ, Jackson ML, Lewis KD, Fretz PB.A 7-year-old Belgian stallion hemorrhaged excessively after castration; the hemostatic mechanism was investigated. The horse had normal one-stage prothrombin time and markedly prolonged activated partial thromboplastin time (APTT). Results of intrinsic coagulation factor assays were all normal with the exception of prekallikrein activity, which was markedly reduced (less than 1% activity; value for control population, 63 to 150%). Two of this horse's full siblings, a brother and sister, had markedly prolonged APTT and low prekallikrein values (2.5% and less than 1%, respectively). The addition...
Vacuum phenomenon in the metatarsophalangeal joint of a horse.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 749-750 
Specht TE, Poulos PW, Metcalf MR, Robertson ID.Vacuum phenomenon was induced inadvertently during radiographic examination of a metatarsophalangeal joint of a lame horse. The phenomenon was recreated in a sound horse when a metacarpophalangeal joint was radiographed in a stress-flexed position. Distraction of apposing articular surfaces may induce the vacuum phenomenon, which could result in misdiagnosis of an osteochondral defect or fracture.
Malignant melanoma in the foot of a horse.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 756-758 
Honnas CM, Liskey CC, Meagher DM, Brown D, Luck EE.A 24-year-old horse had a malignant melanoma of the right forefoot. Because surgical excision of the melanoma was incomplete, as determined by histologic examination of the excised tissue margins, the tumor margins were injected with a matrix therapeutic implant containing cis-diamminedichloroplatinum, epinephrine, and purified bovine collagen matrix. The foot healed and the horse remained clinically free of disease for 26 months before recurrence of malignant melanoma. Surgical exploration of the digit revealed extensive involvement of the foot, and the horse was euthanatized.
What is your diagnosis? Hoof abscesses and cellulitis extending along the palmar aspect of the pastern of the left forelimb.
Journal of the American Veterinary Medical Association    September 15, 1990   Volume 197, Issue 6 769-770 
Leonard JM, Anderson K.No abstract available
Safety of horseriding.
BMJ (Clinical research ed.)    September 8, 1990   Volume 301, Issue 6750 496 doi: 10.1136/bmj.301.6750.496-b
Nicholl JP.No abstract available
Crystallization of a calcium-binding lysozyme from horse milk.
The Journal of biological chemistry    September 5, 1990   Volume 265, Issue 25 14886-14887 
Zeng J, Rao KR, Brew K, Fenna R.Crystals of the calcium-containing lysozyme from horse milk have been grown by precipitation with sodium phosphate. The crystals are orthorhombic space group P2(1)2(1)2(1) with cell dimensions a = 53.2, b = 57.1, and c = 38.2 A and contain a single molecule in the asymmetric unit. The crystals are suitable for high resolution x-ray structural analysis.
Ultrastructural findings in horses with chronic obstructive pulmonary disease (COPD). II: Pathomorphological changes of the terminal airways and the alveolar region.
Equine veterinary journal    September 1, 1990   Volume 22, Issue 5 349-355 doi: 10.1111/j.2042-3306.1990.tb04288.x
Kaup FJ, Drommer W, Damsch S, Deegen E.Extensive light and electron microscope studies (transmission and scanning electron microscopy) of the bronchioles and alveolar region, in 28 horses suffering chronic obstructive pulmonary disease (COPD) and eight control horses, revealed good correlation between clinical severity and morphological changes. In the bronchiolar epithelium the non-ciliated bronchiolar epithelial (Clara) cells, in particular, showed ultrastructural alterations and, even in the mild stages of disease, these presented degenerative changes and lack of differentiation. Together with loss of granulation in the Clara ce...
Effect of acute acidemia on blood biochemical variables in healthy ponies.
American journal of veterinary research    September 1, 1990   Volume 51, Issue 9 1375-1379 
Gossett KA, French DD, Cleghorn B, Church GE.L-Lactic acid and D,L-lactic acid infusion in ponies resulted in metabolic acidosis with high anion gap (AG). Increased AG was explained entirely by increased blood L- and D-lactate concentrations. Hydrochloric acid infusion caused metabolic acidosis with decreased AG. Saline (NaCl) infusion caused mild metabolic acidosis, with no significant change in AG. Plasma K+ concentration was decreased by all types of infusions, with a maximum of 0.50, 0.25, 0.40, 0.50 mmol/L below baseline at the end of infusion in the L-lactic acid-, D,L-lactic acid-, HCl-, and NaCl-infused ponies, respectively. Only...
Intraocular melanomata in the horse.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 76-82 doi: 10.1111/j.2042-3306.1990.tb04718.x
Barnett KC, Platt H.No abstract available
A comparison of two computer-automated semen analysis instruments for the evaluation of sperm motion characteristics in the stallion.
Journal of andrology    September 1, 1990   Volume 11, Issue 5 453-459 
Jasko DJ, Lein DH, Foote RH.Two commercially available computer-automate semen analysis instruments (CellSoft Automated Semen Analyzer and HTM-2000 Motion Analyzer) were compared for their ability to report similar results based on the analysis of pre-recorded video tapes of extended, motile stallion semen. The determinations of the percentage of motile cells by these instruments were more similar than the comparisons between subjective estimates and either instrument. However, mean values obtained from the same sample may still differ by as much as 30 percentage units between instruments. Instruments varied with regard ...
Use of the forced oscillating airflow technique to measure the resistance of the equine upper airway: effects of laryngoventriculectomy and laryngoplasty.
Research in veterinary science    September 1, 1990   Volume 49, Issue 2 229-235 
Hall LW, Young SS, Franklin RJ, Jefferies AK, Corke MJ.Investigations were carried out to determine whether measurements of total respiratory resistance (TRR) made in resting animals could detect changes due to laryngeal hemiplegia. Control values of TRR were obtained in eight ponies and in six of these the measurements were repeated after division of the left recurrent laryngeal nerve in the mid-cervical region; two were retained as controls. A further set of measurements were made before two of the operated animals were subjected to left laryngoventriculectomy (Hobday operation). A laryngoplasty ('tie-back' operation) was performed on another tw...
Changes in coagulation and fibrinolysis in horses during exercise.
American journal of veterinary research    September 1, 1990   Volume 51, Issue 9 1335-1339 
McKeever KH, Hinchcliff KW, Kociba GJ, Reed SM, Muir WW.Changes in clotting time (CT) and fibrinolytic activity (FA) were evaluated in 6 mature, female horses during exercise. Two trials were performed on consecutive days, using a randomized crossover design. Each mare was assigned to either an exercise trial or a control trial on the first day, and to the alternate trial 24 hours later. Mares exercised for 20 minutes on a treadmill at an elevation of 2 degrees and a velocity of 5 m/s. Venous blood samples were collected immediately before exercise, at 4, 8, 12, 16 and 20 minutes during exercise, and 15 minutes after cessation of exercise. Blood wa...
Aniridia in a thoroughbred horse.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 29 doi: 10.1111/j.2042-3306.1990.tb04707.x
Ueda Y.No abstract available
The equine fundus. II: Normal anatomical variants and colobomata.
Equine veterinary journal. Supplement    September 1, 1990   Issue 10 50-54 doi: 10.1111/j.2042-3306.1990.tb04712.x
Matthews AG, Crispin SM, Parker J.A wide range of fundic variants are encountered during routine ophthalmoscopic examination of visually normal horses, often causing the examiner difficulty in assessing their clinical significance. Many of these are anatomical variants having no significant effect on visual function, and lie within the limits of normality in the horse. This paper illustrates this range of variants and discusses their anatomical basis and physiological consequences. Colobomata are non-progressive discontinuities in the structure of the anatomic fundus, occasionally noted as incidental findings during ophthalmos...
Comparison of the adrenocortical response to both pharmacological and physiological stresses in sport horses.
Zentralblatt fur Veterinarmedizin. Reihe A    September 1, 1990   Volume 37, Issue 8 601-604 
Linden A, Art T, Amory H, Desmecht D, Lekeux P.Seven sport horses were investigated to compare physiological and pharmacological stresses on the plasma glucocorticosteroid levels. Venous blood was sampled and analysed for cortisol concentrations before and after each type of stress. The physiological stress was induced by the completion of a cross-country and the pharmacological one, by an intravenous ACTH administration (200 micrograms) in the same horses, one week after the course. Both exercise and ACTH injection induced a highly significant cortisol increase of 79 +/- 0.10% and 160 +/- 0.18%, respectively. The relative plasma cortisol ...
Alteration of intestinal enzyme activities associated with extensive large-colon resection in horses.
American journal of veterinary research    September 1, 1990   Volume 51, Issue 9 1329-1334 
Bertone AL, Toofanian F, Stashak TS.Lactase, maltase, sucrase, and alkaline phosphatase activities were determined in the intestinal mucosa from 3 locations in the small intestine and 4 locations in the large intestine 1 year after extensive large-colon resection (group 1; n = 5) and 1 year after sham operation (group 2; n = 3) in horses. Lactase, maltase, and sucrase activities were similar (P greater than 0.05) between group-1 and group-2 horses in all locations measured in the intestinal tract. Alkaline phosphatase activity in the remaining large colon of group-1 horses was significantly (P less than 0.05) greater than the ac...
Applications of skin grafting in large animals.
Problems in veterinary medicine    September 1, 1990   Volume 2, Issue 3 442-462 
Wilson DG.Injuries involving full-thickness skin wounds are common in large animals. Skin grafting can shorten the healing time and improve the cosmetic result. Techniques that have been used successfully in the management of full-thickness skin wounds include full-thickness skin grafts, split-thickness skin grafts, tunnel grafts, pinch/punch grafts, and immediate split-thickness skin grafts. The technical aspects of each of these procedures are detailed and representative cases are presented.
Metabolic and hormonal changes associated with arthroscopic surgery in the horse.
Equine veterinary journal    September 1, 1990   Volume 22, Issue 5 313-316 doi: 10.1111/j.2042-3306.1990.tb04279.x
Robertson SA, Steele CJ, Chen CL.The effect of general anaesthesia and arthroscopic surgery on blood glucose and lactate, plasma non-esterified fatty acids, insulin, beta-endorphin and cortisol was investigated in seven horses. Animals were premedicated with xylazine and anaesthesia was induced with guaifenesin and sodium thiamylal and maintained with halothane vaporised in oxygen. Blood samples were collected in the pre-, intra- and post operative period. Induction of anaesthesia was associated with a transient hyperglycaemia and a significant rise in plasma insulin levels. Plasma insulin values fell during surgery but showe...
Equine euthanasia.
Journal of the American Veterinary Medical Association    September 1, 1990   Volume 197, Issue 5 555-556 
No abstract available