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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Attenuation of the virulence of a recombinant influenza virus expressing the naturally truncated NS gene from an H3N8 equine influenza virus in mice.
Veterinary research    November 15, 2016   Volume 47, Issue 1 115 doi: 10.1186/s13567-016-0400-7
Na W, Lyoo KS, Yoon SW, Yeom M, Kang B, Moon H, Kim HK, Jeong DG, Kim JK, Song D.Equine influenza virus (EIV) causes a highly contagious disease in horses and other equids. Recently, we isolated an H3N8 EIV (A/equine/Kyonggi/SA1/2011) from a domestic horse in South Korea that exhibited symptoms of respiratory disease, and found that the EIV strain contained a naturally mutated NS gene segment encoding a truncated NS1 protein. In order to determine whether there was an association between the NS gene truncation and viral virulence, a reverse genetics system was applied to generate various NS gene recombinant viruses using the backbone of the H1N1 A/Puerto Rico/8/1934 (PR/8)...
Replication of neurovirulent equine herpesvirus type 1 (EHV-1) in CD172a+ monocytic cells.
Comparative immunology, microbiology and infectious diseases    November 15, 2016   Volume 50 58-62 doi: 10.1016/j.cimid.2016.11.006
Laval K, Van Cleemput J, Poelaert KC, Brown IK, Nauwynck HJ.Equine herpesvirus type 1 (EHV-1) is responsible for respiratory disorders, abortion and myeloencephalopathy (EHM) in horses. Two pathotypes of EHV-1 strains are circulating in the field: neurovirulent (N) and non-neurovirulent (NN). For both strains, CD172a monocytic cells are one of the main carrier cells of EHV-1 during primary infection, allowing the virus to invade the horse's body. Recently, we showed that EHV-1 NN strains showed a restricted and delayed replication in CD172a cells. Here we characterize the in vitro replication kinetics of two EHV-1N strains in CD172a cells and investiga...
Urinary effects of xylazine and general anesthesia in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 107 doi: 10.1046/j.1467-2995.2002.00078_25.x
Watson ZE, Steffey EP, Van Hoogmoed LM, Snyder JR.No abstract available
The effects of ephedrine on intramuscular blood flow and other cardiopulmonary parameters in halothane-anesthetized ponies.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 4 171-181 doi: 10.1046/j.1467-2995.2002.00095.x
Lee YL, Clarke KW, Alibhai HI, Song DY.To evaluate the effect of ephedrine on intramuscular blood flow and hemodynamic parameters during equine anesthesia. Methods: Prospective experimental study. Methods: Six healthy adult Welsh Mountain ponies (five males, one female, mean weight: 267 kg, range: 213-347 kg). Methods: Halothane-anesthetized ponies received an IV bolus of ephedrine (0.1 mg kg), followed 30 minutes later by a second IV ephedrine injection (0.2 mg kg). Changes in intramuscular blood flows (IMBF) in upper and lower triceps brachii were measured by laser Doppler flowmetry. Cardiopulmonary measurements were made at inte...
β-endorphin immunoreactivity during anaesthesia in equidae.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 27, Issue 1 27-35 doi: 10.1046/j.1467-2995.2000.00004.x
Taylor PM, Luna S, Dye A.To determine the effects of surgery, hypoxia, hypercapnia and flunixin administration on plasma β-endorphin immunoreactivity (BEI) in anaesthetized horses. Methods: Prospective crossover study. Methods: Six healthy adult Welsh Mountain ponies and seven healthy adult Thoroughbreds. Methods: Ponies were anaesthetized with thiopentone and halothane or with pentobarbitone and the horses with guaiphenesin, thiopentone and halothane. Ponies were anaesthetized for 2 hours and on separate occasions underwent a period of hypoxia, hypercapnia, anaesthesia only, or were given flunixin at induction. The ...
Aerosolized salbutamol (albuterol) improves PaO2 in hypoxaemic anaesthetized horses – a prospective clinical trial in 81 horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 4 212-218 doi: 10.1046/j.1467-2995.2002.00100.x
Robertson SA, Bailey JE.To compare the arterial pH and blood gas values, heart rate and mean arterial blood pressure, in hypoxaemic anaesthetized horses, before and after treatment, with a salbutamol (albuterol) aerosol. Methods: Eighty-one client-owned horses weighing between 114 and 925 kg. Fifty-seven underwent emergency abdominal surgery and 24 were anaesthetized for elective procedures. Methods: Pre-anaesthetic medication included xylazine, detomidine, butorphanol and morphine, alone or in various combinations. Induction of anaesthesia was achieved with guaifenesin and ketamine, diazepam and ketamine, or guaifen...
A comparison of anesthetic risk factors and outcomes in light and draft horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 30, Issue 2 113-114 doi: 10.1046/j.1467-2995.2003.00133_32.x
Riley CB, Riedesel DH, Dohoo IR, Hatfield CL, Clinch S.No abstract available
Airlifting horses by helicopter: sedation requirements.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 108-109 doi: 10.1046/j.1467-2995.2002.00078_28.x
Pettifer G, Smith J, McConnico R, Latimer F, Hubert J.No abstract available
Evaluation of xylazine, butorphanol and propofol for short-term intravenous anesthesia in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 106 doi: 10.1046/j.1467-2995.2002.00078_22.x
Garcia Lascurain AA, Sumano Lopez H, Steffey EP, Santillan Doherty P, Nuñez Hernandez E.No abstract available
The pre-emptive effect of epidural ketamine on wound sensitivity in horses tested by using von Frey filaments.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 4 200-206 doi: 10.1046/j.1467-2995.2002.00083.x
Rédua MA, Valadão CA, Duque JC, Balestrero LT.To evaluate the pre-emptive analgesic effect of pre-incisional epidural ketamine. Methods: A blinded, randomized experimental study. Methods: Sixteen mixed breed mares, 7.6 ± 2.8 years old, weighing 352 ± 32 kg. Methods: In a pilot study, an incision was made on one lateral thigh using a lidocaine block and no further analgesics, and it was verified that the nociceptive threshold was lower on the incised side than nonincised side (p ≤ 0.05), and that von Frey filaments evoked a pain response. The 16 animals were divided into group A (ketamine, n = 9) and B (saline, n = 7). An epidural cath...
Changes in the EEG in horses during surgery: the effect of an intravenous infusion of alfentanil.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 90 doi: 10.1046/j.1467-2995.2002.00701.x
Murrell JC, White KL, Johnson CB, Taylor PM, Waterman-Pearson AE.No abstract available
Quantification of dose-dependent respiratory depression in isoflurane-anesthetized horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 104 doi: 10.1046/j.1467-2995.2002.00078_17.x
Brosnan RJ, Imai A, Steffey EP.No abstract available
Detomidine reduces isoflurane anesthetic requirement (MAC) in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 4 223-227 doi: 10.1046/j.1467-2995.2002.00107.x
Steffey EP, Pascoe PJ.To quantitate the dose- and time-related magnitude of the anesthetic sparing effect of, and selected physiological responses to detomidine during isoflurane anesthesia in horses. Methods: Randomized cross-over study. Methods: Three, healthy, young adult horses weighing 485 ± 14 kg. Methods: Horses were anesthetized on two occasions to determine the minimum alveolar concentration (MAC) of isoflurane in O and then to measure the anesthetic sparing effect (time-related MAC reduction) following IV detomidine (0.03 and 0.06 mg kg). Selected common measures of cardiopulmonary function, blood glucos...
Effect of an inhaled β-2 adrenergic receptor agonist on arterial partial pressure of oxygen in hypoxemic anesthetized horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 28, Issue 2 106 doi: 10.1111/j.1467-2987.2001.40-21.x
Bailey J, Robertson S, Pablo L, Cantwell S, Davis W.No abstract available
Anaesthesia in horses using halothane and intravenous ketamine-guaiphenesin: a clinical study.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 1 20-28 doi: 10.1046/j.1467-2987.2001.00060.x
Spadavecchia C, Stucki F, Moens Y, Schatzmann U.The aim of this study was to define and evaluate a combined inhalation-intravenous anaesthetic protocol for use in equine anaesthesia. Methods: Prospective, randomized clinical trial. Methods: Twenty-eight horses (body mass 522 ± 82; 330-700 kg [mean ± SD; range]) with a mean age of 6 ± 4 years (range: 2-18 years) presented to the university hospital for various surgical procedures requiring general anaesthesia. Methods: Animals were randomly allocated to one of two treatment groups. Anaesthesia was maintained in 14 horses with halothane alone (H group). The mean end-tidal halothane concent...
A laboratory study of horses recovering from desflurane and isoflurane anaesthesia.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 90-91 doi: 10.1046/j.1467-2995.2002.00702.x
Steffey EP, Brosnan RA, Imai A, Mama KR.No abstract available
Ketamine-guaiphenesin infusion to supplement halothane anaesthesia in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 27, Issue 1 54-55 doi: 10.1046/j.1467-2995.2000.00008-1.x
Spadavecchia C, Stucki F, Schatzmann U.No abstract available
Seroprevalence of West Nile virus antibodies in equids in the North-East of Algeria and detection of virus circulation in 2014.
Comparative immunology, microbiology and infectious diseases    November 15, 2016   Volume 50 8-12 doi: 10.1016/j.cimid.2016.11.005
West Nile fever (WNF) is a viral disease of wild birds transmitted by mosquitoes. Humans and equids can also be affected and suffer from meningoencephalitis. In Algeria, since the 1994 epidemic, no data on WNV circulation was available until 2012. In September 2012, a fatal human case of WNV neuro-invasive infection occurred in Jijel province. This study describes the first seroprevalence study of West Nile virus (WNV) antibodies conducted in the equine population in Algeria. During 2014, serum samples were collected from 293 equids (222 donkeys and 71 horses) asymptomatic and unvaccinated for...
Retrospective analysis of detomidine infusion for standing chemical restraint in 51 horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 1 54-57 doi: 10.1046/j.1467-2987.2001.00047.x
Wilson DV, Bohart GV, Evans AT, Robertson S, Rondenay Y.To assess the effectiveness of a detomidine infusion technique to provide standing chemical restraint in the horse. Methods: Retrospective study. Methods: Fifty-one adult horses aged 9.5 ± 6.9 years (range 1-23 years) and weighing 575 ± 290.3 kg. Methods: Records of horses presented to our clinic over a 3-year period in which a detomidine infusion was used to provide standing chemical restraint were reviewed. Information relating to the types of procedure performed, duration of infusion, drug dosages and adjunct drugs administered was retrieved. Results: Detomidine was administered as an ini...
Cardiopulmonary effects associated with head-down position in halothane-anesthetized ponies with or without capnoperitoneum.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 76-89 doi: 10.1046/j.1467-2995.2002.00077.x
Duke T, Cruz AM, Cruz JI, Howden KJ.To compare the cardiopulmonary effects of the head-down position, with or without capnoperitoneum, in halothane-anesthetized horses. Methods: Prospective randomized study. Methods: Five ponies (four mares, one stallion; bodyweight 302 ± 38.4 kg [mean ± SD]) were used. Methods: The ponies were anesthetized with xylazine, guiafenesin, ketamine, and maintained with halothane/oxygen and lungs were ventilated to 40 ± 2 mm Hg (5.3 ± 0.3 kPa) end-tidal CO tension. After baseline cardiopulmonary measurements, ponies were kept in horizontal position for 30 minutes, then tilted head-down 30° to the...
Comparison of romifidine-ketamine-midazolam and romifidine-tiletamine-zolazepam total intravenous anaesthesia (TIVA) for clinical anaesthesia in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 92-93 doi: 10.1046/j.1467-2995.2002.00705.x
Bouts T, Gasthuys F, Vlaminck L, Van Branteghem L.No abstract available
Influence of sevoflurane and desflurane anaesthesia on blood biochemical values in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 27, Issue 1 55-56 doi: 10.1046/j.1467-2995.2000.00008-3.x
Steffey EP, Galey F, Mama KR, Puschner B.No abstract available
Nitric oxide production in normal, endotoxemic and critically ill colic horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 28, Issue 2 105 doi: 10.1046/j.1467-2987.2001.temp.doc.x-i11
Jones JL, Doherty TJ, Rohrbach BW.Total serum nitrate/nitrite concentration (SNN in µM L−1), an indirect measure of nitric oxide (NO), has been reported to be increased during critical illness in people and dogs. The relationship of NO to critical illness in horses is unknown. The purpose of this study was to quantify and compare SNN in normal, endotoxin treated, and horses with naturally acquired colic requiring surgical intervention.
A Microbiological Map of the Healthy Equine Gastrointestinal Tract.
PloS one    November 15, 2016   Volume 11, Issue 11 e0166523 doi: 10.1371/journal.pone.0166523
Ericsson AC, Johnson PJ, Lopes MA, Perry SC, Lanter HR.Horses are exquisitely sensitive to non-specific gastrointestinal disturbances as well as systemic and extraintestinal conditions related to gut health, yet minimal data are available regarding the composition of the microbiota present in the equine stomach, small intestine, and cecum and their relation to fecal microbiota. Moreover, there is minimal information regarding the concordance of the luminal and mucosal microbial communities throughout the equine gut. Illumina-based 16S rRNA gene amplicon sequencing of the luminal and mucosal microbiota present in seven regions of the gastrointestin...
Evaluation of anesthesia maintained with halothane and epidural xylazine for hind limb surgery in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 28, Issue 2 107 doi: 10.1046/j.1467-2987.2001.temp.doc.x-i17
Teixeira Neto FJ, McDonell W, Pearce S, Kerr C, Hurtig M, Durongphongtorn S.No abstract available
Effects of guaiphenesin on the equine electroencephalogram during anaesthesia with halothane in oxygen.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 27, Issue 1 6-12 doi: 10.1046/j.1467-2995.2000.00011.x
Johnson CB, Bloomfield M, Taylor PM.To identify and characterize the effects of guaiphenesin (GGE) on the electroencephalogram during halothane anaesthesia. Methods: Prospective controlled study. Methods: Eight healthy Welsh mountain pony geldings between 5 and 9 years old and weighing between 270 and 330 kg (mean 301 kg). Methods: Anaesthesia was induced with thiopentone and maintained using halothane in oxygen. End tidal halothane was maintained above 0.75 and below 0.85%. The EEG was recorded continuously and a binaural broad band click stimulus was provided throughout the experiment at 6.1224 Hz. An infusion of 1500 mg GGE w...
The effects of ventilation on intercranial and cerebral perfusion pressures in isoflurane-anaesthetized horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 91-92 doi: 10.1046/j.1467-2995.2002.00704.x
Brosnan RJ, Steffey EP, LeCouteur RA, Imai A, Kortz GD.No abstract available
Blood pressure and electrocardiographic effects of acepromazine in anaesthetized horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 30, Issue 2 94-95 doi: 10.1046/j.1467-2995.2003.00132_11.x
Murison PJ, Clutton RE, Blissitt KJ, Funnell OD.No abstract available
Clinical responses and plasma drug concentrations associated with different infusions of xylazine and ketamine in horses.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 27, Issue 1 58-59 doi: 10.1046/j.1467-2995.2000.00008-9.x
Mama KR, Wagner AE, Steffey EP, Kollias-Baker C, Hellyer PW, Golden AE, Brevard LF.No abstract available
Effect of xylazine and detomidine on urine production in horses deprived of food and water.
Veterinary anaesthesia and analgesia    November 15, 2016   Volume 29, Issue 2 107 doi: 10.1046/j.1467-2995.2002.00078_24.x
Nuñez Hernandez E, Steffey EP, Ocampo Camberos L, Rodriguez Monterde A, Garcia Lascurain AA.No abstract available