Analyze Diet

Topic:Prevention

Prevention in horses encompasses strategies and measures aimed at reducing the risk of disease, injury, and other health-related issues. It involves a combination of management practices, vaccination protocols, nutrition, and regular veterinary care to maintain optimal health and performance. Preventive measures may include routine health screenings, parasite control, dental care, and environmental management to minimize stress and exposure to pathogens. This page compiles peer-reviewed research studies and scholarly articles that explore various preventive approaches, their implementation, and their impact on equine health and welfare.
Differences in bone turnover markers and injury risks between local and international horses: A Victorian Spring Racing Carnival study.
Equine veterinary journal    April 18, 2024   Volume 57, Issue 2 333-346 doi: 10.1111/evj.14098
Ayodele BA, Pagel CN, Mackie EJ, Armour F, Yamada S, Zahra P, Courtman N, Whitton RC, Hitchens PL.Musculoskeletal injuries (MSI) are common in racehorses and have been of increasing concern in horses travelling internationally to compete. Understanding the differences in bone turnover between local horses and international horses following long-distance air transportation may inform MSI prevention strategies. Objective: To understand the differences in bone turnover markers and risk of MSI between local horses and international horses following long-distance air transportation. Methods: Prospective cohort. Methods: The concentrations of bone turnover markers (OCN and CTXI), markers of stre...
Effects of tamoxifen on the immune response phenotype in equine peripheral blood mononuclear cells.
Frontiers in veterinary science    April 10, 2024   Volume 11 1381162 doi: 10.3389/fvets.2024.1381162
Rodríguez M, Quiroga J, Cortés B, Morán G, Henríquez C.Tamoxifen (TAM) is widely utilized in the prevention and treatment of human breast cancer and has demonstrated the potential to modulate the immune response. It has been proposed as a therapeutic tool for immune-mediated diseases. TAM has been investigated as a possible treatment for asthma-like conditions in horses, revealing specific impacts on the innate immune system. While the effects of TAM on equine neutrophils are well-documented, its influence on lymphocytes and the modulation of the immune response polarization remains unclear. This study employed peripheral blood mononuclear cells ...
Injury prevention in Thoroughbred racehorses.
Equine veterinary journal    April 5, 2024   Volume 56, Issue 3 386-388 doi: 10.1111/evj.14077
Muir P, Whitton RC.No abstract available
Immunoproteomics enable broad identification of new Aspergillus fumigatus antigens in severe equine asthma.
Frontiers in immunology    February 29, 2024   Volume 15 1347164 doi: 10.3389/fimmu.2024.1347164
Jentsch MC, Lübke S, Schrödl W, Volke D, Krizsan A, Hoffmann R, Kaiser-Thom S, Gerber V, Marti E, Wagner B, Schnabel CL.Severe equine asthma (SEA) is a common chronic disease of adult horses with characteristic recurrent airway obstruction and similarities to neutrophilic asthma in humans. As an extrinsic stimulus, hay dust exposure is a major risk factor and induces acute exacerbation in susceptible horses. However, single inducing agents of SEA have hardly been identified on a molecular basis. () is a common mold species in hay and has been described as a major provoking agent of SEA. Unassigned: Aiming to identify disease-relevant antigens, we analyzed using an immunoproteomics approach on two-dimensional ...
The effects of food on the pharmacokinetics of mycophenolate mofetil in healthy horses.
Journal of veterinary pharmacology and therapeutics    February 9, 2024   doi: 10.1111/jvp.13430
Bello K, Lorch G, Papich MG, Kim K, Toribio RE, Yan L, Xie Z, Hill K, Phelps MA.Additional immunomodulatory treatment is needed for the management of immune-mediated disease in horses. Mycophenolate mofetil (MMF) is an immunomodulatory agent used in human and veterinary medicine for the prevention of graft rejection and the management of autoimmune diseases. Few studies exist investigating the pharmacokinetics of MMF in horses. The aim of this study was to evaluate the pharmacokinetics of a single dose of MMF in healthy horses in the fed vs. fasted state. Six healthy Standardbred mares were administered MMF 10 mg/kg by a nasogastric (NG) tube in a fed and fasted state. ...
Experiences of Interdisciplinary Working from the Perspective of the Society of Master Saddlers Qualified Saddle Fitters.
Animals : an open access journal from MDPI    February 7, 2024   Volume 14, Issue 4 559 doi: 10.3390/ani14040559
Nankervis K, MacKechnie-Guire R, Maddock C, Pyatt A.Horse owners seek the advice and support of a number of equestrian professionals in carrying out their duty of care for their animal. In some instances, these professionals form a multi-disciplinary team (MDT). The aim of this study was to explore the experiences of the Society of Master Saddlers' qualified saddle fitters (SMSQSFs) working with other professionals and to understand the nature of inter-disciplinary working from an SMSQSF perspective. Semi-structured, one-to-one online interviews with fourteen SMSQSFs were completed. Areas explored included the nature of the participant's client...
Prevalence and risk factors for epizootic lymphangitis among equids in ethiopia during 2002-2023: A systematic review and meta-analysis.
Journal of equine veterinary science    February 4, 2024   Volume 134 105012 doi: 10.1016/j.jevs.2024.105012
Girma A, Tamir D.In Sub-Saharan Africa (SSA), particularly in Ethiopia, Epizootic Lymphangitis (EL) is the most prevalent fungal disease of equids, which causes significant economic losses as well as a decrease in equid populations. Therefore, this systematic review and meta-analysis were designed to pool the results of individual studies and estimate the prevalence of EL among equids in Ethiopia. A systematic search of research articles on the prevalence and risk factors of EL among equids in Ethiopia was conducted in registers, databases, and other sources. Cochrane's Q, inverse variance (I2), sensitivity an...
The effect of feeding a commercial feedstuff on gastric squamous gastric disease (ESGD) healing and prevention of recurrence.
Journal of equine veterinary science    January 27, 2024   Volume 133 105015 doi: 10.1016/j.jevs.2024.105015
Menzies-Gow NJ, Shurlock T.Feedstuffs are often recommended to mitigate potential damage from acid associated with equine squamous gastric disease (ESGD). In acidic conditions, pectin alters its structure to one like mucus and binds the stomach mucosa, whilst alfalfa has a strong intrinsic acid buffering capacity. The study aimed to determine whether feeding a commercial beet pulp/alfalfa/oat fibre mix aids ESGD healing and/or prevention of recurrence. Ten adult horses with naturally occurring ESGD were included. All animals were treated with omeprazole as per the attending veterinarian's recommendation and randomly all...
Prospective, longitudinal assessment of subchondral bone morphology and pathology using standing, cone-beam computed tomography in fetlock joints of 2-year-old Thoroughbred racehorses in their first year of training.
Equine veterinary journal    January 21, 2024   doi: 10.1111/evj.14048
Ciamillo SA, Wulster KB, Gassert TM, Richardson DW, Brown KA, Stefanovski D, Ortved KF.Catastrophic injuries of the fetlock joints occur in Thoroughbred racehorses and are preceded by stress-induced bone injury. Early detection of subchondral bone injury is essential to prevent irreversible damage or bone failure. Objective: To investigate the use of standing, robotic cone-beam computed tomography (CBCT) for assessing longitudinal changes in subchondral bone morphology and pathology of the fetlock joints associated with race training in young Thoroughbreds. Methods: Observational cohort study. Methods: Forty-one 2-year-old Thoroughbred racehorses were recruited prior to the star...
Isolation of lactic acid bacteria from the reproductive tract of mares as potentially beneficial strains to prevent equine endometritis.
Veterinary research communications    January 18, 2024   Volume 48, Issue 3 1353-1366 doi: 10.1007/s11259-024-10295-2
Silva JA, Castañares M, Mouguelar H, Valenciano JA, Pellegrino MS.Endometritis, the inflammation of the endometrium, is the leading cause of subfertility in mares, and therefore responsible for major economic losses in the horse industry worldwide. It is generally treated with uterine lavages combined with ecbolic agents and local or systemic antibiotics. However, since antibiotic overuse has been associated with antimicrobial resistance in mares with persistent endometritis, new prevention and treatment alternatives are needed. One such alternative could be the use of probiotic lactic acid bacteria (LAB) isolated from the host. Thanks to their species speci...
Genome-wide association study suggests genetic candidate loci of insulin dysregulation in Finnhorses.
Veterinary journal (London, England : 1997)    January 15, 2024   Volume 303 106063 doi: 10.1016/j.tvjl.2024.106063
Weckman MJ, Karikoski NP, Raekallio MR, Box JR, Kvist L.Equine metabolic syndrome (EMS) is a common welfare problem in horses worldwide. It is characterized by insulin dysregulation (ID), predisposition to laminitis and often obesity. EMS is multifactorial by nature, with both the environment and genetics contributing to the phenotype. Environmental factors, such as feeding and exercise, can be controlled, thus forming the basis for treatment and prevention. Genetic factors, by contrast, are less well-known and not easily controllable. The aim of this study was to identify potential genetic loci influencing ID/EMS in Finnhorses. A single-breed (Fin...
Survey on sanitary practices and knowledge about infectious diseases among equine owners in the State of Rio Grande do Norte, Brazil.
Brazilian journal of veterinary medicine    November 27, 2023   Volume 45 e003323 doi: 10.29374/2527-2179.bjvm003323
Medeiros PR, Figueiredo LS, de Melo UP, Mariz ALB, de Brito EL, Araújo IRDS, Silva ALDC, Costa MHDS, Ferreira C, Assis DB, da Silva CRM, de Souza AL....As the primary decision-maker about the health, nutrition, and well-being of their horses, owners' knowledge of correct management practices and clinical changes can potentially affect the immediate health of their horses, in addition to having an impact on the prevention of disease spread in the herd. The adoption of management practices to prevent the introduction and spread of pathogens depends on various factors, including demographics, awareness of the problem, perceived responsibility, previously held beliefs, and sociocultural norms. This study aimed to evaluate the health management pr...
Vaccination for the prevention of equine herpesvirus-1 disease in domesticated horses: A systematic review and meta-analysis.
Journal of veterinary internal medicine    November 6, 2023   Volume 38, Issue 3 1858-1871 doi: 10.1111/jvim.16895
Osterrieder K, Dorman DC, Burgess BA, Goehring LS, Gross P, Neinast C, Pusterla N, Hussey GS, Lunn DP.Equine herpes virus type 1 (EHV-1) infection in horses is associated with respiratory and neurologic disease, abortion, and neonatal death. Objective: Vaccines decrease the occurrence of clinical disease in EHV-1-infected horses. Methods: A systematic review was performed searching multiple databases to identify relevant studies. Selection criteria were original peer-reviewed research reports that investigated the in vivo use of vaccines for the prevention of disease caused by EHV-1 in domesticated horses. Main outcomes of interest included pyrexia, abortion, neurologic disease, viremia, and n...
Impact of Chlorogenic Acid on Peripheral Blood Mononuclear Cell Proliferation, Oxidative Stress, and Inflammatory Responses in Racehorses during Exercise.
Antioxidants (Basel, Switzerland)    October 28, 2023   Volume 12, Issue 11 1924 doi: 10.3390/antiox12111924
Dąbrowska I, Grzędzicka J, Niedzielska A, Witkowska-Piłaszewicz O.Green coffee extract is currently of great interest to researchers due to its high concentration of chlorogenic acid (CGA) and its potential health benefits. CGA constitutes 6 to 10% of the dry weight of the extract and, due to its anti-inflammatory properties, is a promising natural supplement and agent with therapeutic applications. The purpose of our study was to discover the effects of CGA on peripheral blood mononuclear cell proliferation, and the production of pro- and anti-inflammatory cytokines as well as reactive oxidative species (ROS) in horses during exercise. According to the find...
Strains of Anaplasma phagocytophilum from horses in Ohio are related to isolates from humans in the northeastern USA.
Microbiology spectrum    October 26, 2023   Volume 11, Issue 6 e0263223 doi: 10.1128/spectrum.02632-23
Chien RC, Mingqun L, Yan Q, Randolph N, Huang W, Wellman M, Toribio R, Rikihisa Y.The tick-borne obligatory intracellular bacterium Anaplasma phagocytophilum infects humans as well as domesticated and wild animals, causing a febrile disease collectively called granulocytic anaplasmosis. The epidemiology and the host species specificity and zoonotic potential of A. phagocytophilum strains remain unclear. In this study, ankA (encoding ankyrin A) and p44 gene sequences of A. phagocytophilum were determined in clinical specimens from horses in Ohio and compared with those found in A. phagocytophilum strains from various hosts and geographic regions. With increasing numbers of s...
Leptospirosis in horses: Sentinels for a neglected zoonosis? A systematic review.
Veterinary world    October 14, 2023   Volume 16, Issue 10 2110-2119 doi: 10.14202/vetworld.2023.2110-2119
Díaz EA, Arroyo G, Sáenz C, Mena L, Barragán V.Leptospirosis is considered a neglected tropical zoonosis in low-income countries due to surveillance system limitations and non-specificity of symptoms. Humans become infected through direct contact with carrier animals or indirectly through Leptospira-contaminated environments. Conventionally, equines have been considered an uncommon source of leptospirosis, but recent publications in Latin America suggest that their role in the maintenance and dispersion of the bacteria could be more relevant than expected, as horses are susceptible to a wide variety of zoonotic Leptospira spp. from domesti...
Efficacy of the oral supplement, Equine Omega Complete, for the prevention of gastric ulcers and alpha-tocopherol supplementation in horses.
Journal of veterinary internal medicine    September 29, 2023   Volume 37, Issue 6 2529-2534 doi: 10.1111/jvim.16877
Williams Louie E, Nieto J, Wensley F, Morgan JM, Finno CJ, Berryhill EH.Omega-3 fatty acid and alpha-tocopherol supplementation reduces gastric ulcer formation in humans and rodents; however, efficacy of prevention in horses is unknown. Equine Omega Complete (EOC) is an oral supplement containing omega-3 fatty acids and alpha-tocopherol. Objective: Determine if EOC supplementation prevents gastric ulcers and increases serum alpha-tocopherol concentrations in healthy horses. Methods: Nine thoroughbred geldings; 5-13 years old. Methods: Prospective randomized block design, repeated in crossover model. Horses were administered EOC, omeprazole, or water PO for 28 ...
Positron emission tomography assessment of metacarpal/metatarsal condylar fractures post surgical repair: Prospective study in 14 racehorses.
Veterinary surgery : VS    September 21, 2023   Volume 53, Issue 1 131-142 doi: 10.1111/vsu.14031
Bergstrom TC, Spriet M, O'Brion J, Carpenter R.To assess 18F-sodium fluoride (18F-NaF) positron emission tomography (PET) findings associated with metacarpal/metatarsal condylar fractures at the time of fracture repair and through healing. Methods: Prospective descriptive study. Methods: Fourteen Thoroughbred racehorses. Methods: 18F-NaF PET was performed within 4 days of surgical metacarpal/metatarsal condylar fracture repair, on both the injured and contralateral limb. Follow-up PET scans were offered at 3- and 5-months post fracture repair. Areas of abnormal uptake were assessed using a previously validated grading system. Results: Ei...
Helminth infection in horses – a cross-sectional study from stables in Lower Silesia (Poland).
Polish journal of veterinary sciences    September 20, 2023   Volume 26, Issue 3 401-407 doi: 10.24425/pjvs.2023.145046
Hildebrand W, Zielińska P, Hildebrand J, Zaleśny G.Parasitosis in horses may be uncontrolled and expose breeders and owners to serious financial losses or, possibly, to the loss of animals. Therefore, the prevention and monitoring of the development of parasitic diseases should play an important role in the breeding process. The aim of this study was to confirm the influence of factors such as age, breed, herd size, deworming program, and type of anthelmintics, on the prevalence and intensity of parasites (helminths) in domestic horses in Lower Silesia. The study was carried out between August and November of 2020. The samples of horse feces w...
MicroRNAs in equine Endometritis: A review of pathophysiology and molecular insights for diagnostic and therapeutic strategies.
International immunopharmacology    September 17, 2023   Volume 124, Issue Pt B 110949 doi: 10.1016/j.intimp.2023.110949
Asif S, Umar T, Umar Z, Jamil H, Feng H, Zhang P, Umer S.Endometritis plays an important role in mare infertility. Certain infectious agents interfere with the innate immune system of endometrium, causing a systemic inflammatory response that lasts for a long time and circulates via the blood or cellular degeneration, leading to endometritis due to bacterial endotoxins. Different small, non-coding RNA molecules are involved in many biological functions. For instance, microRNAs (miRNAs) are involved in the post-transcriptional regulation of gene expression. These miRNAs are important regulators of gene expression, primarily via inhibiting transcripti...
An Investigation of the Suitability of Viscosity Detection in Estimating IgG Content in Mare Colostrum.
Journal of equine veterinary science    September 16, 2023   Volume 131 104926 doi: 10.1016/j.jevs.2023.104926
Schneider F, Sievert M, Buettner K, Wehrend A.An adequate supply of colostrum is important for the prevention of hypogammaglobulinaemia in foals. In addition to the quantity of colostrum consumed and the time of consumption, the quality of the colostrum, the immunoglobulin (Ig) G concentration, is crucial. The aim of this study was to determine whether the viscosity of equine colostrum was a suitable estimate of IgG concentration. IgG content of colostrum was measured by ELISA and viscosity directly measured with a cone plate viscometer and indirectly assessed with a funnel. Analysis of 56 colostrum samples obtained from 40 mares at diffe...
Longitudinal humoral immune response and maternal immunity in horses after a single live-attenuated vaccination against African horse sickness during the disease outbreak in Thailand.
Veterinary world    August 19, 2023   Volume 16, Issue 8 1690-1694 doi: 10.14202/vetworld.2023.1690-1694
Kunanusont N, Taesuji M, Kulthonggate U, Rattanamas K, Mamom T, Thongsri K, Phannithi T, Ruenphet S.African horse sickness (AHS) has become a newly emerging disease after an outbreak in northeastern Thailand in March 2020. Mass vaccination in horses with live-attenuated AHS virus (AHSV) vaccine is essential for AHS control and prevention. This study aimed to monitor the longitudinal humoral immune response before and after a single vaccination using a live-attenuated vaccine against AHS in stallions, mares, and pregnant mares, including maternal immunity in foals born from pregnant mares during the outbreak in Thailand. Unassigned: A total of 13 stallions and 23 non-pregnant and 21 pregnant ...
Bacterial Periodontitis in Horses: An Epidemiological Study in Southern Italy.
Animals : an open access journal from MDPI    May 30, 2023   Volume 13, Issue 11 1814 doi: 10.3390/ani13111814
Occhiogrosso L, Capozza P, Buonavoglia A, Decaro N, Trotta A, Marin C, Corrente M.Equine periodontal disease (EPD) is a painful oral inflammatory syndrome characterized by multifactorial pathogenesis. Although it is well known that bacterial proliferation and consequent gingivitis are caused by the decomposition process of food residues, in hypsodont species, the pathogenetic role and the different bacterial species involved in the progression of EPD must be fully clarified. This study aimed to investigate the association of bacteria, including the complex red bacteria (RCB), with EPD, and to evaluate possible EPD risk factors. Bacterial species, including , , (belonging t...
Use of human behaviour change models to investigate horse owner intention to adopt emergency colic recommendations.
Equine veterinary journal    May 25, 2023   doi: 10.1111/evj.13955
Lightfoot KL, Frost E, Burford JH, England GCW, Freeman SL.Behavioural models are widely used within human medicine to understand beliefs and intention associated with major health interventions. Objective: To investigate horse-owner beliefs and practices associated with emergency colic planning. Methods: Cross-sectional study. Methods: An online survey incorporating the Trans-Theoretical Model of behaviour change and the Theory of Planned Behaviour was developed to assess owner intention to adopt three areas of emergency colic planning: (1) prevention/recognition, (2) involvement of others and (3) personal preparation. Participants were recruited usi...
Human Injuries Associated with the Transport of Horses by Road.
Animals : an open access journal from MDPI    May 10, 2023   Volume 13, Issue 10 1594 doi: 10.3390/ani13101594
Riley CB, Padalino B, Rogers CW, Thompson KR.There is an increased understanding of shared human-animal risk in terms of "one welfare", whereby when animals are at risk, so are people, so preventing injury to one species may also prevent injury to the other. Because transport-related injuries to horses are common, the authors considered this paradigm to study road equine transport-related injuries to humans in New Zealand. The aim was to determine their frequency and associated factors by distributing a survey to horse industry participants through industry organisations asking about their horse activities, road transport experiences, an...
Extracellular vesicles in the treatment and prevention of osteoarthritis: can horses help us translate this therapy to humans?
Extracellular vesicles and circulating nucleic acids    April 17, 2023   Volume 4, Issue 2 151-169 doi: 10.20517/evcna.2023.11
O'Brien TJ, Hollinshead F, Goodrich LR.Osteoarthritis (OA) is a common joint disease affecting humans and horses, resulting in significant morbidity, financial expense, and loss of athletic use. While the pathogenesis is incompletely understood, inflammation is considered crucial in the development and progression of the disease. Mesenchymal stromal cells (MSCs) have received increasing scientific attention for their anti-inflammatory, immunomodulatory, and pro-regenerative effects. However, there are concerns about their ability to become a commercially available therapeutic. Extracellular vesicles (EVs) are now recognized to play...
Horseback Riding-Related Injuries in Portugal and Prevention Strategies.
Journal of sport rehabilitation    January 23, 2023   Volume 32, Issue 4 409-414 doi: 10.1123/jsr.2022-0101
Pinto LV, Gouveia FC, Ramalho JF, Silva SR, Silva JR.Horse riding (HR) has gain popularity in Portugal, thereby increasing the number of related injuries. This study identifies frequently occurring injuries in Portuguese riders, the conditions under which they occur, and preventive measures. Methods: A retrospective cohort study. Methods: We included 216 Portuguese riders practicing HR at the time of the study with ≥1 year of experience. Data were obtained from a questionnaire that characterized first and second rider injuries; we opted for a systematic method to assess the riders' injuries, in a temporal order. Questions regarding demographi...
Preventative Care: Managing the Geriatric Horse with Integrative Therapies.
The Veterinary clinics of North America. Equine practice    October 13, 2022   Volume 38, Issue 3 475-483 doi: 10.1016/j.cveq.2022.06.005
Boldt E.Horses 15 years of age and older now account for a significant portion of the equine population. Integrative therapies can provide important diagnostic and treatment tools for managing and maintaining the health of geriatric horses. Aged horses are often afflicted with chronic disease processes that are difficult to effectively manage with conventional medicinal approaches, such as laminitis and osteoarthritis. Diagnostic and therapeutic approaches using integrative therapies, such as acupuncture and spinal manipulation, are presented in this article for managing aged horses with metabolic dis...
Gut Fungal Microbiome Responses to Natural Cryptosporidium Infection in Horses.
Frontiers in microbiology    July 6, 2022   Volume 13 877280 doi: 10.3389/fmicb.2022.877280
Wang Y, Li X, Chen X, Kulyar MF, Duan K, Li H, Bhutta ZA, Wu Y, Li K.It is critical to characterize changes in the structure and composition of the host fungal community in natural infection, because it gives the possible overview of gut microbiome in host homeostasis and disease progression. A total of 168 rectal fecal samples were collected and examined using nPCR. The positive samples were double-checked using 18S rDNA high-throughput sequencing. After confirmation, ITS high-throughput sequencing was utilized to investigate the fungal community's response to natural infection. Results showed that a total of three positive samples (1.79%) were identified wi...
Efficacy of Lidocaine Topical Solution in Reducing Discomfort Reaction of Horses to Intramuscular Vaccination.
Animals : an open access journal from MDPI    June 28, 2022   Volume 12, Issue 13 1659 doi: 10.3390/ani12131659
Torcivia C, McDonnell S.Vaccinations via intramuscular injection are a key component of preventative health care in horses. Development of problematic behavioral aversion to injections is quite common. Our clinical impression has been that topical anesthetic applied to injection sites can reduce the behavioral reaction; however, this has not been critically tested. To blindly evaluate efficacy, either 5% or 10% topical lidocaine solution or 0% control was applied to injection sites for 78 ponies two minutes before intramuscular vaccination. Mean reaction scores on a scale of 0-3 were 0.84 (se 0.18) for 5% lidocaine s...
1 2 3 6