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Endoscopic surgery in the treatment of contaminated and infected synovial cavities.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 613-619 doi: 10.2746/042516403775467225
Wright IM, Smith MR, Humphrey DJ, Eaton-Evans TC, Hillyer MH.Contamination and infection of synovial cavities are a common occurrence in clinical practice and, if inadequately treated, may have career or life threatening consequences for affected horses. Objective: The objectives in treating contamination and infection of joints, tendon sheaths and bursae are most effectively met by endoscopic surgery. Methods: Over a 6 year period, cases of synovial contamination and infection admitted to a referral clinic were evaluated and treated endoscopically. The horses received local and systemic antimicrobial drugs with minimal nonsteroidal anti-inflammatory me...
Ovarian function and morphology in the mare after multiple follicular punctures.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 575-579 doi: 10.2746/042516403775467243
Bøgh IB, Brink P, Jensen HE, Lehn-Jensen H, Greve T.In the mare, ultrasound-guided transvaginal oocyte recovery and transfer might offer a way to circumvent the demanding procedures of in vitro embryo production. Before clinical application, the possible consequences for subsequent fertility have to be considered. Objective: To examine ovarian function and morphology in mares after repeated follicular punctures. Methods: A total of 14-26 follicular puncture sessions were conducted on each of 4 Norwegian pony mares over a period of 8 years. The ovaries of these mares were recovered by bilateral ovariectomy or at post mortem and subjected to macr...
Large-volume injection gas chromatography-mass spectrometry for automated broad-spectrum drug screening in horse urine.
Journal of analytical toxicology    October 1, 2003   Volume 27, Issue 6 325-331 doi: 10.1093/jat/27.6.325
Stanley SD, McKemie D, Skinner W.A rapid, sensitive, and rugged method for detecting drugs and drug metabolites in extracts of horse urine is described. The use of large-volume injection (LVI) gas chromatography-mass spectrometry (GC-MS) for analysis of horse urine extracts allowed automation of the derivatization procedure and reduction of the sample volume from 5 mL to 1 mL of urine. An autosampler and temperature-programmable inlet were used to automatically dissolve the sample extract and form trimethylsilyl derivatives of over 200 analytes. The suitability of this procedure for routine GC-MS detection of approximately 80...
An evaluation of diagnostic data in comparison to the results of liver biopsies in mature horses.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 554-559 doi: 10.2746/042516403775467216
Durham AE, Smith KC, Newton JR.The diagnostic value of several investigative procedures commonly used during the evaluation of suspected equine hepatopathy cases has not been specifically quantified in previous studies. Objective: No noninvasive procedures would clearly discriminate between horses with and without significant liver disease. Methods: Histopathology of biopsy samples was used as the 'gold standard' technique for definitive diagnosis of the presence or absence of significant liver disease. Clinical, ultrasonographic and clinicopathological data obtained during the investigation of 82 suspected cases of hepatop...
Male, female and management risk factors for non-return to service in Dutch mares.
Preventive veterinary medicine    October 1, 2003   Volume 61, Issue 1 17-26 doi: 10.1016/s0167-5877(03)00128-4
van Buiten A, Westers P, Colenbrander B.The "effect" of stallion, mare and management-related factors on the odds of pregnancy per cycle in the horse were identified and quantified from the breeding records of Dutch Warmblood (n=4491), Friesian (n=1467) and Shetland-pony mares (n=3267) mated either naturally or by artificial insemination to one of the 88 stallions between 1992 and 1996. A mare was considered to be pregnant when she did not return to oestrous within 28 days of the last insemination. For Dutch Warmblood horses, the percentage of mares that did not return for service within 28 days (NR28) varied between studfarms and r...
Liver disease: contributions to diagnostic and prognostic aids.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 522-523 doi: 10.2746/042516403775467289
Byars TD.No abstract available
Comparison of the caudal lung borders determined by percussion and ultrasonography in horses with recurrent airway obstruction.
Acta veterinaria Hungarica    October 1, 2003   Volume 51, Issue 3 249-258 doi: 10.1556/AVet.51.2003.3.1
Bakos Z, Vörös K, Kellokoski H, Reiczigel J.The aim of the study was to evaluate the diagnostic value of thoracic percussion and ultrasonography with the help of distance measurements and statistical methods in the determination of the caudal lung border in horses with recurrent airway obstruction (RAO). Examinations were performed on 11 healthy, warm-blooded horses of different breeds, age and grade of disease. First, the caudal lung border was determined by the traditional indirect percussion method in the 10th, 12th, 14th and 16th intercostal spaces at the end of inspiration and expiration on both sides of the thorax. To apply standa...
Characterisation of movement pattern and velocities of stallion spermatozoa depending on donor, season and cryopreservation.
Acta veterinaria Hungarica    October 1, 2003   Volume 51, Issue 3 395-408 doi: 10.1556/AVet.51.2003.3.13
Warnke C, Tuchscherer A, Alm H, Kanitz W, Blottner S, Torner H.The aim of the study was to compare different types of movement pattern and velocities of stallion spermatozoa depending on cryopreservation during breeding and non-breeding season. Ejaculates were collected from four stallions during May (n = 24) and December (n = 24). Parameters of sperm movement were evaluated by computer-aided sperm analysis (CASA) system, and included percentages of motile spermatozoa, different patterns of motility, the velocity, linearity (LIN), amplitude of lateral head displacement (ALH) and beat-cross frequency (BCF). In winter the average percentages of motility wer...
Small-world topology of UK racing: the potential for rapid spread of infectious agents.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 586-589 doi: 10.2746/042516403775467298
Christley RM, French NP.The topology of the network of contacts between individuals has important effects on infectious disease dynamics within a population. Here we examine for the first time a network of contacts between training yards that occurred through racing. Objective: To explore the topology of this network and to consider the effects of the network on the potential for disease transmission. Methods: Race data from one week was analysed. Contacts were defined as occurring between trainers that raced horses in the same race and hence one trainer could contact another trainer several times. A connection was s...
A preliminary evaluation of the use of equine neutrophil elastase 2A concentration in synovial fluid as a marker for joint inflammation in horses.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 623-626 doi: 10.2746/042516403775467306
Dagleish MP, Wakeman KD, McDiarmid AM.No abstract available
Ovarian granulosa cell tumours adherent to other abdominal organs; surgical removal from 2 warmblood mares.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 627-632 doi: 10.2746/042516403775467261
Rambags BP, Stout TA, Rijkenhuizen AB.No abstract available
It’s all in the mix: infection transmission in populations.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 526-528 doi: 10.2746/042516403775467315
Wood JL, Newton JR, Daly J, Park AW, Mumford JA.No abstract available
Retrospective analysis of historical, clinical, ultrasonographic, serum biochemical and haematological data in prognostic evaluation of equine liver disease.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 542-547 doi: 10.2746/042516403775467324
Durham AE, Newton JR, Smith KC, Hillyer MH, Hillyer LL, Smith MR, Marr CM.Results of noninvasive tests of liver disease do not always correlate with the degree of hepatic disease nor outcome of the case. Objective: To investigate the prognostic value of data collected using noninvasive tests during the investigation of cases of suspected liver disease in mature horses. Objective: Much of the data gathered during the investigation of suspected hepatopathy cases offers little prognostic guidance and interpretation of such data can be misleading. Methods: The results from a range of common and noninvasive diagnostic techniques applied in 116 mature horses with suspecte...
West Nile virus infection of Thoroughbred horses in South Africa (2000-2001).
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 601-605 doi: 10.2746/042516403775467180
Guthrie AJ, Howell PG, Gardner IA, Swanepoel RE, Nurton JP, Harper CK, Pardini A, Groenewald D, Visage CW, Hedges JF, Balasuriya UB, Cornel AJ....West Nile virus (WNV) infection is endemic in southern Africa. With the recent emergence of WNV infection of horses in Europe and the USA the present study was performed to estimate the risk of seroconversion to WNV in a cohort of 488 young Thoroughbred (TB) horses. Objective: To estimate the risk of seroconversion to WNV among a cohort of South African TB yearlings sold at the 2001 National Yearling Sales (NYS) and to determine whether the risk varied geographically. Two horses were also infected with a recent South African isolate of WNV to evaluate its virulence in horses. Methods: Serum sa...
Inclined running increases pulmonary haemorrhage in the Thoroughbred horse.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 581-585 doi: 10.2746/042516403775467199
Kindig CA, Ramsel C, McDonough P, Poole DC, Erickson HH.Capillary stress failure-induced (exercise-induced) pulmonary haemorrhage (EIPH) during intense running in horses is thought to involve both intravascular (i.e. mean pulmonary arterial pressure [Ppa] > 100 mmHg) and extravascular (e.g. negative inspiratory pressure swings) mechanisms. Objective: That inclined running would reduce breathing frequency (coupled to stride frequency) and increase tidal volume thus increasing lung volume changes and intrapleural pressure swings resulting in more pronounced EIPH. Methods: Six Thoroughbred horses were run to volitional fatigue (incremental step tes...
Lateral transmission of equine arteritis virus among Lipizzaner stallions in South Africa.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 596-600 doi: 10.2746/042516403775467162
Guthrie AJ, Howell PG, Hedges JF, Bosman AM, Balasuriya UB, McCollum WH, Timoney PJ, MacLachlan NJ.A serological study conducted in 1995 revealed that 7 stallions at the Lipizzaner Centre, Gauteng, South Africa, were seropositive for antibody to equine arteritis virus (EAV). A Lipizzaner stallion imported into South Africa from Yugoslavia in 1981 had previously (1988) been confirmed to be an EAV carrier. Despite being placed under life-long breeding quarantine, EAV had been transmitted between stallions at the Lipizzaner Centre. Objective: To investigate the phylogenetic relationships between the strain of EAV shed in the semen of the original carrier stallion and strains recovered from the...
Development and application of a scoring system for prognostic evaluation of equine liver biopsies.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 534-540 doi: 10.2746/042516403775467171
Durham AE, Smitht KC, Newton JR, Hillyer MH, Hillyer LL, Smith MR, Marr CM.The study was designed to investigate the prognostic value of liver biopsy during investigation of cases of suspected liver disease in mature horses. Objective: That liver biopsy is the most prognostically useful technique in common usage in the investigation of suspected liver disease. Methods: This study examined the prognostic value of liver biopsy during the investigation of suspected liver disease in 73 mature horses. Histopathological variables comprising fibrosis, irreversible cytopathology, inflammatory infiltration, haemosiderin accumulation and biliary hyperplasia were found to be si...
Ventriculocordectomy reduces respiratory noise in horses with laryngeal hemiplegia.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 570-574 doi: 10.2746/042516403775467135
Brown JA, Derksen FJ, Stick JA, Hartmann WM, Robinson NE.Show and performance horse with laryngeal hemiplegia (LH) often present for excessive respiratory noise rather than significant exercise intolerance. Therefore, the goal of surgery in these horses is to reduce respiratory noise but there are no quantitative studies evaluating the effect of any upper-airway surgery in LH-affected horses. Objective: To determine whether bilateral ventriculocordectomy (VC) reduces respiratory noise in exercising horses with laryngeal hemiplegia. Methods: Six Standardbred horses with normal upper airways were used in this study. Respiratory sounds and inspiratory ...
Equine hepatic disease: the effect of patient- and case-specific variables on risk and prognosis.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 549-552 doi: 10.2746/042516403775467207
Smith MR, Stevens KB, Durham AE, Marr CM.Liver disease is fairly common in horses and, although previous literature suggests that fatality rates are high, impressions gained from current clinical practice suggest that this is no longer the case. Objective: A case-control study was undertaken in 2 hospitals to investigate whether age, gender or breed type predisposed horses to developing hepatic disease, with the additional aim of determining whether these factors and disease category had any effect on outcome. Methods: Eighty-eight cases were identified by review of computerised archives at 2 hospitals. Three cases admitted immediate...
Effect of lateral heel wedges on sagittal and transverse plane kinematics of trotting Shetland ponies and the influence of feeding and training regimes.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 606-612 doi: 10.2746/042516403775467252
Back W, Remmen JL, Knaap J, de Koning JJ.Lateral heel wedges are used to treat horses and ponies with patella fixation or bone spavin. However, these therapies are purely empirically based and lack scientific evidence. Objective: Lateral heel wedges would change joint motion in the sagittal, but mainly in the transversal planes, in healthy horses. This effect would be increased by restricted feeding and decreased by extra training. Methods: A group of 24 Shetland ponies age 3 years was used, as foals had been assigned to restricted and ad libitum (ad lib) feeding, and low and high level training groups of 6 animals each. An experienc...
Differences in polymorphonucleocyte function and local inflammatory response between horses and ponies.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 561-569 doi: 10.2746/042516403775467234
Wilmink JM, Veenman JN, van den Boom R, Rutten VP, Niewold TA, Broekhuisen-Davies JM, Lees R, Armstrong S, van Weeren PR, Barneveld A.Wound healing proceeds faster in ponies than in horses and complications during healing, such as wound infection, occur less frequently in ponies. Earlier studies suggested that this difference might be related to differences in the initial post traumatic inflammatory response. Objective: That polymorphonuclear leucocyte (PMN) function and profiles of humoral factors in local inflammatory processes are different in horses and ponies. Methods: PMNs were isolated from venous blood of horses and ponies. Chemotaxis and reactive oxygen species (ROS) production was determined. Tissue cages were impl...
Antimicrobial resistance: the microbe’s struggle for survival.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 530-531 doi: 10.2746/042516403775467144
Wise R.No abstract available
Severe hypertriglyceridaemia in clinically ill horses: diagnosis, treatment and outcome.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 590-595 doi: 10.2746/042516403775467270
Dunkel B, McKenzie HC.Sporadic measurement of serum triglycerides in depressed and inappetant clinically ill horses revealed severe hypertriglyceridaemia without visible evidence of lipaemia on several occasions, leading to the inclusion of serum triglyceride concentrations in the routine serum biochemistry evaluation of our hospital. Since then, more cases have been identified and treated for hypertriglyceridaemia, raising questions about the prevalence, predisposing factors and significance of these findings. Objective: 1) Severe hypertriglyceridaemia without visible opacity of the serum occurs more commonly in c...
Ophthalmic lesions in 83 geriatric horses and ponies.
The Veterinary record    October 1, 2003   Volume 153, Issue 11 319-322 doi: 10.1136/vr.153.11.319
Chandler KJ, Billson FM, Mellor DJ.Ophthalmic lesions were detected in 67 of 83 horses and ponies aged 15 years or more. Degeneration of the vitreous, followed by senile retinopathy, were the most common lesions and both of them became more common with advancing age, although few of the owners reported disturbances of vision in their animals.
Different CREM-isoform gene expression between equine and human normal and impaired spermatogenesis.
Theriogenology    September 27, 2003   Volume 60, Issue 7 1357-1369 doi: 10.1016/s0093-691x(03)00142-0
Blöcher S, Behr R, Weinbauer GF, Bergmann M, Steger K.Histone-to-protamine exchange causes chromatin condensation ceasing gene expression in elongating spermatids. Gene expression of protamines is regulated by the transcription factor cAMP-responsive element modulator (CREM). Altered CREM expression results in male infertility, as shown by CREM-knock-out mice being sterile due to round spermatid maturation arrest and patients exhibiting round spermatid maturation arrest revealing a lack or substantial reduction of both CREM-mRNA and CREM-protein. Similar defects in histone-to-protamine exchange have been suggested in infertile stallions exhibitin...
Serum beta-carotene and alpha-tocopherol in horses fed beta-carotene via grass-meal or a synthetic beadlet preparation with and without added dietary fat.
Journal of animal physiology and animal nutrition    September 27, 2003   Volume 87, Issue 3-4 174-180 doi: 10.1046/j.1439-0396.2003.00430.x
Kienzle E, Kaden C, Hoppe PP, Opitz B.The serum response of beta-carotene as an indicator of bioavailability was compared after feeding beta-carotene (0.8 mg/kg body weight) either from grass meal or a synthetic beadlet preparation (Lucarotin). Both were each given without or with added dietary vegetable fat (2-2.5% vs. 6.6% fat in dry matter) in a Latin square design with four horses. The nutritionally complete diet was supplemented with alpha-tocopherol (4 mg/kg body weight). Each treatment period (4 weeks, two serum samples) was followed by a washout period of 4 weeks with low intakes of beta-carotene (traces) and alpha-tocophe...
Studies on feed digestibilities in captive Asian elephants (Elephas maximus).
Journal of animal physiology and animal nutrition    September 27, 2003   Volume 87, Issue 3-4 160-173 doi: 10.1046/j.1439-0396.2003.00429.x
Clauss M, Loehlein W, Kienzle E, Wiesner H.In order to test the suitability of the horse as a nutritional model for elephants, digestibility studies were performed with six captive Asian elephants on six different dietary regimes, using the double marker method with acid detergent lignin as an internal and chromium oxide as an external digestibility marker. Elephants resembled horses in the way dietary supplements and dietary crude fibre content influenced digestibility, in calcium absorption parameters and in faecal volatile fatty acid composition. However, the absolute digestibility coefficients achieved for all nutrients are distinc...
Effects of oat processing on the glycaemic and insulin responses in horses.
Journal of animal physiology and animal nutrition    September 27, 2003   Volume 87, Issue 3-4 96-104 doi: 10.1046/j.1439-0396.2003.00420.x
Vervuert I, Coenen M, Bothe C.This study was conducted to evaluate the effects of different oat processing techniques on the plasma glucose and insulin response in horses. In a cross-over design, six horses (ages 4-15 years, mean body weight+/-SD: 450+/-37 kg) were fed in random order: untreated oats, finely ground, steam-flaked and popped oats. The total oat intake varied between 1.05-1.5 kg/day, and the amount of diet was adjusted to a starch content of 630 g starch per day and horse (1.2-1.5 g starch/kg BW/day). During the stabilization period of 10 days, horses additionally received 6 kg grass hay. Following this adapt...
Reactive oxygen species promote tyrosine phosphorylation and capacitation in equine spermatozoa.
Theriogenology    September 27, 2003   Volume 60, Issue 7 1239-1247 doi: 10.1016/s0093-691x(03)00144-4
Baumber J, Sabeur K, Vo A, Ball BA.The objective of this study was to examine the influence of reactive oxygen species (ROS) on equine sperm capacitation. Motile equine spermatozoa were separated on a discontinuous Percoll gradient, resuspended at 10 x 10(6)ml in Tyrode's medium supplemented with BSA (0.5%) and polyvinyl alcohol (0.5%) and incubated at 39 degrees C for 2h with or without the xanthine (X; 0.1mM)-xanthine oxidase (XO; 0.01 U/ml) system or NADPH (0.25 mM). The importance of hydrogen peroxide or superoxide for capacitation was determined by the addition of catalase (CAT; 150 U/ml) or superoxide dismutase (SOD; 150 ...
The course of some bone remodelling plasma metabolites in healthy horses and in horses offered a calcium-deficient diet.
Journal of animal physiology and animal nutrition    September 27, 2003   Volume 87, Issue 3-4 149-159 doi: 10.1046/j.1439-0396.2003.00428.x
de Behr V, Daron D, Gabriel A, Remy B, Dufrasne I, Serteyn D, Istasse L.An inquiry was carried out to assess the concentrations of plasma metabolites related to bone remodelling in 21 saddle horses of Warmblood breed aged 4-26 years, five draught horses of Ardennes breed aged 4-10 years, and 10 Ardennes foals aged 9-11 months. They were fed according to normal feeding practice in Belgium. The changes in some bone remodelling plasma metabolite concentrations were studied when an unbalanced diet was offered and later corrected for four Warmblood horses. Bone formation was evaluated by bone alkaline phosphatase (BALP), total alkaline phosphatase (TALP) and osteocalci...