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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Development of a prognostic scoring system for systemic inflammatory response syndrome in donkeys.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70202
Barnabé MA, Bamford NJ, Elliott J, Chang YM, Rickards K, Menzies-Gow NJ.Systemic inflammatory response syndrome (SIRS) is associated with increased mortality in horses with gastrointestinal (GI) disease. However, there are no data relating to naturally occurring SIRS in donkeys. Objective: To determine SIRS frequency in donkeys with GI disease. To develop a donkey-specific prognostic SIRS score. Methods: Retrospective case series. Methods: Clinical records from donkeys presenting with GI disease in two independent cohorts (development cohort: n = 400, UK; validation cohort: n = 36, Australia) were reviewed. Age, sex, heart rate, respiratory rate, rectal te...
Renal Perfusion in Healthy Horses: A Feasibility Study With Contrast-Enhanced Ultrasound. This study assessed the feasibility of contrast-enhanced ultrasound (CEUS) for evaluating renal perfusion in horses and compared perfusion parameters between age groups. In a prospective study, eight healthy horses were divided into young (3-5 years, n = 4) and old (16-17 years, n = 4) groups. All animals underwent B-mode, Doppler ultrasonography, and CEUS of the right kidney after an intravenous bolus of SonoVue (0.02 mL/kg). Qualitative analysis assessed contrast kinetics, whereas quantitative parameters (peak intensity, time to peak [TP], area under the curve, and wash-out time) were o...
Laser neoureterocystostomy to treat ectopic ureters.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70201
Smith C, Parente EJ.Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity. Identification of a minimally invasive, effective technique would significantly improve prognosis. Objective: To describe the procedure and outcomes of cystoscopic guided laser neoureterocystostomy in three fillies. Methods: Case series. Methods: Retrospective review of three cases treated wi...
Cheek tooth extraction in geriatric versus non-geriatric horses.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70199
Mair E, Nekouei O, Trummer-Schug P, Haralambus R, Biermann NM.Age-related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population. Objective: To describe clinical features, treatments, complication rates and short-term outcomes of horses undergoing oral cheek tooth extraction and treatment of odontogenic sinusitis, and to compare findings between geriatric and non-geriatric horses. Methods: Retrospective analysis of clinical...
Embryo developmental kinetics and vitrification in relation to pregnancy outcome, foaling percentage and foal sex.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70197
Peere S, Dewulf M, Van den Branden E, Papas M, Broothaers K, De Coster T, Briote I, Hedia M, Angel-Velez D, Hoogewijs M, Govaere J, Smits K.While fast in vitro embryo development has been associated with improved outcomes, the relationships of slow in vitro embryo development and vitrified versus fresh in vitro produced (IVP) embryo transfer to foaling percentage and foal sex are less explored. Objective: To determine the relationships of (1) day of blastocyst formation (D7-11 after intracytoplasmic sperm injection (ICSI)) and (2) vitrification and warming method (one- and three-step) versus fresh transfer with pregnancy, early pregnancy loss (EPL), foaling percentage and foal sex. Methods: Retrospective clinical study. Methods: B...
Roux-en-Y gastrojejunostomy and jejunojejunostomy for pyloric obstruction bypass in a horse and a foal.
Equine veterinary journal    May 31, 2026   doi: 10.1002/evj.70203
Gandini M, Bolz N, Czech C, Hartman M, Giusto G.Gastric outflow obstruction in horses is a rare but challenging condition, often resulting from either congenital anomalies or acquired lesions such as chronic ulceration or pyloric polyps. Conventional surgical bypass procedures, including gastrojejunostomy (GJ) or gastroduodenostomy and less commonly duodenojejunostomy, can restore patency but may lead to postoperative complications. Objective: To describe the presentation, surgical management, and postoperative outcome of two horses-an adult and a foal treated with Roux-en-Y gastrojejunostomy combined with a side-to-side jejunojejunostomy (...
Prevalence of cardiac arrhythmias in poorly performing horses.
Open veterinary journal    May 31, 2026   Volume 16, Issue 5 2961-2969 doi: 10.5455/OVJ.2026.v16.i5.39
Aliraqi OM, Albadrani BA.Electrocardiogram abnormalities are common in racehorses and can affect performance. Unassigned: This study aimed to analyze the results of electrocardiographic problems and measure the frequencies of various cardiac arrhythmias. Unassigned: This cross-sectional study was conducted between September 2023 and August 2024. Standard electrocardiographic recordings were obtained from all horses, and cardiac troponin levels were measured. Out of the 114 poorly performing adult horses, 10 cases without arrhythmia were considered the control group. Seventy-four horses (64.9%) had at least one type of...
Pathology of sudden death in racehorses: a review. Uzal FA, Asin J, Diab S, Henderson E, Engiles JB, Kennedy L, Schild C.Sudden death (SD) is the second most important syndrome associated with death in racehorses. The cause of SD in a large number of horses remains undetermined, and, in many of these cases, causes are not found by gross or microscopic postmortem examinations. Among the known causes of SD are traumatic injuries, including fractures of skull, neck, and pelvis; intoxications (e.g., anticoagulant rodenticides); and others. For many cases of SD in which no significant lesions are found, heart failure, probably associated with arrhythmias, is suspected. Precise phenotypic characterization of SD in hor...
Evaluation of two point-of-care molecular diagnostic platforms for rapid detection of equine Hendra virus.
Veterinary and animal science    May 30, 2026   Volume 33 100713 doi: 10.1016/j.vas.2026.100713
Hulse L, Izzard L, Nagendrakumar SB, Colling A, Underwood D, Driver L, Williams DT, Ahern B.Hendra virus (HeV) is a lethal zoonotic pathogen endemic to eastern Australia, posing significant risks to equine and human health. Rapid field detection of HeV enables timely intervention and outbreak management. This study evaluated candidate point-of-care (POC) molecular diagnostic platforms for HeV detection in equine samples: including a loop-mediated isothermal amplification (DARQ RT-LAMP) assay and real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR). Comparative analytical evaluation demonstrated that RT-qPCR exhibited superior analytical sensitivity relativ...
Estimating the economic value of working donkeys in Ethiopia.
Preventive veterinary medicine    May 30, 2026   Volume 254 106926 doi: 10.1016/j.prevetmed.2026.106926
Asteraye GB, Jobling R, Jemberu WT, Pinchbeck G, Knight-Jones TJD, Chaters GL, Rushton J.There is limited empirical evidence on the quantitative economic contribution of donkeys to livelihoods, leading to their undervaluation and exclusion from policy. Here an enterprise budget analysis is embedded within a stochastic dynamic population model for three production systems in Ethiopia to evaluate system inputs, outputs and the economic contribution of donkeys. The model was parameterised using data from household surveys, focus group discussions and key informant interviews, supplemented by literature. The economic value of donkeys' (unpaid) homestead and agricultural services was e...
Management of Equine Post-Extraction Cheek Tooth Alveoli: Application of Alveolar Plugs.
Animals : an open access journal from MDPI    May 30, 2026   Volume 16, Issue 11 1678 doi: 10.3390/ani16111678
Śmich J, Górski K, Maśko M, Borowska M, Turek B, Domino M.Preservation of dentition remains the primary goal of equine dentistry; however, cheek tooth extraction is required in cases of severe dental pathology. Following tooth extraction, management of the post-extraction alveolus remains a significant clinical challenge due to its large size and susceptibility to contamination with feed material and bacteria. To mitigate these risks, alveolar plugs are commonly used to protect the alveolus, stabilize the blood clot, and support granulation tissue formation. This review summarizes the current case reports and research articles regarding the use of al...
Horse species symposium: Current and future outlook on equine industry, research trends, and opportunities: How to promote a sustainable field into the future.
Journal of animal science    May 29, 2026   Volume 104 skag137 doi: 10.1093/jas/skag137
Cerqueira de Melo Vasco AC, Brooks S, White-Springer SH, Hammer CJ, Bruemmer JE, Yoho T, Jacobs R.The equine industry represents a complex and evolving sector with substantial economic, social, and scientific significance, yet it faces growing challenges related to funding constraints, societal expectations for animal welfare, regulatory pressures, and rapid scientific and technological change. This article synthesizes perspectives presented at the 2025 Horse Species Symposium, held during the joint Annual Meeting of the American Society of Animal Science and Canadian Society of Animal Science, which convened experts from academia, government, and industry to evaluate the current state and...
Efficacy of 0.5% Tretinoin in the Treatment of Equine Aural Plaques.
Veterinary dermatology    May 29, 2026   doi: 10.1111/vde.70090
de Mattos FS, Conceição LG, Schuartz YGH, Silva VRM, Fidélis CF, Mansur FC, Teixeira CS, Sancler-Silva YFR, Oliveira-Filho JP, Borges AS....Equine aural plaques are a benign form of auricular papillomatosis caused by equine papillomavirus. Despite the efficacy of 5% imiquimod cream, a marked local reaction is frequently observed during therapy, often requiring sedation before application. Objective: The aim of this study was to evaluate the efficacy and potential adverse effects of 0.5% topical tretinoin in the treatment of equine aural plaques. We hypothesised that tretinoin would be effective, with fewer adverse effects compared to imiquimod. Methods: The study included 10 horses of both sexes, aged between 7 months and 15 y...
Association Between Vaquejada Practice and Biomarkers of Oxidative Stress, Inflammation, and Muscle Damage in Quarter Horses.
Veterinary sciences    May 29, 2026   Volume 13, Issue 6 531 doi: 10.3390/vetsci13060531
Nascimento RCMD, Guedes EAB, Silva RBD, Cerqueira ITI, Freire CCDS, Câmara DR, Moura FA, Escodro PB, Goulart MOF.Vaquejada (VQ) is a traditional Brazilian sport demanding high performance from Quarter Horse (QH) athletes. This study aimed to identify modifications in hematological, biochemical, inflammatory, and oxidative stress biomarkers associated with VQ training, comparing conditioned and non-conditioned horses. Blood samples were collected at rest from 70 healthy QH horses: 60 athletes (VQ-conditioned athlete group-AG) and 10 sedentary controls (breeding horses-CG). Using Linear Mixed Models alongside comprehensive hematological and biochemical analyses, the study found that AG horses exhibited an ...
Recent Advances in Natural Products for Colitis: Mechanisms and Translational Perspectives.
Veterinary sciences    May 29, 2026   Volume 13, Issue 6 532 doi: 10.3390/vetsci13060532
Jin F, Shi Y, Wang L, Kuang T, Ren K, Xu J, Zhang Y, Niu C, Cheng J, Pan S.Colitis is a chronic relapsing inflammatory disorder characterized by persistent mucosal inflammation, epithelial barrier disruption, oxidative stress, immune dysregulation, and gut microbiota imbalance. Although current therapies have improved disease management, their long-term use is still limited by incomplete response, relapse, adverse effects, and high cost. Natural products have attracted increasing attention as promising candidates for colitis intervention because of their structural diversity, broad bioactivity, and multitarget regulatory potential. In veterinary medicine, colitis and...
A Revised View on Equine Hypertriglyceridemia, Hyperlipidemia, and Hyperlipemia.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00022-2 doi: 10.1016/j.cveq.2026.04.007
Dunkel B.Hypertriglyceridemia, also known as hyperlipidemia or hyperlipemia, affects equids of all breeds and ages, mostly secondary to a negative energy balance triggered by a disease process. Increased triglyceride concentrations (TG) have been described in well-eating equids with endocrinopathies, atypical myopathy, severe liver disease, and after treatment with sodium-glucose transporter 2 inhibitors. The fact that equids can have substantially increased TG without showing clinical signs prompted reevaluation of the clinical effects of hypertriglyceridemia. As long as the consequences of high TG ar...
Prognosis of Equine Liver Diseases.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00027-1 doi: 10.1016/j.cveq.2026.04.012
Durham AE.Prognostic information in equine liver disease can be gleaned from historical, clinical, clinicopathological, ultrasonographic, and histopathological features. However, given the multiple causes and subtypes of liver disease affecting horses worldwide, prognostic data might not be suitable for universal application across all cases. Most evidence has been established for horses with chronic hepatopathies and extrapolation to acute cases should be avoided. In chronic liver disease the presence and severity of clinical signs and serum markers including total globulins, albumin, and bile acids ar...
Topical betulinic acid for treatment of equine melanoma and sarcoid.
Frontiers in veterinary science    May 28, 2026   Volume 13 1821503 doi: 10.3389/fvets.2026.1821503
Moreno C, Mudge M, Horne R, Yardley J.Betulinic acid, a natural pentacyclic triterpenoid, has demonstrated anti-inflammatory and anti-tumor properties in vitro, including activity against equine melanoma and sarcoid. However, there is limited in vivo evidence evaluating its clinical efficacy. The objective of this study was to assess the safety and efficacy of a compounded 1% betulinic acid cream for the treatment of equine cutaneous melanoma and sarcoid. Unassigned: This prospective, randomized, double-blinded, placebo-controlled clinical trial enrolled client-owned horses with melanoma or sarcoid tumors. Horses received either a...
Equine Liver Histopathology.
The Veterinary clinics of North America. Equine practice    May 28, 2026   Volume 42, Issue 2 249-266 doi: 10.1016/j.cveq.2026.04.003
Jager MC.This review summarizes best practices for equine liver biopsy, including when to perform a biopsy, techniques for sample collection and handling, and strategies to optimize diagnostic yield. It discusses the interpretive framework used by pathologists, common diagnostic challenges, and prognostic scoring systems. Limitations such as sampling error and variability among observers are considered alongside ancillary testing, immunohistochemistry, and in situ hybridization. Emphasis is placed on the importance of communication between clinicians and pathologists to maximize diagnostic and prognost...
Thoracic electrical impedance tomography using a two-plane electrode configuration in horses.
Equine veterinary journal    May 28, 2026   doi: 10.1002/evj.70188
Studer N, Byrne D, Raisis A, Adler A, Cheong J, Secombe C, Schramel JP, Mosing M.Traditional one-plane (oneP) electrical impedance tomography (EIT) electrode configurations limit evaluation to a convex lens-shaped lung slice, prone to overrepresentation of central areas. Two-plane (twoP) EIT is expected to refine this technique and result in more representative lung imaging. Objective: To compare ventilation distribution using single slice reconstructions, obtained with twoP or oneP. Methods: Computational modelling and in vivo exploratory randomised experimental trial. Methods: A finite element simulation model of oneP and twoP was calculated to estimate captured lung fie...
Miscellaneous Equine Liver Conditions.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00025-8 doi: 10.1016/j.cveq.2026.04.010
Taylor SD, Brooks SN.Miscellaneous equine liver conditions not covered in other chapters include chronic active hepatitis, Tyzzer's disease, seasonal idiopathic hepatitis, neoplasia, and idiopathic persistent hyperbilirubinemia. Chronic active hepatitis refers to inflammatory and fibrotic liver disease with an unknown cause. Treatment is aimed at reducing inflammation. Tyzzer's disease is caused by Clostridium piliforme infection and causes acute necrotizing hepatitis in foals. Successful treatment with antimicrobial therapy and supportive care is rare. Seasonal idiopathic hepatitis is a winter disease of Midweste...
Biliary Disorders in Horses.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00020-9 doi: 10.1016/j.cveq.2026.04.005
Peek SF, Sebastian K.This review will mainly focus on the presentation, diagnosis, and treatment of cholangiohepatitis in adult horses. The condition is often accompanied by some degree of intrahepatic and/or extrahepatic biliary obstruction with "sludgy" bile or actual choleliths. In horses, these calculi are typically composed of calcium bilirubinate, rather than cholesterol. There is a propensity for cholangiohepatitis to become a recurrent, chronic condition and patient management should reflect this. Although much rarer, foreign body obstruction, neoplasia and, in some parts of the world, liver flukes can als...
Derivatisation-free FIA-MS/MS assay for rapid simultaneous screening of atypical myopathy biomarkers and acylcarnitine profiles from dried blood spots.
Analytical and bioanalytical chemistry    May 27, 2026   doi: 10.1007/s00216-026-06566-3
Kadláčková M, Dobešová D, Ivanovová E, Masař R, Jahn P, Šamonilová E, Friedecký D, Brumarová R.Atypical myopathy (AM) is a frequently fatal, toxin-induced disease in horses, characterised by acute progression and mortality rates exceeding 70% within 72 h. The disease is caused by ingestion of seedlings or seeds of certain maple species that contain the toxins hypoglycin A (HGA) and methylenecyclopropylglycine (MCPrG). Early diagnosis depends on reliable detection of these compounds and their metabolites. However, most available LC-MS/MS assays are limited by derivatisation requirements and dependence on serum and urine matrices. Here, a rapid derivatisation-free flow injection analysis...
Effect of N-acetyl cysteine treatment on uterine cytokine and chemokine profiles in mares with persistent breeding-induced endometritis.
Journal of equine veterinary science    May 27, 2026   Volume 165 106033 doi: 10.1016/j.jevs.2026.106033
Khan FA, Caissie MD, Wagner B, Scholtz EL, Chenier TS.Persistent breeding-induced endometritis (PBIE) is a major cause of infertility in mares. Recent research has shown that PBIE-affected mares treated with intrauterine N-acetyl cysteine (NAC) 12 hours before breeding showed no improvement in clinical signs at 12- and 60-hours post-breeding. Objective: The present study was designed to examine the effects of NAC treatment on the uterine inflammatory cytokine and chemokine profiles in PBIE-affected mares. Methods: Using a randomized, blinded, cross-over design, mares susceptible to PBIE (n=9) were allocated to Control and Treatment cycles with at...
Anatomical distribution of meconium detected by focused abdominal ultrasound in hospitalized healthy and sick neonatal foals.
Journal of equine veterinary science    May 27, 2026   Volume 165 105945 doi: 10.1016/j.jevs.2026.105945
Maggi A, Ellero N, Busoni V, Imposimato I, Castagnetti C, Lanci A, Mariella J, Freccero F.Meconium impaction is a common cause of neonatal colic in foals, yet its ultrasonographic appearance and distribution remain poorly characterized. Objective: This study aimed to describe the frequency, distribution, and ultrasonographic appearance of meconium in hospitalized neonatal foals using a standardized focused ultrasound (FUS) abdominal protocol. Methods: The FUS protocol included 9 acoustic windows (3 left-sided, 3 ventral, 3 right-sided) and was performed once during hospitalization by a single operator using a curvilinear transducer. Results: Thirty-six foals (16 healthy and 20 sick...
Integrative and conjugative elements carrying high-level gentamicin resistance genes in Streptococcus dysgalactiae subsp. equisimilis from horses.
Microbial genomics    May 27, 2026   Volume 12, Issue 5 001722 doi: 10.1099/mgen.0.001722
Rochegüe T, Hughes S, Saras E, Gillet B, Drapeau A, Glaser P, Madec JY, Haenni M, Lupo A.In streptococci, the acquisition of high-level gentamicin resistance (HLGR) abolishes the synergy with beta-lactams, constituting a medical concern for humans and animals. This synergy between gentamicin and beta-lactams is useful to treat severe infections like endocarditis, among others. HLGR has been characterized mostly in roup B Streptococci mediated by the bi-functional gene (6)-(2).HLGR- subsp. () (=27) were isolated from the uterus of mares during a routine screening before fecundation. One HLGR- was isolated from a lymph node of a mare. The mares resided in six different studs locat...
Retained fetal membranes in light breed mares hospitalized for attended parturition.
Journal of equine veterinary science    May 27, 2026   Volume 165 105946 doi: 10.1016/j.jevs.2026.105946
Fischetti L, Perina F, Mariella J, Castagnetti C, Lanci A.Retention of fetal membranes (RFM) is well described in draft breeds, whereas data on light breed mares remains limited and inconsistent. Objective: This retrospective study aimed to describe the frequency, associated factors, treatments, and consequences of RFM in light breed mares hospitalized for attended parturition. Methods: Medical records of 321 light breed mares hospitalized for attended parturition at the Veterinary Teaching Hospital, University of Bologna, were retrospectively reviewed. Data collected included: breed, previous history of RFM, age, parity, assisted reproductive techni...
Evaluation of doppler indexes of the lateral palmar digital artery in lame sport horses.
Research in veterinary science    May 27, 2026   Volume 209 106276 doi: 10.1016/j.rvsc.2026.106276
de Chiara M, De Matteis A, Del Prete C, Costanza D, Montano C, Auletta L, Marinelli VG, Buono F, Pasolini MP.Although lateral palmar digital artery (LPDA) flow velocity does not differ between forelimbs, horses with lameness typically reduce loading of the affected limb during the weight-bearing phase. This study aimed to assess whether Pulsed-Wave (PW) Doppler indices of the (LPDA) blood flow differ between the two forelimbs in horses with unilateral forelimb lameness, and whether these differences correlate with lameness severity. Twenty-seven lame and 15 healthy horses were enrolled. All Doppler ultrasonographic examinations were performed by a single operator, blinded to both the presence or abse...
Outcomes and racing performance in thoroughbreds following a long-term injury sustained during a jump race in Great Britain.
The Veterinary record    May 26, 2026   doi: 10.1002/vetr.70807
McDonald S, Verheyen KLP, Chang YM, Allen SE.Limited literature is available about the career outcomes of horses sustaining a long-term injury (LTI) in a jump race. Methods: All Thoroughbreds that sustained an LTI, defined as any non-fatal musculoskeletal injury requiring a minimum 90-day break from racing, in a British jump race between May 2018 and April 2023 were followed up for at least 24 months and outcomes described. Pre-injury racing performance was compared between horses that did and did not return to racing, and post-injury racing performance was compared between horses that sustained tendon/ligament injuries and fractures. R...
Use of Intraperitoneal Lidocaine in Horses Undergoing Laparotomy for Colic.
Animals : an open access journal from MDPI    May 26, 2026   Volume 16, Issue 11 1616 doi: 10.3390/ani16111616
Giulivi F, Nannarone S.Perioperative lidocaine is widely used in horses with acute abdomen for its analgesic, prokinetic, anti-inflammatory, and anti-endotoxic effects, although evidence of its visceral analgesic efficacy remains inconclusive. Given the potential of alternative routes of administration for local anaesthetics, this prospective, randomised, unblinded clinical trial evaluated whether intraperitoneal (IP) lidocaine improves early postoperative recovery, including recovery from anaesthesia and the first 24 h after laparotomy for colic. A Multifactorial Numerical Rating Composite Pain Scale for equines wa...