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Topic:Equine Health
Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Morphological and Behavioural Predictors of Motor Laterality in Domestic Horses: A Cross-Sectional Field Study. Motor laterality in horses affects performance, training, and welfare. A simple morphological marker for laterality would help riders, trainers, and veterinarians identify likely locomotor asymmetries early. This study tested whether observable morphological and behavioural characteristics were associated with rider-perceived motor laterality in domestic horses, using a cross-sectional observational field study design conducted in the Blida and Algiers regions of Algeria. The study included 100 regularly ridden domestic horses. Mane orientation, facial whorl characteristics, standing curvature...
Ultrasonography of the spleen, kidneys and bladder in healthy Mangalarga Marchador horses across different life stages. This study is the first breed-specific ultrasonographic reference values for spleen, kidneys, and bladder in Mangalarga Marchador horses from different life stages. Objective: The aim of this study was to establish a normal reference range of measurements of the spleen, kidneys and bladder, as well as to describe the anatomy and sonographic characteristics of these organs in Mangalarga Marchador horses. Methods: Abdominal ultrasound examinations were performed in 88 Mangalarga Marchador horses of both sexes, aged 1, 7 and 15 days, monthly from their 1st to the 11th month of age ando n their 1s...
Forage chemical composition drives early metabolic shifts in ponies fed different haylages. Rapid changes between feeds can cause dysbiosis and colic in horses. The metabolic consequences of transitioning between haylages (HY) are currently unknown. Objective: To characterise urinary and faecal metabonomics in ponies transitioned between HY varying in botanical composition and physiological age and to evaluate the speed of metabolic adaptation. Methods: In vivo experiments repeated Latin Square. Methods: Eight Welsh Mountain ponies were fed four HY (R1, R2, M1, M2) across 4 × 15-day periods; a structured 3-day (Days 13-15) changeover was observed: old:new 70:30, 50:50and 30:70....
Cumulus cell DNA fragmentation as non-invasive biomarker of equine oocyte quality in in vitro embryo production. The efficiency of in vitro embryo production in animal species is constrained by the absence of practical, non-invasive biomarkers to assess oocyte quality. Cumulus cell DNA fragmentation index (CC-DFI) has been proposed as a biomarker in humans, but data in animals remain limited. Objective: This study investigated the association of CC-DFI with in vitro maturation (IVM) and intracytoplasmic sperm injection (ICSI) outcomes in horses, and its relationship with mare-related factors, autumnal transition period, cumulus cell viability, and cumulus expansion. Methods: Cumulus-oocyte complexes (COC...
Pass rates using the FEI noseband measurement device at British Dressage 2025 Championships. Appropriate fitting of equipment provides horse comfort and avoids compromising equine welfare. In May 2025, the Fédération Equestre Internationale (FEI) introduced an evidence-based measuring device that is passed beneath the noseband to ensure sufficient laxity. Objective: To study the use of the FEI noseband device during mandatory tack and equipment checks at British Dressage Championships. Methods: Observational. Methods: Noseband testing was observed for a total of 523 horses competing at the 2025 British Dressage National Championship, Middle Tour Championship and Area Festival Champi...
Cervical articular process joint versus ventral cervical stabilization in horses: A biomechanical study. To determine the biomechanical properties and modes of failure of a single level equine cervical spine immobilized with unilateral or bilateral articular process joint (APJ) stabilization, ventral cervical stabilization (VCS) and non-stabilized controls. Methods: Ex vivo experimental study. Methods: A total of 24 equine cadaver cervical spines. Methods: Cervical spinal units (C4-C5) were randomly assigned to four groups (n = 6/group): unilateral APJ stabilization, bilateral APJ stabilization, VCS using pedicle screws and rod constructs, or non-stabilized. Non-destructive testing assessed k...
Antimicrobial stewardship priorities and prescribing in Australian equine practice. Antimicrobial resistance is a global health crisis that needs to be addressed by all areas of human and animal health sectors to safeguard effective antibiotics into the future. Understanding current antimicrobial prescribing patterns and veterinary antimicrobial stewardship (AMS) priorities is crucial for effective stewardship program design and sustainable uptake. Objective: To identify focus areas for stewardship interventions, implementation, resource allocation, and future campaign targets for equine practice. Methods: Cross-sectional study of equine veterinarians in Australia. Methods: A...
Long-term dynamics of gastrointestinal parasite egg shedding in a semi-feral Misaki horse population in Japan. This study investigated long-term gastrointestinal parasite egg shedding in a semi-feral Misaki horse population using 3200 fecal samples collected from 158 individually identified horses during five fiscal years (FY2019-FY2023; April 2019-March 2024). Strongyle-type eggs were detected in 91.7% of samples (2935/3200), with a mean count of 1352 eggs per gram (EPG). Repeated-measures analyses showed marked variation associated with fiscal year, season, age, and management history. Strongyle-type EPG values were generally higher in spring and summer than in autumn and winter, with the month-level...
A novel water additive increases voluntary water intake in healthy horses. To determine whether healthy horses would increase their voluntary water intake (VWI) when offered a novel water additive (NWA) compared to plain water (TAP) and water flavored with sweet feed, referred to as sweet tea (ST). Unassigned: 12 clinically healthy horses, aged 2 to 5 years old, were enrolled in the experimental crossover design. Four horses were assigned to each group for each of the 3 study weeks. The order that the horses were allocated to study groups was randomly assigned. All horses had access to 2 buckets filled to 16 L, one containing plain water (untreated bucket) and one co...
Serum amyloid A alone or in combination with white blood cell count and fibrinogen is associated with inflammatory disease status in horses undergoing elective anesthesia. The objective of this study was to assess the clinical utility of common systemic inflammatory markers (WBC count [WBCC], plasma fibrinogen, and serum amyloid A [SAA]) for the detection of disease in patients undergoing general anesthesia. Unassigned: A retrospective review of 1,002 surgical case records (February 2021 to June 2023) was performed. Systemically stable equine patients undergoing elective orthopedic and soft tissue procedures and that had WBCC, fibrinogen, and SAA evaluated preoperatively were eligible for inclusion. Disease status (healthy vs disease) was recorded for each case ...
Comparative Susceptibility of Donkey and Horse Sperm to Liquid-Storage Temperature. Preservation protocols for donkey sperm are based on those developed for horses, despite potential interspecific differences in cooling tolerance. This study compared horse and donkey sperm during long-term storage at 5°C and 17°C. Ejaculates from four stallions and four jacks (n = 16) were centrifuged, resuspended in skimmed milk-based extender, and stored at both temperatures. Sperm motility, plasma and acrosome membrane integrity, and morphology were evaluated after 1, 2 and 7 days. Fresh semen parameters showed no interspecific differences (p > 0.05). At 5°C, donkey sperm show...
Impact of a Riding Event and Ambient Temperature on the Heart Rate of Gotlandsruss Ponies. Visitors to zoos present unpredictable visual and auditory stimulation for captive animals. Coupled with high ambient temperatures this might prove stressful for animals involved in human interactions. This study aims to determine if Gotlandsruss ponies are stressed by visitors during a childrens riding event at Slottsskogen, a zoo park, in Gothenburg, Sweden and whether ambient temperature also had an impact. Decibel level, temperature, and the ponies heart rate were monitored during the event. Each pony's maximum rate during exercise and resting heart rate were measured to compare with heart...
Low-Field Magnetic Resonance Imaging Features of Axial Proximal Sesamoid Osteomyelitis and Intersesamoidean Ligament Rupture in a Horse. A 7-year-old Warmblood mare used for show jumping was evaluated for progressive left hindlimb lameness of 5 weeks' duration, localized clinically to the metatarsophalangeal region. Radiography revealed ill-defined osteolysis of the axial apical regions of both proximal sesamoid bones (PSBs). Due to rapid clinical deterioration, low-field magnetic resonance imaging was performed and demonstrated aggressive axial osteomyelitis of both PSBs, partial rupture of the intersesamoidean ligament and proximal scutum with herniation of synovium of the plantar joint recess, and an occult penetrating tract...
Validation of a novel instrumented hoof boot with pressure sensors using force plate gait kinetics in horses at walk and trot. Force plates (FP) are considered the gold standard for quantitative equine gait evaluation but are limited to experimental use. An instrumented hoof boot (IHB) with pressure sensors and an inertial measurement unit would allow clinicians to objectively assess kinetic parameters and gait symmetry. Objective: To validate the IHB by comparing kinetic parameters with obtained FP data. Methods: In vivo experiments. Methods: Twenty-seven horses were measured with IHBs on FPs at walk and trot. Mean value kinetic parameters recorded were: (1) peak vertical force (PVF) [N/kg]/peak vertical pressure (PV...
A single-cell RNA-seq dataset characterizing cellular diversity in healthy equine skin. The skin serves as the primary barrier tissue in horses and is frequently affected by immune-mediated dermatological conditions, most notably insect bite hypersensitivity (IBH). Yet, the cellular composition and transcriptional landscape of normal equine skin have never been characterized at single-cell resolution. Here, we present a single-cell RNA sequencing dataset of healthy equine skin comprising 85,574 high-quality transcriptomes from two horses, with one skin biopsy collected from each horse, divided into two portions for independent processing via manual or automated tissue dissociatio...
Nasopharyngeal and laryngopharyngeal collapse: intra- and interrater agreement supports novel endoscopic scoring classifications in horses. The contribution of reduced airway patency from heightened inspiratory pressure or active muscular contraction to the pathophysiology of pharyngeal collapse is unknown. Existing classifications refer to the entire pharyngeal region; however, anatomical differences are evident between rostral and caudal collapse. Novel classifications and grading systems are proposed to differentiate 2 pathologies: nasopharyngeal collapse (NPC; collapse of ≥ 1 pharyngeal wall rostral to the tip of the epiglottis; grades 0 through 4), and laryngopharyngeal collapse (LPC; collapse of ≥ 1 pharyngeal wall cauda...
Ursodeoxycholic Acid Oral Pharmacokinetics and Plasma Bile Acid Profile Changes in a Population of Healthy Neonatal Foals. Ursodeoxycholic acid (UDCA) is a secondary bile acid used in humans for the treatment of some cholestatic diseases. Interest in its potential use in equine patients with liver conditions has increased. Pharmacokinetic parameters in adult horses have recently been reported; however, they are not available for foals. The objective of this study was to characterize the pharmacokinetics of UDCA following a single oral dose of 15 mg/kg in six healthy neonatal foals and evaluate associated changes in bile acids (BA) profile. UDCA concentrations were measured using liquid chromatography-tandem mass...
Cooperative Care in Zoo, Livestock, and Companion Animals and Positive Reinforcement in Horses: A Scoping Literature Review. Cooperative care, training an animal to voluntarily participate in care procedures using positive reinforcement, may improve welfare and lower stress in horses. This scoping literature review synthesizes two bodies of research to analyze existing scientific evidence on cooperative care and explore its potential application for horses. Two literature searches were conducted in ScienceDirect, CABI Digital Library, PubMed, and Google Scholar using predefined search terms and eligibility criteria. Publications were reviewed against two sets of inclusion and exclusion criteria. A total of 1,518 rec...
Characterisation of microbial metabolite profiles across the gastrointestinal tract of horses fed on pasture, hay or oat-supplemented rations. Dietary composition substantially influences the intensity and site of microbial metabolite production in the gastrointestinal tract. These metabolites have numerous beneficial effects on equine health, but may also be involved in the development of gastrointestinal disorders. It remains unclear whether different feeding strategies, including starch supplementation, can alter microbial metabolite profiles along the gastrointestinal tract. This study aimed to compare the metabolite profiles of the microbial communities in the gastrointestinal tract of horses fed on pasture 24 h/day (PST; n =â...
Thymidine kinase 1 activity in serum and body cavity fluids of horses with lymphoma. The accuracy of serum thymidine kinase 1 (TK1S) as a biomarker of lymphoma in horses is variable. The value of measurement in body cavity fluid (TK1F) has not been established. Objective: (1) TK1F and TK1S will be higher in horses with lymphoma compared to diseased controls (DCs); (2) TK1F will be higher than TK1S; and (3) there will be a strong correlation between both measurements. Methods: Twenty animals in the lymphoma and 31 animals with nonneoplastic, gastrointestinal/respiratory disorders in DC group. Methods: This was a cross-sectional study using prospectively collected data and sampl...
Prior-informed population pharmacokinetic-pharmacodynamic modeling of dexamethasone in horses. Dexamethasone (DEX) is widely used in equine practice with diverse studies having characterized its pharmacokinetics (PK) and pharmacodynamics (PD) including our published comprehensive meta-analysis. Individual DEX concentrations in plasma and urine and serum cortisol from five studies (n = 32 horses) were analyzed using a minimal physiologically-based PK (mPBPK) model and a circadian baseline-indirect response PD model. The previous meta-analysis provided complex structural models to assess sources of variability across an array of studies involving intravenous (IV), intramuscular (IM) a...
The Impact of Track Incline on Musculoskeletal Injuries in Thoroughbred Racehorses in Training: A Retrospective Cohort Study of Fractures on Flat and Uphill Woodchip Surfaces. While race-day musculoskeletal injuries are well-documented, a considerable gap exists regarding fractures sustained during training, where Thoroughbred racehorses accumulate the majority of their high-speed exercise. In Japan, compliant woodchip tracks are frequently used, and uphill track geometries are a foundational element of conditioning. Objective: To quantify and describe the incidence and anatomical distribution of fractures occurring during training on flat versus uphill woodchip tracks over a 15-year period (2008-2022). Methods: A retrospective cohort study was conducted using centr...
Weigh tape more accurately estimates equine body weight than morphometric formula: a controlled technical assessment. Accurate body weight (BW) estimation in horses is essential for clinical and nutritional management; however, calibrated scales are often unavailable under field conditions. Objective: To compare the longitudinal accuracy and consistency of a commercial weigh tape and the Carroll and Huntington morphometric formula against calibrated digital scale measurements in adult horses. Methods: In a prospective longitudinal experimental study, six clinically healthy adult crossbred horses (mean real body weight [Rbw] 355.5 ± 21.2 kg) were monitored weekly for 63 days under controlled management condit...
Inflammatory phenotype and response to intradermal skin testing are not predictive of equine asthma diagnosis. The role of inflammation, allergy, and air quality in the pathogenesis of equine asthma has not yet been fully elucidated. Objective: To evaluate serum inflammatory cytokines, intradermal skin testing (IDT), and air quality in asthmatic horses. It was hypothesized that there would be an association between environmental allergies and poor air quality with asthma. Methods: 52 client-owned horses with clinical signs consistent with asthma were enrolled in this cross-sectional study. Horses were diagnosed with asthma based on the results of bronchoalveolar fluid (BALF) cytology. Blood samples wer...
Race-related fatalities in U.S. jump racing, 2023-2025: incidence and documentation across public reporting sources. Fatality reporting in National Steeplechase Association (NSA)-sanctioned U.S. jump racing is distributed across several public sources, and no single source consistently links the race incident with the final clinical outcome. Objective: To identify and verify race-related fatalities associated with NSA-sanctioned jump-racing starts, compare documentation across public sources, and estimate minimum confirmed fatality incidence. Methods: The study population included official starters in completed NSA-sanctioned hurdle/fence and timber races during 2023-2025. Potential fatalities reported by Ho...
Phenotypic associations between young horse assessments and orthopaedic diagnoses in insured Swedish Warmblood horses. Lameness is the most common health problem in riding horses, and insurance data have previously been used to investigate the prevalence of orthopaedic diagnoses in Swedish Warmblood (SWB) horses. Young horse performance testing is an important part of the SWB breeding programme and contributes data to the genetic evaluation. Assessed traits from these tests have been shown to be useful indicator traits of performance in show jumping and dressage, but their associations with orthopaedic health have not previously been investigated. Objective: To study the associations between assessed traits fr...
Retrospective investigation of equine parvovirus-hepatitis in Italy. Equine parvovirus-hepatitis (EqPV-H) has recently been identified as the etiological agent of Theiler's disease, a major cause of acute hepatitis and liver failure in horses. While iatrogenic transmission of EqPV-H is well-documented, the natural horizontal transmission of the virus remains poorly understood. This study provides the first comprehensive epidemiological investigation and molecular characterization of EqPV-H in equine populations across Italy. A total of 1320 archival serum samples from northern and southern Italy were screened for the presence of EqPV-H DNA by qPCR. The overall ...
Comparison of blind end closure techniques in equine ileum. To determine the difference in bursting pressure (BP), bursting wall tension (BWT), and closure speed between commonly utilized methods of ileal stump closure. Methods: Randomized experimental study. Methods: A total of 71 ileal segments from 18 healthy horses. Methods: Ileum was collected postmortem from 18 horses and divided into four segments. One end of each segment was closed using one of three techniques: Parker-Kerr (PK), gastrointestinal staples (ST), or gastrointestinal staples with a Lembert staple oversew (SO). Closure time was recorded. Control (C) segments were not altered. Segmen...
Distal limb wraps produce gait- and material-dependent post-exercise changes in stride timing and limb kinematics in horses. Distal limb wraps are widely used during equine exercise, but their effects on post-exercise kinematics and movement symmetry remain poorly defined. Objective: To determine whether elastic and fleece distal limb wraps alter temporal stride variables, distal limb kinematics, and axial movement symmetry after standardised round-pen exercise. Methods: Six adult horses completed a prospective crossover study with three conditions: no wraps, elastic wraps, and fleece wraps. Wraps were applied bilaterally to all distal limbs at an initial pressure of 20 mmHg. After 20 minutes of free round-pen exerc...
Serum osteocalcin is associated with scintigraphic abnormalities in lame and clinically sound racehorses. Musculoskeletal injury is a major welfare and economic challenge in racehorses, with stress-related bone injury contributing to training interruption and catastrophic failure. Advanced imaging modalities can detect early skeletal pathology but remain limited in routine screening environments. Circulating biomarkers of bone turnover may provide complementary indicators of skeletal remodelling but require validation against objective imaging findings. Objective: Evaluate whether osteocalcin (OC) and C-terminal telopeptide of type I collagen (CTX), or the CTX/OC ratio, are associated with scintig...
